Kidney function in severely obese adolescents undergoing bariatric surgery.
Bottom Line: Determine objective measures of kidney function and analyze factors associated with kidney dysfunction in severely obese adolescents undergoing weight loss surgery were described.A significant number of severely obese adolescents undergoing weight loss surgery have evidence of early kidney dysfunction.Longitudinal studies following weight loss surgery in these individuals are needed to determine whether these kidney abnormalities are reversible following weight loss therapy.
Affiliation: Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.Show MeSH
Related in: MedlinePlus
Mentions: The mean cystatin C-based eGFR was 107.6 ml/min/1.73m2. Most of the Teen-LABS participants (68.5%) had a normal eGFR (90–150 ml/min/1.73m2) However, 51 (21.4%) had an eGFR of 60–90 ml/min/1.73m2; 7 (3.0%) had an eGFR <60 ml/min/1.73m2; and 17 (7.1%) had an eGFR >150 ml/min/1.73m2. Percentile distribution of eGFR from the Teen-LABS cohort and from published NHANES data is shown in Figure 1. There were more subjects in low percentile and high percentile brackets in the Teen-LABS cohort than in the NHANES participants.14
Affiliation: Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.