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Scleredema adultorum of Buschke over an unusual site associated with pregnancy.

Vinod CS, Ambika H, Ambika H, Reddy N, Kumar De J - Indian Dermatol Online J (2014)

Bottom Line: Scleredema adultorum of Buschke is characterized by symmetrical, diffuse, non-pitting erythematous swelling of the skin due to accumulation of collagen and mucopolysaccharides in the dermis.Herein we report a case of scleredema over an unusual site in a pregnant woman.

View Article: PubMed Central - PubMed

Affiliation: Department of Dermatology, MVJ Medical College and Research Hospital, Bangalore, Karnataka, India.

ABSTRACT
Scleredema adultorum of Buschke is characterized by symmetrical, diffuse, non-pitting erythematous swelling of the skin due to accumulation of collagen and mucopolysaccharides in the dermis. Herein we report a case of scleredema over an unusual site in a pregnant woman.

No MeSH data available.


Related in: MedlinePlus

Medial aspect of thigh showing erythema and induration of skin
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Figure 2: Medial aspect of thigh showing erythema and induration of skin

Mentions: A 24-year-old full-term pregnant woman presented with diffuse swelling and thickening of the skin over the abdomen and thighs of 2 weeks duration. It started over the abdomen and slowly spread to the medial aspect of both thighs. It was associated with dull aching pain over the same sites. Patient gave a history of upper respiratory infection one week prior to onset of symptoms for which she was given a course of antibiotics. There was no history of fever, local rise of temperature, or past history of diabetes mellitus. On examination, her blood pressure was 110/70 mmHg; the skin over the lower abdomen, pubic area, and medial aspect of the both thighs showed a diffuse swelling with induration and peau d’orange appearance [Figures 1 and 2]. There was no pedal edema or edema of the vulva. Ophthalmic examination was within normal limits. Blood investigations showed hemoglobin 11.2 gm%, total count 8800/mm3, erythrocyte sedimentation rate 28 mm/hr, fasting blood sugar 82 g/dl, and postprandial blood sugar 128 g/dl. Liver and renal function tests were within normal limits. C-reactive protein and antistreptolysin O titer were elevated. Blood culture and throat swab culture showed no growth. Ultrasonography of the affected area showed thickening and hyperechogenicity of the skin and subcutaneous fat over the lower abdomen and medial aspect of thighs. Venous doppler of the involved area was unremarkable. Skin biopsy and histopathologic examination revealed mild thinning of the epidermis with thickening of the dermis. Deep dermis showed enlarged bundles of collagen separated by clear spaces causing fenestrations [Figure 3]. Alcian blue staining showed increased mucin and thickened collagen in the middle and deep dermis [Figure 4].


Scleredema adultorum of Buschke over an unusual site associated with pregnancy.

Vinod CS, Ambika H, Ambika H, Reddy N, Kumar De J - Indian Dermatol Online J (2014)

Medial aspect of thigh showing erythema and induration of skin
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4228642&req=5

Figure 2: Medial aspect of thigh showing erythema and induration of skin
Mentions: A 24-year-old full-term pregnant woman presented with diffuse swelling and thickening of the skin over the abdomen and thighs of 2 weeks duration. It started over the abdomen and slowly spread to the medial aspect of both thighs. It was associated with dull aching pain over the same sites. Patient gave a history of upper respiratory infection one week prior to onset of symptoms for which she was given a course of antibiotics. There was no history of fever, local rise of temperature, or past history of diabetes mellitus. On examination, her blood pressure was 110/70 mmHg; the skin over the lower abdomen, pubic area, and medial aspect of the both thighs showed a diffuse swelling with induration and peau d’orange appearance [Figures 1 and 2]. There was no pedal edema or edema of the vulva. Ophthalmic examination was within normal limits. Blood investigations showed hemoglobin 11.2 gm%, total count 8800/mm3, erythrocyte sedimentation rate 28 mm/hr, fasting blood sugar 82 g/dl, and postprandial blood sugar 128 g/dl. Liver and renal function tests were within normal limits. C-reactive protein and antistreptolysin O titer were elevated. Blood culture and throat swab culture showed no growth. Ultrasonography of the affected area showed thickening and hyperechogenicity of the skin and subcutaneous fat over the lower abdomen and medial aspect of thighs. Venous doppler of the involved area was unremarkable. Skin biopsy and histopathologic examination revealed mild thinning of the epidermis with thickening of the dermis. Deep dermis showed enlarged bundles of collagen separated by clear spaces causing fenestrations [Figure 3]. Alcian blue staining showed increased mucin and thickened collagen in the middle and deep dermis [Figure 4].

Bottom Line: Scleredema adultorum of Buschke is characterized by symmetrical, diffuse, non-pitting erythematous swelling of the skin due to accumulation of collagen and mucopolysaccharides in the dermis.Herein we report a case of scleredema over an unusual site in a pregnant woman.

View Article: PubMed Central - PubMed

Affiliation: Department of Dermatology, MVJ Medical College and Research Hospital, Bangalore, Karnataka, India.

ABSTRACT
Scleredema adultorum of Buschke is characterized by symmetrical, diffuse, non-pitting erythematous swelling of the skin due to accumulation of collagen and mucopolysaccharides in the dermis. Herein we report a case of scleredema over an unusual site in a pregnant woman.

No MeSH data available.


Related in: MedlinePlus