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Effect of a single session of transcranial direct-current stimulation on balance and spatiotemporal gait variables in children with cerebral palsy: A randomized sham-controlled study.

Grecco LA, Duarte NA, Zanon N, Galli M, Fregni F, Oliveira CS - Braz J Phys Ther (2014)

Bottom Line: Significant reductions were found in the experimental group regarding oscillations during standing in the anteroposterior and mediolateral directions with eyes open and eyes closed in comparison with the control group (p<0.05).In the intra-group analysis, the experimental group exhibited significant improvements in gait velocity, cadence, and oscillation in the center of pressure during standing (p<0.05).No significant differences were found in the control group among the different evaluations.

View Article: PubMed Central - PubMed

Affiliation: Universidade Nove de Julho, São Paulo, SP, Brazil.

ABSTRACT

Background: Transcranial direct-current stimulation (tDCS) has been widely studied with the aim of enhancing local synaptic efficacy and modulating the electrical activity of the cortex in patients with neurological disorders.

Objective: The purpose of the present study was to determine the effect of a single session of tDCS regarding immediate changes in spatiotemporal gait and oscillations of the center of pressure (30 seconds) in children with cerebral palsy (CP).

Method: A randomized controlled trial with a blinded evaluator was conducted involving 20 children with CP between six and ten years of age. Gait and balance were evaluated three times: Evaluation 1 (before the stimulation), Evaluation 2 (immediately after stimulation), and Evaluation 3 (20 minutes after the stimulation). The protocol consisted of a 20-minute session of tDCS applied to the primary motor cortex at an intensity of 1 mA. The participants were randomly allocated to two groups: experimental group - anodal stimulation of the primary motor cortex; and control group - placebo transcranial stimulation.

Results: Significant reductions were found in the experimental group regarding oscillations during standing in the anteroposterior and mediolateral directions with eyes open and eyes closed in comparison with the control group (p<0.05). In the intra-group analysis, the experimental group exhibited significant improvements in gait velocity, cadence, and oscillation in the center of pressure during standing (p<0.05). No significant differences were found in the control group among the different evaluations.

Conclusion: A single session of tDCS applied to the primary motor cortex promotes positive changes in static balance and gait velocity in children with cerebral palsy.

No MeSH data available.


Related in: MedlinePlus

Flow diagram of study based on the Consolidated Standards of ReportingTrials (CONSORT) Statement.
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f01: Flow diagram of study based on the Consolidated Standards of ReportingTrials (CONSORT) Statement.

Mentions: The present randomized, sham-controlled, cross-sectional study (Figure 1) was carried out in compliance with the ethical standardsof the Declaration of Helsinki and received approval from the Human Research EthicsCommittee of Universidade Nove de Julho (UNINOVE), São Paulo, SP,Brazil, under process number 69803/2012. This study is registered with the BrazilianRegistry of Clinical Trials (process RBR-9B5DH7). All guardians signed a statement ofinformed consent agreeing to the participation of their children.


Effect of a single session of transcranial direct-current stimulation on balance and spatiotemporal gait variables in children with cerebral palsy: A randomized sham-controlled study.

Grecco LA, Duarte NA, Zanon N, Galli M, Fregni F, Oliveira CS - Braz J Phys Ther (2014)

Flow diagram of study based on the Consolidated Standards of ReportingTrials (CONSORT) Statement.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4228627&req=5

f01: Flow diagram of study based on the Consolidated Standards of ReportingTrials (CONSORT) Statement.
Mentions: The present randomized, sham-controlled, cross-sectional study (Figure 1) was carried out in compliance with the ethical standardsof the Declaration of Helsinki and received approval from the Human Research EthicsCommittee of Universidade Nove de Julho (UNINOVE), São Paulo, SP,Brazil, under process number 69803/2012. This study is registered with the BrazilianRegistry of Clinical Trials (process RBR-9B5DH7). All guardians signed a statement ofinformed consent agreeing to the participation of their children.

Bottom Line: Significant reductions were found in the experimental group regarding oscillations during standing in the anteroposterior and mediolateral directions with eyes open and eyes closed in comparison with the control group (p<0.05).In the intra-group analysis, the experimental group exhibited significant improvements in gait velocity, cadence, and oscillation in the center of pressure during standing (p<0.05).No significant differences were found in the control group among the different evaluations.

View Article: PubMed Central - PubMed

Affiliation: Universidade Nove de Julho, São Paulo, SP, Brazil.

ABSTRACT

Background: Transcranial direct-current stimulation (tDCS) has been widely studied with the aim of enhancing local synaptic efficacy and modulating the electrical activity of the cortex in patients with neurological disorders.

Objective: The purpose of the present study was to determine the effect of a single session of tDCS regarding immediate changes in spatiotemporal gait and oscillations of the center of pressure (30 seconds) in children with cerebral palsy (CP).

Method: A randomized controlled trial with a blinded evaluator was conducted involving 20 children with CP between six and ten years of age. Gait and balance were evaluated three times: Evaluation 1 (before the stimulation), Evaluation 2 (immediately after stimulation), and Evaluation 3 (20 minutes after the stimulation). The protocol consisted of a 20-minute session of tDCS applied to the primary motor cortex at an intensity of 1 mA. The participants were randomly allocated to two groups: experimental group - anodal stimulation of the primary motor cortex; and control group - placebo transcranial stimulation.

Results: Significant reductions were found in the experimental group regarding oscillations during standing in the anteroposterior and mediolateral directions with eyes open and eyes closed in comparison with the control group (p<0.05). In the intra-group analysis, the experimental group exhibited significant improvements in gait velocity, cadence, and oscillation in the center of pressure during standing (p<0.05). No significant differences were found in the control group among the different evaluations.

Conclusion: A single session of tDCS applied to the primary motor cortex promotes positive changes in static balance and gait velocity in children with cerebral palsy.

No MeSH data available.


Related in: MedlinePlus