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The role of dermoscopy and digital dermoscopy follow-up in the clinical diagnosis of melanoma: clinical and dermoscopic features of 99 consecutive primary melanomas.

Salerni G, Terán T, Alonso C, Fernández-Bussy R - Dermatol Pract Concept (2014)

Bottom Line: A total of 99 MMs were diagnosed in 89 patients (55% male) with a mean age of 50.8 (18-93) years.On clinical examination, 74.2 % of MMC met the 4 ABCD criteria, while only 30.7 % of MMRC and 8.3 % of MMDFU.Mean Breslow thickness was significantly lower in the MMDFU group (0.52 mm) than in the MMRC and MMDFU groups (0.77 and 1.43 mm respectively).

View Article: PubMed Central - PubMed

Affiliation: Hospital Provincial del Centenario de Rosario, Argentina, & Faculty of Medicine, Universidad Nacional de Rosario, Argentina ; Diagnóstico Médico Oroño, Rosario, Argentina.

ABSTRACT

Background: Early recognition is the most important intervention to improve melanoma prognosis.

Objective: To report the value of dermoscopy and digital dermoscopy in the clinical diagnosis of malignant melanoma (MM).

Methods: Retrospective analysis of 99 consecutive primary MMs diagnosed between 2010 and 2013. The MMs were divided into 3 groups: 1) the MM was the reason for consultation (MMC), 2) the MM was detected during routine control of nevi (MMRC), and 3) the MM was detected due to changes observed during digital dermoscopy follow-up (MMDFU). Clinical, dermoscopic and histologic features were assessed.

Results: A total of 99 MMs were diagnosed in 89 patients (55% male) with a mean age of 50.8 (18-93) years. Of all the MMs, 35 were the reason for patient consultation (MMC), 52 were detected during routine control of nevi (MMRC) and 12 were diagnosed due to changes observed with digital dermoscopy (MMDFU). On clinical examination, 74.2 % of MMC met the 4 ABCD criteria, while only 30.7 % of MMRC and 8.3 % of MMDFU. Most MMC were correctly classified as malignant according to dermoscopy, but 44.2% of MMRC and only 16.7% of MMDFU. 22.9% of MMC, 50% of MMRC and 58.3% of MMDFU were in situ. Mean Breslow thickness was significantly lower in the MMDFU group (0.52 mm) than in the MMRC and MMDFU groups (0.77 and 1.43 mm respectively).

Conclusions: The use of dermoscopy and digital dermoscopy allows the detection of MMs in early stages, even in the absence of specific criteria for malignancy.

No MeSH data available.


Related in: MedlinePlus

Dermoscopic images. MMC (A-D): (A) superficial extensive melanoma, Breslow 2.5 mm, Clark IV; (B) superficial extensive melanoma, Breslow 0.49 mm, Clark III; (C) superficial extensive melanoma, Breslow 1.7 mm, Clark IV; (D) Nodular melanoma, Breslow 3.7 mm, Clark V. MMRC (E-H): (E) superficial extensive melanoma, Breslow 0.75 mm, Clark III; (F) superficial extensive melanoma, Breslow 0.35 mm, Clark II; (G) In situ melanoma; (H) superficial extensive melanoma, Breslow 0.7 mm, Clark III. MMDFU (I-L): (I) in situ melanoma; (J) in situ melanoma; (K) superficial extensive melanoma, Breslow 0.7 mm, Clark III; (L) superficial extensive melanoma, Breslow 0.6 mm, Clark III. (Copyright: ©2014 Salerni et al.)
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f2-dp0404a07: Dermoscopic images. MMC (A-D): (A) superficial extensive melanoma, Breslow 2.5 mm, Clark IV; (B) superficial extensive melanoma, Breslow 0.49 mm, Clark III; (C) superficial extensive melanoma, Breslow 1.7 mm, Clark IV; (D) Nodular melanoma, Breslow 3.7 mm, Clark V. MMRC (E-H): (E) superficial extensive melanoma, Breslow 0.75 mm, Clark III; (F) superficial extensive melanoma, Breslow 0.35 mm, Clark II; (G) In situ melanoma; (H) superficial extensive melanoma, Breslow 0.7 mm, Clark III. MMDFU (I-L): (I) in situ melanoma; (J) in situ melanoma; (K) superficial extensive melanoma, Breslow 0.7 mm, Clark III; (L) superficial extensive melanoma, Breslow 0.6 mm, Clark III. (Copyright: ©2014 Salerni et al.)

Mentions: Most of MMC (N=25, 71.4%) displayed multicomponent pattern according to pattern analysis, followed by reticular pattern in 7 (15%), 2 lesions had starburst pattern and 1 unspecific pattern. In the MMRC group, more than half had reticular pattern (n=28), while only 19 (36.5%) display multicomponent pattern. In this group, globular and unspecific pattern where seen in 2 and 3 cases respectively. Among the melanomas detected due to changes during digital follow-up (MMDFU), almost 60% (n=7) had reticular pattern and 25% (n=3) multicomponent pattern, 16.6% (n=2) showed globular pattern (Figure 2).


