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Solitary myofibroma of the mandible in an adult with magnetic resonance imaging and positron emission tomography findings: a case report.

Tanaka Y, Yamada H, Saito T, Nakaoka K, Kumagai K, Fujihara H, Mishima K, Hamada Y - World J Surg Oncol (2014)

Bottom Line: The tumor was removed by marginal resection of the left mandible under general anesthesia.Histopathological findings revealed that the tumor stroma contained abundant thin-walled vessels.The postoperative course was uneventful, and we found no evidence of recurrence at the postoperative 34-month follow-up.

View Article: PubMed Central - HTML - PubMed

Affiliation: Department of Oral and Maxillofacial Surgery, Tsurumi University School of Dental Medicine, 2-1-3 Tsurumi, Tsurumi-ku, Yokohama, Japan. yamada-hi@tsurumi-u.ac.jp.

ABSTRACT
Myofibroma is a benign tumor composed of myoid spindle cells. The prevalence of myofibroma in the oral cavity is very low, with the mandible being the most common site. This report describes an adult case of myofibroma that arose on the mandible and includes magnetic resonance imaging (MRI) and positron emission tomography (PET) findings. On the MRI T1-weighted images, the tumor appeared with signal iso-intensity and was highly and heterogeneously enhanced with contrast material. On the T2-weighted images, it appeared with increased signal intensity. 18 F-fluorodeoxyglucose (FDG)-PET imaging showed abnormal strong accumulation of FDG in the left mandibular region. The tumor was removed by marginal resection of the left mandible under general anesthesia. Histopathological findings revealed that the tumor stroma contained abundant thin-walled vessels. The postoperative course was uneventful, and we found no evidence of recurrence at the postoperative 34-month follow-up.

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Preoperative MRI images. (A) T1-weighted axial image showing a mass of iso-intensity on the mandible (arrow). (B) Gadolinium-enhanced T1-weighted axial image showing a highly and heterogeneously enhanced mass (arrow). (C) T2-weighted axial image showing high signal intensity within the mass (arrow). (D) Short-tau inversion recovery images showing high signal intensity in the mass (arrow). MRI, magnetic resonance imaging.
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Figure 2: Preoperative MRI images. (A) T1-weighted axial image showing a mass of iso-intensity on the mandible (arrow). (B) Gadolinium-enhanced T1-weighted axial image showing a highly and heterogeneously enhanced mass (arrow). (C) T2-weighted axial image showing high signal intensity within the mass (arrow). (D) Short-tau inversion recovery images showing high signal intensity in the mass (arrow). MRI, magnetic resonance imaging.

Mentions: MRI examination was performed with a 1.5 Tesla system (Intera 1.5 T; Philips Healthcare, Eindhoven, The Netherlands). On the T1-weighted axial images, the mass appeared isointense and was highly and heterogeneously enhanced with gadolinium in the left mandibular region. On the T2-weighted axial images, it appeared with increased signal intensity. On short-tau inversion recovery coronal imaging, the mass also showed high signal intensity (Figure 2). The CT images (Brilliance CT 16; Philips Healthcare, Eindhoven, The Netherlands) showed no bony changes of the mandible (Figure 3). The PET study was performed with a dedicated PET scanner (ECAT ACCEL; Siemens Healthcare AG, Munich, Germany). Data were acquired after administration of 181.5 MBq 18 F-fluorodeoxyglucose (FDG), using the post-injection transmission acquisition method. The image showed abnormal strong accumulation of FDG in the left mandibular region with a maximum standard uptake value of 8.5. There were no abnormal accumulations of FDG in the cervical lymph nodes nor was there any uptake in the other organs (Figure 4A). The PET/CT fusion images showed that abnormal strong FDG accumulation corresponded to the mass on the left mandible (Figure 4B).


Solitary myofibroma of the mandible in an adult with magnetic resonance imaging and positron emission tomography findings: a case report.

Tanaka Y, Yamada H, Saito T, Nakaoka K, Kumagai K, Fujihara H, Mishima K, Hamada Y - World J Surg Oncol (2014)

Preoperative MRI images. (A) T1-weighted axial image showing a mass of iso-intensity on the mandible (arrow). (B) Gadolinium-enhanced T1-weighted axial image showing a highly and heterogeneously enhanced mass (arrow). (C) T2-weighted axial image showing high signal intensity within the mass (arrow). (D) Short-tau inversion recovery images showing high signal intensity in the mass (arrow). MRI, magnetic resonance imaging.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4230239&req=5

Figure 2: Preoperative MRI images. (A) T1-weighted axial image showing a mass of iso-intensity on the mandible (arrow). (B) Gadolinium-enhanced T1-weighted axial image showing a highly and heterogeneously enhanced mass (arrow). (C) T2-weighted axial image showing high signal intensity within the mass (arrow). (D) Short-tau inversion recovery images showing high signal intensity in the mass (arrow). MRI, magnetic resonance imaging.
Mentions: MRI examination was performed with a 1.5 Tesla system (Intera 1.5 T; Philips Healthcare, Eindhoven, The Netherlands). On the T1-weighted axial images, the mass appeared isointense and was highly and heterogeneously enhanced with gadolinium in the left mandibular region. On the T2-weighted axial images, it appeared with increased signal intensity. On short-tau inversion recovery coronal imaging, the mass also showed high signal intensity (Figure 2). The CT images (Brilliance CT 16; Philips Healthcare, Eindhoven, The Netherlands) showed no bony changes of the mandible (Figure 3). The PET study was performed with a dedicated PET scanner (ECAT ACCEL; Siemens Healthcare AG, Munich, Germany). Data were acquired after administration of 181.5 MBq 18 F-fluorodeoxyglucose (FDG), using the post-injection transmission acquisition method. The image showed abnormal strong accumulation of FDG in the left mandibular region with a maximum standard uptake value of 8.5. There were no abnormal accumulations of FDG in the cervical lymph nodes nor was there any uptake in the other organs (Figure 4A). The PET/CT fusion images showed that abnormal strong FDG accumulation corresponded to the mass on the left mandible (Figure 4B).

Bottom Line: The tumor was removed by marginal resection of the left mandible under general anesthesia.Histopathological findings revealed that the tumor stroma contained abundant thin-walled vessels.The postoperative course was uneventful, and we found no evidence of recurrence at the postoperative 34-month follow-up.

View Article: PubMed Central - HTML - PubMed

Affiliation: Department of Oral and Maxillofacial Surgery, Tsurumi University School of Dental Medicine, 2-1-3 Tsurumi, Tsurumi-ku, Yokohama, Japan. yamada-hi@tsurumi-u.ac.jp.

ABSTRACT
Myofibroma is a benign tumor composed of myoid spindle cells. The prevalence of myofibroma in the oral cavity is very low, with the mandible being the most common site. This report describes an adult case of myofibroma that arose on the mandible and includes magnetic resonance imaging (MRI) and positron emission tomography (PET) findings. On the MRI T1-weighted images, the tumor appeared with signal iso-intensity and was highly and heterogeneously enhanced with contrast material. On the T2-weighted images, it appeared with increased signal intensity. 18 F-fluorodeoxyglucose (FDG)-PET imaging showed abnormal strong accumulation of FDG in the left mandibular region. The tumor was removed by marginal resection of the left mandible under general anesthesia. Histopathological findings revealed that the tumor stroma contained abundant thin-walled vessels. The postoperative course was uneventful, and we found no evidence of recurrence at the postoperative 34-month follow-up.

Show MeSH
Related in: MedlinePlus