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A clinico-histopathological study of lupus vulgaris: A 3 year experience at a tertiary care centre.

Pai VV, Naveen KN, Athanikar SB, Dinesh US, Divyashree A, Gupta G - Indian Dermatol Online J (2014)

Bottom Line: Lupus vulgaris is the most common form of cutaneous tuberculosis in adults.Fourteen cases of lupus vulgaris cases reported during the study period with eaqual incidence among males and females.Histopathologically tubercular granulomas were seen in all cases as compared to other studies.

View Article: PubMed Central - PubMed

Affiliation: Department of Dermatology, Goa Medical College, Bambolim, India.

ABSTRACT

Background: Lupus vulgaris is the most common form of cutaneous tuberculosis in adults. Lupus vulgaris is caused by hematogenous, lymphatic, or contiguous spread from elsewhere in the body. histologically it is charecterised by typical tubercles with or without caseation, surrounded by epitheloid histiocytes and multinucleate giant cells in the superficial epidermis with prominent peripheral lymphocytes.

Materials and method: All cases of clinically and histopathologicaly diagnosed lupus vulgaris over the previous five years were included in the study.

Results: Fourteen cases of lupus vulgaris cases reported during the study period with eaqual incidence among males and females.

Discussion: Plaque type of lupus vulgaris was the most common type. Histopathologically tubercular granulomas were seen in all cases as compared to other studies.

Conclusion: Different patterns of lupus vulgaris are reported.

No MeSH data available.


Related in: MedlinePlus

Section shows epidermis with marked acanthosis and neutrophilic abcess mixed with debris in keratin layers. The papillary dermis shows epitheliod cell granuloma with multinucleated gaint cell. The granuloma are surrounded by plasma cells and lymphocytes. Few eosinophils are seen amidst chronic inflammatory cell infiltrate. H and E, ×40
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Figure 14: Section shows epidermis with marked acanthosis and neutrophilic abcess mixed with debris in keratin layers. The papillary dermis shows epitheliod cell granuloma with multinucleated gaint cell. The granuloma are surrounded by plasma cells and lymphocytes. Few eosinophils are seen amidst chronic inflammatory cell infiltrate. H and E, ×40


A clinico-histopathological study of lupus vulgaris: A 3 year experience at a tertiary care centre.

Pai VV, Naveen KN, Athanikar SB, Dinesh US, Divyashree A, Gupta G - Indian Dermatol Online J (2014)

Section shows epidermis with marked acanthosis and neutrophilic abcess mixed with debris in keratin layers. The papillary dermis shows epitheliod cell granuloma with multinucleated gaint cell. The granuloma are surrounded by plasma cells and lymphocytes. Few eosinophils are seen amidst chronic inflammatory cell infiltrate. H and E, ×40
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4228641&req=5

Figure 14: Section shows epidermis with marked acanthosis and neutrophilic abcess mixed with debris in keratin layers. The papillary dermis shows epitheliod cell granuloma with multinucleated gaint cell. The granuloma are surrounded by plasma cells and lymphocytes. Few eosinophils are seen amidst chronic inflammatory cell infiltrate. H and E, ×40
Bottom Line: Lupus vulgaris is the most common form of cutaneous tuberculosis in adults.Fourteen cases of lupus vulgaris cases reported during the study period with eaqual incidence among males and females.Histopathologically tubercular granulomas were seen in all cases as compared to other studies.

View Article: PubMed Central - PubMed

Affiliation: Department of Dermatology, Goa Medical College, Bambolim, India.

ABSTRACT

Background: Lupus vulgaris is the most common form of cutaneous tuberculosis in adults. Lupus vulgaris is caused by hematogenous, lymphatic, or contiguous spread from elsewhere in the body. histologically it is charecterised by typical tubercles with or without caseation, surrounded by epitheloid histiocytes and multinucleate giant cells in the superficial epidermis with prominent peripheral lymphocytes.

Materials and method: All cases of clinically and histopathologicaly diagnosed lupus vulgaris over the previous five years were included in the study.

Results: Fourteen cases of lupus vulgaris cases reported during the study period with eaqual incidence among males and females.

Discussion: Plaque type of lupus vulgaris was the most common type. Histopathologically tubercular granulomas were seen in all cases as compared to other studies.

Conclusion: Different patterns of lupus vulgaris are reported.

No MeSH data available.


Related in: MedlinePlus