The role of dermoscopy and digital dermoscopy follow-up in the clinical diagnosis of melanoma: clinical and dermoscopic features of 99 consecutive primary melanomas.

Salerni G, Terán T, Alonso C, Fernández-Bussy R - Dermatol Pract Concept (2014)

Dermoscopic images. MMC (A-D): (A) superficial extensive melanoma, Breslow 2.5 mm, Clark IV; (B) superficial extensive melanoma, Breslow 0.49 mm, Clark III; (C) superficial extensive melanoma, Breslow 1.7 mm, Clark IV; (D) Nodular melanoma, Breslow 3.7 mm, Clark V. MMRC (E-H): (E) superficial extensive melanoma, Breslow 0.75 mm, Clark III; (F) superficial extensive melanoma, Breslow 0.35 mm, Clark II; (G) In situ melanoma; (H) superficial extensive melanoma, Breslow 0.7 mm, Clark III. MMDFU (I-L): (I) in situ melanoma; (J) in situ melanoma; (K) superficial extensive melanoma, Breslow 0.7 mm, Clark III; (L) superficial extensive melanoma, Breslow 0.6 mm, Clark III. (Copyright: ©2014 Salerni et al.)
© Copyright Policy
Related In: Results  -  Collection

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f2-dp0404a07: Dermoscopic images. MMC (A-D): (A) superficial extensive melanoma, Breslow 2.5 mm, Clark IV; (B) superficial extensive melanoma, Breslow 0.49 mm, Clark III; (C) superficial extensive melanoma, Breslow 1.7 mm, Clark IV; (D) Nodular melanoma, Breslow 3.7 mm, Clark V. MMRC (E-H): (E) superficial extensive melanoma, Breslow 0.75 mm, Clark III; (F) superficial extensive melanoma, Breslow 0.35 mm, Clark II; (G) In situ melanoma; (H) superficial extensive melanoma, Breslow 0.7 mm, Clark III. MMDFU (I-L): (I) in situ melanoma; (J) in situ melanoma; (K) superficial extensive melanoma, Breslow 0.7 mm, Clark III; (L) superficial extensive melanoma, Breslow 0.6 mm, Clark III. (Copyright: ©2014 Salerni et al.)
Mentions: Most of MMC (N=25, 71.4%) displayed multicomponent pattern according to pattern analysis, followed by reticular pattern in 7 (15%), 2 lesions had starburst pattern and 1 unspecific pattern. In the MMRC group, more than half had reticular pattern (n=28), while only 19 (36.5%) display multicomponent pattern. In this group, globular and unspecific pattern where seen in 2 and 3 cases respectively. Among the melanomas detected due to changes during digital follow-up (MMDFU), almost 60% (n=7) had reticular pattern and 25% (n=3) multicomponent pattern, 16.6% (n=2) showed globular pattern (Figure 2).

Bottom Line: A total of 99 MMs were diagnosed in 89 patients (55% male) with a mean age of 50.8 (18-93) years.On clinical examination, 74.2 % of MMC met the 4 ABCD criteria, while only 30.7 % of MMRC and 8.3 % of MMDFU.Mean Breslow thickness was significantly lower in the MMDFU group (0.52 mm) than in the MMRC and MMDFU groups (0.77 and 1.43 mm respectively).

View Article: PubMed Central - PubMed

Affiliation: Hospital Provincial del Centenario de Rosario, Argentina, & Faculty of Medicine, Universidad Nacional de Rosario, Argentina ; Diagnóstico Médico Oroño, Rosario, Argentina.

ABSTRACT

Background: Early recognition is the most important intervention to improve melanoma prognosis.

Objective: To report the value of dermoscopy and digital dermoscopy in the clinical diagnosis of malignant melanoma (MM).

Methods: Retrospective analysis of 99 consecutive primary MMs diagnosed between 2010 and 2013. The MMs were divided into 3 groups: 1) the MM was the reason for consultation (MMC), 2) the MM was detected during routine control of nevi (MMRC), and 3) the MM was detected due to changes observed during digital dermoscopy follow-up (MMDFU). Clinical, dermoscopic and histologic features were assessed.

Results: A total of 99 MMs were diagnosed in 89 patients (55% male) with a mean age of 50.8 (18-93) years. Of all the MMs, 35 were the reason for patient consultation (MMC), 52 were detected during routine control of nevi (MMRC) and 12 were diagnosed due to changes observed with digital dermoscopy (MMDFU). On clinical examination, 74.2 % of MMC met the 4 ABCD criteria, while only 30.7 % of MMRC and 8.3 % of MMDFU. Most MMC were correctly classified as malignant according to dermoscopy, but 44.2% of MMRC and only 16.7% of MMDFU. 22.9% of MMC, 50% of MMRC and 58.3% of MMDFU were in situ. Mean Breslow thickness was significantly lower in the MMDFU group (0.52 mm) than in the MMRC and MMDFU groups (0.77 and 1.43 mm respectively).

Conclusions: The use of dermoscopy and digital dermoscopy allows the detection of MMs in early stages, even in the absence of specific criteria for malignancy.

No MeSH data available.


Related in: MedlinePlus