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Solitary myofibroma of the mandible in an adult with magnetic resonance imaging and positron emission tomography findings: a case report.

Tanaka Y, Yamada H, Saito T, Nakaoka K, Kumagai K, Fujihara H, Mishima K, Hamada Y - World J Surg Oncol (2014)

Bottom Line: The tumor was removed by marginal resection of the left mandible under general anesthesia.Histopathological findings revealed that the tumor stroma contained abundant thin-walled vessels.The postoperative course was uneventful, and we found no evidence of recurrence at the postoperative 34-month follow-up.

View Article: PubMed Central - HTML - PubMed

Affiliation: Department of Oral and Maxillofacial Surgery, Tsurumi University School of Dental Medicine, 2-1-3 Tsurumi, Tsurumi-ku, Yokohama, Japan. yamada-hi@tsurumi-u.ac.jp.

ABSTRACT
Myofibroma is a benign tumor composed of myoid spindle cells. The prevalence of myofibroma in the oral cavity is very low, with the mandible being the most common site. This report describes an adult case of myofibroma that arose on the mandible and includes magnetic resonance imaging (MRI) and positron emission tomography (PET) findings. On the MRI T1-weighted images, the tumor appeared with signal iso-intensity and was highly and heterogeneously enhanced with contrast material. On the T2-weighted images, it appeared with increased signal intensity. 18 F-fluorodeoxyglucose (FDG)-PET imaging showed abnormal strong accumulation of FDG in the left mandibular region. The tumor was removed by marginal resection of the left mandible under general anesthesia. Histopathological findings revealed that the tumor stroma contained abundant thin-walled vessels. The postoperative course was uneventful, and we found no evidence of recurrence at the postoperative 34-month follow-up.

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Photograph showing the mass on the mandible.
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Figure 1: Photograph showing the mass on the mandible.

Mentions: A 52-year-old woman was referred to the Department of Oral and Maxillofacial Surgery, Tsurumi University Dental Hospital (Yokohama, Japan) on 30 October 2010 for diagnosis and treatment of a mass on the left mandible. The patient had noticed the mass for 1 month. The mass grew rapidly from the extraction socket of the lower mandibular second molar. Past medical history revealed hypertension and hyperlipidemia, which were adequately controlled with medication. The patient’s family history was unremarkable. Physical examination revealed a rubbery sessile mass measuring 20 × 15 mm on the left mandible (Figure 1). The overlying oral mucosa looked absent. There was neither neuroparalysis nor cervical lymphadenopathy.


Solitary myofibroma of the mandible in an adult with magnetic resonance imaging and positron emission tomography findings: a case report.

Tanaka Y, Yamada H, Saito T, Nakaoka K, Kumagai K, Fujihara H, Mishima K, Hamada Y - World J Surg Oncol (2014)

Photograph showing the mass on the mandible.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4230239&req=5

Figure 1: Photograph showing the mass on the mandible.
Mentions: A 52-year-old woman was referred to the Department of Oral and Maxillofacial Surgery, Tsurumi University Dental Hospital (Yokohama, Japan) on 30 October 2010 for diagnosis and treatment of a mass on the left mandible. The patient had noticed the mass for 1 month. The mass grew rapidly from the extraction socket of the lower mandibular second molar. Past medical history revealed hypertension and hyperlipidemia, which were adequately controlled with medication. The patient’s family history was unremarkable. Physical examination revealed a rubbery sessile mass measuring 20 × 15 mm on the left mandible (Figure 1). The overlying oral mucosa looked absent. There was neither neuroparalysis nor cervical lymphadenopathy.

Bottom Line: The tumor was removed by marginal resection of the left mandible under general anesthesia.Histopathological findings revealed that the tumor stroma contained abundant thin-walled vessels.The postoperative course was uneventful, and we found no evidence of recurrence at the postoperative 34-month follow-up.

View Article: PubMed Central - HTML - PubMed

Affiliation: Department of Oral and Maxillofacial Surgery, Tsurumi University School of Dental Medicine, 2-1-3 Tsurumi, Tsurumi-ku, Yokohama, Japan. yamada-hi@tsurumi-u.ac.jp.

ABSTRACT
Myofibroma is a benign tumor composed of myoid spindle cells. The prevalence of myofibroma in the oral cavity is very low, with the mandible being the most common site. This report describes an adult case of myofibroma that arose on the mandible and includes magnetic resonance imaging (MRI) and positron emission tomography (PET) findings. On the MRI T1-weighted images, the tumor appeared with signal iso-intensity and was highly and heterogeneously enhanced with contrast material. On the T2-weighted images, it appeared with increased signal intensity. 18 F-fluorodeoxyglucose (FDG)-PET imaging showed abnormal strong accumulation of FDG in the left mandibular region. The tumor was removed by marginal resection of the left mandible under general anesthesia. Histopathological findings revealed that the tumor stroma contained abundant thin-walled vessels. The postoperative course was uneventful, and we found no evidence of recurrence at the postoperative 34-month follow-up.

Show MeSH
Related in: MedlinePlus