Bee venom acupuncture for rheumatoid arthritis: a systematic review of randomised clinical trials.
Bottom Line: BVA involved injecting purified, diluted BV into acupoints.A total of 304 potentially relevant studies were identified; only one RCT met our inclusion criteria.Compared with placebo, BVA may more effectively improve joint pain, swollen joint counts, tender joint counts, ESR and CRP but was not shown to improve morning stiffness.
Affiliation: Medical Research Division, Korea Institute of Oriental Medicine, Daejeon, South Korea.Show MeSH
Related in: MedlinePlus
Mentions: The search generated a total of 304 hits, of which only one met our inclusion criteria (figure 1). Thirteen RCTs were among the excluded articles for the following reasons: four RCTs, which were conducted in China, were excluded because the BVA was not made with purified, diluted BV but with live bee stings (see online supplements 2 and 3),21–24 four RCTs employed herbal medicine as coadministrator,25–28 two RCTs included herbal medicine as control treatment,2930 one RCT compared two different acupoints,31 one RCT was not related to RA32 and one RCT was a duplicated publication.33 The key data from the eligible RCT are summarised in table 1. This trial was conducted in Korea.34
Affiliation: Medical Research Division, Korea Institute of Oriental Medicine, Daejeon, South Korea.