National and regional estimates of term and preterm babies born small for gestational age in 138 low-income and middle-income countries in 2010.
Bottom Line: Most small-for-gestational-age infants were born in India, Pakistan, Nigeria, and Bangladesh.Implementation of effective interventions for babies born too small or too soon is an urgent priority to increase survival and reduce disability, stunting, and non-communicable diseases.Bill & Melinda Gates Foundation by a grant to the US Fund for UNICEF to support the activities of the Child Health Epidemiology Reference Group (CHERG).
Affiliation: Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA; Department of Newborn Medicine, Brigham and Women's Hospital, Boston, MA, USA. Electronic address: firstname.lastname@example.org.Show MeSH
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Mentions: The appendix shows data inputs for the estimation process (p 12), study characteristics of the 22 CHERG cohorts included in our study13,17–36 (pp 2–4), and survey characteristics for the WHO datasets9 (p 6). From the literature review, we identified six studies reporting prevalence of babies born small for gestational age and the proportion of low-birthweight infants (appendix p 5); however, none of these studies could be used because term-SGA or preterm-SGA rates were not reported. Table 1 shows the final model for term-SGA. Logit(term-SGA prevalence) increased with rising rates of low birthweight and neonatal mortality (figure 1). Regional random effects were applied to account for regional variations of the relations. With low birthweight and neonatal mortality included in the model, socioeconomic covariates were not significant and, thus, not retained in the final model. Data source covariates were retained to control for selection bias and data quality. Regression diagnostic plots are shown in the appendix (p 13); the overall model fit was good (adjusted R2 0·8237).
Affiliation: Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA; Department of Newborn Medicine, Brigham and Women's Hospital, Boston, MA, USA. Electronic address: email@example.com.