Introducing the non-invasive prenatal test for trisomy 21 in Belgium: a cost-consequences analysis.
Bottom Line: A cost-consequences analysis was performed presenting the impact on benefits, harms and costs.Introducing NIPT in the first or second line reduces harm by decreasing the number of procedure-related miscarriages after invasive testing.In Belgium, the introduction and reimbursement of NIPT as a second line triage test significantly reduces procedure-related miscarriages without increasing the short-term screening costs.
Affiliation: Belgian Health Care Knowledge Centre (KCE), Brussels, Belgium.Show MeSH
Related in: MedlinePlus
Mentions: Figure 2 provides an overview of the most relevant scenarios, including the impact of uncertainty of all input variables. The x-axis and y-axis represent the number of T21 diagnoses and total short-term costs, respectively. We remark that these are not the only outcomes of importance. Other outcomes, such as the number of procedure-related miscarriages, should also be taken into consideration. Further details on all outcomes are mentioned in online supplementary tables.
Affiliation: Belgian Health Care Knowledge Centre (KCE), Brussels, Belgium.