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An alternative to current therapies of functional dyspepsia: self-administrated transcutaneous electroacupuncture improves dyspeptic symptoms.

Ji T, Li X, Lin L, Jiang L, Wang M, Zhou X, Zhang R, Chen JDz - Evid Based Complement Alternat Med (2014)

Bottom Line: Physiological testing included gastric emptying and electrogastrography.It was found that (1) TEA but not sham-TEA significantly improved dyspeptic symptoms and 4 domains in quality of life; improvement was also noted in self-rated anxiety and depression scores; (2) gastric emptying was significantly and substantially increased with 2-week TEA but not sham-TEA; and (3) gastric accommodation was also improved with TEA but not sham-TEA, reflected as increased ingested nutrient volumes at the levels of satiety and maximum tolerance.These findings suggest a therapeutic potential of self-administrated TEA method for functional dyspepsia, possibly attributed to improvement in gastric motility.

View Article: PubMed Central - PubMed

Affiliation: Division of Gastroenterology, Department of Gastroenterology, First Affiliated Hospital, Nanjing Medical University, Nanjing 210029, China.

ABSTRACT
Functional dyspepsia is of high prevalence with little treatment options. The aim of this study was to develop a new treatment method using self-management transcutaneous electroacupuncture (TEA) for functional dyspepsia (FD). Twenty-eight patients with FD were enrolled and underwent a crossover clinical trial with 2-week TEA at ST36 and PC6 and 2-week sham-TEA at nonacupuncture sham-points. Questionnaires were used to assess symptoms of dyspepsia and quality of life. Physiological testing included gastric emptying and electrogastrography. It was found that (1) TEA but not sham-TEA significantly improved dyspeptic symptoms and 4 domains in quality of life; improvement was also noted in self-rated anxiety and depression scores; (2) gastric emptying was significantly and substantially increased with 2-week TEA but not sham-TEA; and (3) gastric accommodation was also improved with TEA but not sham-TEA, reflected as increased ingested nutrient volumes at the levels of satiety and maximum tolerance. These findings suggest a therapeutic potential of self-administrated TEA method for functional dyspepsia, possibly attributed to improvement in gastric motility.

No MeSH data available.


Related in: MedlinePlus

TEA accelerated gastric emptying in FD patients. ***P < 0.001, versus before TEA.
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fig6: TEA accelerated gastric emptying in FD patients. ***P < 0.001, versus before TEA.

Mentions: The difference between the treatment groups was statistically significant (P = 0.0017). The multiple comparison analysis revealed a significant increase after the TEA treatment in the rate of gastric emptying (44.3 ± 6.7% versus 75.7 ± 5.1%, P < 0.001) (Figure 6). However, such an increase was not noted with the sham-TEA treatment.


An alternative to current therapies of functional dyspepsia: self-administrated transcutaneous electroacupuncture improves dyspeptic symptoms.

Ji T, Li X, Lin L, Jiang L, Wang M, Zhou X, Zhang R, Chen JDz - Evid Based Complement Alternat Med (2014)

TEA accelerated gastric emptying in FD patients. ***P < 0.001, versus before TEA.
© Copyright Policy - open-access
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC4230003&req=5

fig6: TEA accelerated gastric emptying in FD patients. ***P < 0.001, versus before TEA.
Mentions: The difference between the treatment groups was statistically significant (P = 0.0017). The multiple comparison analysis revealed a significant increase after the TEA treatment in the rate of gastric emptying (44.3 ± 6.7% versus 75.7 ± 5.1%, P < 0.001) (Figure 6). However, such an increase was not noted with the sham-TEA treatment.

Bottom Line: Physiological testing included gastric emptying and electrogastrography.It was found that (1) TEA but not sham-TEA significantly improved dyspeptic symptoms and 4 domains in quality of life; improvement was also noted in self-rated anxiety and depression scores; (2) gastric emptying was significantly and substantially increased with 2-week TEA but not sham-TEA; and (3) gastric accommodation was also improved with TEA but not sham-TEA, reflected as increased ingested nutrient volumes at the levels of satiety and maximum tolerance.These findings suggest a therapeutic potential of self-administrated TEA method for functional dyspepsia, possibly attributed to improvement in gastric motility.

View Article: PubMed Central - PubMed

Affiliation: Division of Gastroenterology, Department of Gastroenterology, First Affiliated Hospital, Nanjing Medical University, Nanjing 210029, China.

ABSTRACT
Functional dyspepsia is of high prevalence with little treatment options. The aim of this study was to develop a new treatment method using self-management transcutaneous electroacupuncture (TEA) for functional dyspepsia (FD). Twenty-eight patients with FD were enrolled and underwent a crossover clinical trial with 2-week TEA at ST36 and PC6 and 2-week sham-TEA at nonacupuncture sham-points. Questionnaires were used to assess symptoms of dyspepsia and quality of life. Physiological testing included gastric emptying and electrogastrography. It was found that (1) TEA but not sham-TEA significantly improved dyspeptic symptoms and 4 domains in quality of life; improvement was also noted in self-rated anxiety and depression scores; (2) gastric emptying was significantly and substantially increased with 2-week TEA but not sham-TEA; and (3) gastric accommodation was also improved with TEA but not sham-TEA, reflected as increased ingested nutrient volumes at the levels of satiety and maximum tolerance. These findings suggest a therapeutic potential of self-administrated TEA method for functional dyspepsia, possibly attributed to improvement in gastric motility.

No MeSH data available.


Related in: MedlinePlus