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An alternative to current therapies of functional dyspepsia: self-administrated transcutaneous electroacupuncture improves dyspeptic symptoms.

Ji T, Li X, Lin L, Jiang L, Wang M, Zhou X, Zhang R, Chen JDz - Evid Based Complement Alternat Med (2014)

Bottom Line: Physiological testing included gastric emptying and electrogastrography.It was found that (1) TEA but not sham-TEA significantly improved dyspeptic symptoms and 4 domains in quality of life; improvement was also noted in self-rated anxiety and depression scores; (2) gastric emptying was significantly and substantially increased with 2-week TEA but not sham-TEA; and (3) gastric accommodation was also improved with TEA but not sham-TEA, reflected as increased ingested nutrient volumes at the levels of satiety and maximum tolerance.These findings suggest a therapeutic potential of self-administrated TEA method for functional dyspepsia, possibly attributed to improvement in gastric motility.

View Article: PubMed Central - PubMed

Affiliation: Division of Gastroenterology, Department of Gastroenterology, First Affiliated Hospital, Nanjing Medical University, Nanjing 210029, China.

ABSTRACT
Functional dyspepsia is of high prevalence with little treatment options. The aim of this study was to develop a new treatment method using self-management transcutaneous electroacupuncture (TEA) for functional dyspepsia (FD). Twenty-eight patients with FD were enrolled and underwent a crossover clinical trial with 2-week TEA at ST36 and PC6 and 2-week sham-TEA at nonacupuncture sham-points. Questionnaires were used to assess symptoms of dyspepsia and quality of life. Physiological testing included gastric emptying and electrogastrography. It was found that (1) TEA but not sham-TEA significantly improved dyspeptic symptoms and 4 domains in quality of life; improvement was also noted in self-rated anxiety and depression scores; (2) gastric emptying was significantly and substantially increased with 2-week TEA but not sham-TEA; and (3) gastric accommodation was also improved with TEA but not sham-TEA, reflected as increased ingested nutrient volumes at the levels of satiety and maximum tolerance. These findings suggest a therapeutic potential of self-administrated TEA method for functional dyspepsia, possibly attributed to improvement in gastric motility.

No MeSH data available.


Related in: MedlinePlus

Effects of TEA on the percentage of normal gastric slow waves. **P < 0.01, versus before TEA.
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Related In: Results  -  Collection


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fig4: Effects of TEA on the percentage of normal gastric slow waves. **P < 0.01, versus before TEA.

Mentions: A significant difference was found between before and after TEA treatment in the percentage of normal gastric slow waves in both fasting and fed states (P = 0.0032 and 0.0001, resp.). It showed that after TEA treatment, the percentages of normal gastric slow waves in both fasting and fed states were higher than before. Then one-way ANOVA and multiple comparisons were performed for further authentication (Figure 4). In the effect of TEA on fasting slow waves, there was a significant difference between before TEA and TEA (71.2 ± 3.6% versus 82.0 ± 2.5%, P = 0.005). Significant difference was also found between before TEA and TEA (72.0 ± 2.9% versus 81.3 ± 2.9%, P = 0.008) on postprandial slow waves. However, sham-TEA did not show any significant effect on gastric slow waves.


An alternative to current therapies of functional dyspepsia: self-administrated transcutaneous electroacupuncture improves dyspeptic symptoms.

Ji T, Li X, Lin L, Jiang L, Wang M, Zhou X, Zhang R, Chen JDz - Evid Based Complement Alternat Med (2014)

Effects of TEA on the percentage of normal gastric slow waves. **P < 0.01, versus before TEA.
© Copyright Policy - open-access
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC4230003&req=5

fig4: Effects of TEA on the percentage of normal gastric slow waves. **P < 0.01, versus before TEA.
Mentions: A significant difference was found between before and after TEA treatment in the percentage of normal gastric slow waves in both fasting and fed states (P = 0.0032 and 0.0001, resp.). It showed that after TEA treatment, the percentages of normal gastric slow waves in both fasting and fed states were higher than before. Then one-way ANOVA and multiple comparisons were performed for further authentication (Figure 4). In the effect of TEA on fasting slow waves, there was a significant difference between before TEA and TEA (71.2 ± 3.6% versus 82.0 ± 2.5%, P = 0.005). Significant difference was also found between before TEA and TEA (72.0 ± 2.9% versus 81.3 ± 2.9%, P = 0.008) on postprandial slow waves. However, sham-TEA did not show any significant effect on gastric slow waves.

Bottom Line: Physiological testing included gastric emptying and electrogastrography.It was found that (1) TEA but not sham-TEA significantly improved dyspeptic symptoms and 4 domains in quality of life; improvement was also noted in self-rated anxiety and depression scores; (2) gastric emptying was significantly and substantially increased with 2-week TEA but not sham-TEA; and (3) gastric accommodation was also improved with TEA but not sham-TEA, reflected as increased ingested nutrient volumes at the levels of satiety and maximum tolerance.These findings suggest a therapeutic potential of self-administrated TEA method for functional dyspepsia, possibly attributed to improvement in gastric motility.

View Article: PubMed Central - PubMed

Affiliation: Division of Gastroenterology, Department of Gastroenterology, First Affiliated Hospital, Nanjing Medical University, Nanjing 210029, China.

ABSTRACT
Functional dyspepsia is of high prevalence with little treatment options. The aim of this study was to develop a new treatment method using self-management transcutaneous electroacupuncture (TEA) for functional dyspepsia (FD). Twenty-eight patients with FD were enrolled and underwent a crossover clinical trial with 2-week TEA at ST36 and PC6 and 2-week sham-TEA at nonacupuncture sham-points. Questionnaires were used to assess symptoms of dyspepsia and quality of life. Physiological testing included gastric emptying and electrogastrography. It was found that (1) TEA but not sham-TEA significantly improved dyspeptic symptoms and 4 domains in quality of life; improvement was also noted in self-rated anxiety and depression scores; (2) gastric emptying was significantly and substantially increased with 2-week TEA but not sham-TEA; and (3) gastric accommodation was also improved with TEA but not sham-TEA, reflected as increased ingested nutrient volumes at the levels of satiety and maximum tolerance. These findings suggest a therapeutic potential of self-administrated TEA method for functional dyspepsia, possibly attributed to improvement in gastric motility.

No MeSH data available.


Related in: MedlinePlus