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An alternative to current therapies of functional dyspepsia: self-administrated transcutaneous electroacupuncture improves dyspeptic symptoms.

Ji T, Li X, Lin L, Jiang L, Wang M, Zhou X, Zhang R, Chen JDz - Evid Based Complement Alternat Med (2014)

Bottom Line: Physiological testing included gastric emptying and electrogastrography.It was found that (1) TEA but not sham-TEA significantly improved dyspeptic symptoms and 4 domains in quality of life; improvement was also noted in self-rated anxiety and depression scores; (2) gastric emptying was significantly and substantially increased with 2-week TEA but not sham-TEA; and (3) gastric accommodation was also improved with TEA but not sham-TEA, reflected as increased ingested nutrient volumes at the levels of satiety and maximum tolerance.These findings suggest a therapeutic potential of self-administrated TEA method for functional dyspepsia, possibly attributed to improvement in gastric motility.

View Article: PubMed Central - PubMed

Affiliation: Division of Gastroenterology, Department of Gastroenterology, First Affiliated Hospital, Nanjing Medical University, Nanjing 210029, China.

ABSTRACT
Functional dyspepsia is of high prevalence with little treatment options. The aim of this study was to develop a new treatment method using self-management transcutaneous electroacupuncture (TEA) for functional dyspepsia (FD). Twenty-eight patients with FD were enrolled and underwent a crossover clinical trial with 2-week TEA at ST36 and PC6 and 2-week sham-TEA at nonacupuncture sham-points. Questionnaires were used to assess symptoms of dyspepsia and quality of life. Physiological testing included gastric emptying and electrogastrography. It was found that (1) TEA but not sham-TEA significantly improved dyspeptic symptoms and 4 domains in quality of life; improvement was also noted in self-rated anxiety and depression scores; (2) gastric emptying was significantly and substantially increased with 2-week TEA but not sham-TEA; and (3) gastric accommodation was also improved with TEA but not sham-TEA, reflected as increased ingested nutrient volumes at the levels of satiety and maximum tolerance. These findings suggest a therapeutic potential of self-administrated TEA method for functional dyspepsia, possibly attributed to improvement in gastric motility.

No MeSH data available.


Related in: MedlinePlus

Effects of TEA on gastric accommodation. TSV: threshold for satiety volume; MTV: maximum tolerance volume. **P < 0.01, versus before TEA; ***P < 0.001, versus before TEA.
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fig5: Effects of TEA on gastric accommodation. TSV: threshold for satiety volume; MTV: maximum tolerance volume. **P < 0.01, versus before TEA; ***P < 0.001, versus before TEA.

Mentions: There were significant differences between treatment groups in both ingested volumes for satiety and maximum tolerance (P = 0.0027, 0.0008, resp.) (Figure 5). Treatment group meant the patients who had took TEA treatment. Multiple comparisons showed a significant increase after the TEA treatment in both the ingested volume for satiety (267.5 ± 17.9 mL versus 336.6 ± 15.8 mL, P = 0.008) and the maximum tolerable volume (486.8 ± 30.3 mL versus 585.0 ± 20.4 mL, P < 0.001). The treatment of sham-TEA, however, did not yield such an increase.


An alternative to current therapies of functional dyspepsia: self-administrated transcutaneous electroacupuncture improves dyspeptic symptoms.

Ji T, Li X, Lin L, Jiang L, Wang M, Zhou X, Zhang R, Chen JDz - Evid Based Complement Alternat Med (2014)

Effects of TEA on gastric accommodation. TSV: threshold for satiety volume; MTV: maximum tolerance volume. **P < 0.01, versus before TEA; ***P < 0.001, versus before TEA.
© Copyright Policy - open-access
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC4230003&req=5

fig5: Effects of TEA on gastric accommodation. TSV: threshold for satiety volume; MTV: maximum tolerance volume. **P < 0.01, versus before TEA; ***P < 0.001, versus before TEA.
Mentions: There were significant differences between treatment groups in both ingested volumes for satiety and maximum tolerance (P = 0.0027, 0.0008, resp.) (Figure 5). Treatment group meant the patients who had took TEA treatment. Multiple comparisons showed a significant increase after the TEA treatment in both the ingested volume for satiety (267.5 ± 17.9 mL versus 336.6 ± 15.8 mL, P = 0.008) and the maximum tolerable volume (486.8 ± 30.3 mL versus 585.0 ± 20.4 mL, P < 0.001). The treatment of sham-TEA, however, did not yield such an increase.

Bottom Line: Physiological testing included gastric emptying and electrogastrography.It was found that (1) TEA but not sham-TEA significantly improved dyspeptic symptoms and 4 domains in quality of life; improvement was also noted in self-rated anxiety and depression scores; (2) gastric emptying was significantly and substantially increased with 2-week TEA but not sham-TEA; and (3) gastric accommodation was also improved with TEA but not sham-TEA, reflected as increased ingested nutrient volumes at the levels of satiety and maximum tolerance.These findings suggest a therapeutic potential of self-administrated TEA method for functional dyspepsia, possibly attributed to improvement in gastric motility.

View Article: PubMed Central - PubMed

Affiliation: Division of Gastroenterology, Department of Gastroenterology, First Affiliated Hospital, Nanjing Medical University, Nanjing 210029, China.

ABSTRACT
Functional dyspepsia is of high prevalence with little treatment options. The aim of this study was to develop a new treatment method using self-management transcutaneous electroacupuncture (TEA) for functional dyspepsia (FD). Twenty-eight patients with FD were enrolled and underwent a crossover clinical trial with 2-week TEA at ST36 and PC6 and 2-week sham-TEA at nonacupuncture sham-points. Questionnaires were used to assess symptoms of dyspepsia and quality of life. Physiological testing included gastric emptying and electrogastrography. It was found that (1) TEA but not sham-TEA significantly improved dyspeptic symptoms and 4 domains in quality of life; improvement was also noted in self-rated anxiety and depression scores; (2) gastric emptying was significantly and substantially increased with 2-week TEA but not sham-TEA; and (3) gastric accommodation was also improved with TEA but not sham-TEA, reflected as increased ingested nutrient volumes at the levels of satiety and maximum tolerance. These findings suggest a therapeutic potential of self-administrated TEA method for functional dyspepsia, possibly attributed to improvement in gastric motility.

No MeSH data available.


Related in: MedlinePlus