Limits...
Low-magnitude high-frequency loading, by whole-body vibration, accelerates early implant osseointegration in ovariectomized rats.

Liang YQ, Qi MC, Xu J, Xu J, Liu HW, Dong W, Li JY, Hu M - Mol Med Rep (2014)

Bottom Line: LMHF loading via whole‑body vibration (WBV) for 8 weeks has previously been demonstrated to significantly enhance bone‑to‑implant contact, peri‑implant bone fraction and implant mechanical properties in osteoporotic rats.In the present study, LMHF loading by WBV was performed in osteoporotic rats, with a loading duration of 4 weeks during the early stages of bone healing.The results indicated that 4‑week LMHF loading by WBV partly reversed the negative effects of osteoporosis and accelerated early peri‑implant osseointegration in ovariectomized rats.

View Article: PubMed Central - PubMed

Affiliation: Department of Stomatology, Chinese PLA General Hospital, Beijing 100853, P.R. China.

ABSTRACT
Osteoporosis deteriorates jaw bone quality and may compromise early implant osseointegration and early implant loading. The influence of low‑magnitude, high‑frequency (LMHF) vibration on peri‑implant bone healing and implant integration in osteoporotic bones remains poorly understood. LMHF loading via whole‑body vibration (WBV) for 8 weeks has previously been demonstrated to significantly enhance bone‑to‑implant contact, peri‑implant bone fraction and implant mechanical properties in osteoporotic rats. In the present study, LMHF loading by WBV was performed in osteoporotic rats, with a loading duration of 4 weeks during the early stages of bone healing. The results indicated that 4‑week LMHF loading by WBV partly reversed the negative effects of osteoporosis and accelerated early peri‑implant osseointegration in ovariectomized rats.

Show MeSH

Related in: MedlinePlus

Region of interest for evaluation of BV/TV. The area is defined as a rectangular region within 2 mm from the axis of the implant.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
getmorefigures.php?uid=PMC4227418&req=5

f2-mmr-10-06-2835: Region of interest for evaluation of BV/TV. The area is defined as a rectangular region within 2 mm from the axis of the implant.

Mentions: Histomorphometric analysis was performed with a semi-automated digitizing image analyzer system, consisting of an Eclipse E600 stereoscopic microscope, a computer-coupled Digital Eclipse DXM 1200 digital camera and NIS-Elements F 2.20 imaging software (Nikon Corporation, Tokyo, Japan) (2). Bone static indices included the following: Bone-to-implant contact (BIC, %) = summation of the lengths of direct bone-to-implant contact interface/the length of total implant surface; peri-implant bone fraction (BF, %) = the percentage area of the bone within the rectangular region 2.0 mm from the axis of the implant; and thickness of the bone lamellae (TBL, μm) in direct contact with the implant at cancellous bone area (Fig. 2). For evaluation of the TBL, five equally distributed sites were chosen for each screw and the mean value of all screws was accepted as the value of the index of the section (7). Three discontinuous sections of each specimen were measured at a magnification of ×100 and the mean of the three sections was accepted as the value of the specimen for each index.


Low-magnitude high-frequency loading, by whole-body vibration, accelerates early implant osseointegration in ovariectomized rats.

Liang YQ, Qi MC, Xu J, Xu J, Liu HW, Dong W, Li JY, Hu M - Mol Med Rep (2014)

Region of interest for evaluation of BV/TV. The area is defined as a rectangular region within 2 mm from the axis of the implant.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4227418&req=5

f2-mmr-10-06-2835: Region of interest for evaluation of BV/TV. The area is defined as a rectangular region within 2 mm from the axis of the implant.
Mentions: Histomorphometric analysis was performed with a semi-automated digitizing image analyzer system, consisting of an Eclipse E600 stereoscopic microscope, a computer-coupled Digital Eclipse DXM 1200 digital camera and NIS-Elements F 2.20 imaging software (Nikon Corporation, Tokyo, Japan) (2). Bone static indices included the following: Bone-to-implant contact (BIC, %) = summation of the lengths of direct bone-to-implant contact interface/the length of total implant surface; peri-implant bone fraction (BF, %) = the percentage area of the bone within the rectangular region 2.0 mm from the axis of the implant; and thickness of the bone lamellae (TBL, μm) in direct contact with the implant at cancellous bone area (Fig. 2). For evaluation of the TBL, five equally distributed sites were chosen for each screw and the mean value of all screws was accepted as the value of the index of the section (7). Three discontinuous sections of each specimen were measured at a magnification of ×100 and the mean of the three sections was accepted as the value of the specimen for each index.

Bottom Line: LMHF loading via whole‑body vibration (WBV) for 8 weeks has previously been demonstrated to significantly enhance bone‑to‑implant contact, peri‑implant bone fraction and implant mechanical properties in osteoporotic rats.In the present study, LMHF loading by WBV was performed in osteoporotic rats, with a loading duration of 4 weeks during the early stages of bone healing.The results indicated that 4‑week LMHF loading by WBV partly reversed the negative effects of osteoporosis and accelerated early peri‑implant osseointegration in ovariectomized rats.

View Article: PubMed Central - PubMed

Affiliation: Department of Stomatology, Chinese PLA General Hospital, Beijing 100853, P.R. China.

ABSTRACT
Osteoporosis deteriorates jaw bone quality and may compromise early implant osseointegration and early implant loading. The influence of low‑magnitude, high‑frequency (LMHF) vibration on peri‑implant bone healing and implant integration in osteoporotic bones remains poorly understood. LMHF loading via whole‑body vibration (WBV) for 8 weeks has previously been demonstrated to significantly enhance bone‑to‑implant contact, peri‑implant bone fraction and implant mechanical properties in osteoporotic rats. In the present study, LMHF loading by WBV was performed in osteoporotic rats, with a loading duration of 4 weeks during the early stages of bone healing. The results indicated that 4‑week LMHF loading by WBV partly reversed the negative effects of osteoporosis and accelerated early peri‑implant osseointegration in ovariectomized rats.

Show MeSH
Related in: MedlinePlus