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The scientific achievements of the decades in Korean Acute Myocardial Infarction Registry.

Kim HK, Jeong MH, Lee SH, Sim DS, Hong YJ, Ahn Y, Kim CJ, Cho MC, Kim YJ - Korean J. Intern. Med. (2014)

Bottom Line: Triple antiplatelet therapy, consisting of aspirin, clopidogrel and cilostazol, was effective at preventing major adverse clinical outcomes.Drug-eluting stents were effective and safe in AMI patients with no increased risk of stent thrombosis.Statin therapy was effective in Korean AMI patients, including those with very low levels of low density cholesterol.

View Article: PubMed Central - PubMed

Affiliation: The Heart Center, Chonnam National University Hospital, Gwangju, Korea.

ABSTRACT
The Korea Acute Myocardial Infarction Registry (KAMIR) was the first nationwide registry data collection designed to track outcomes of patients with acute myocardial infarction (AMI). These studies reflect the current therapeutic approaches and management for AMI in Korea. The results of KAMIR could help clinicians to predict the prognosis of their patients and identify better diagnostic and treatment tools to improve the quality of care. The KAMIR score was proposed to be a predictor of the prognosis of AMI patients. Triple antiplatelet therapy, consisting of aspirin, clopidogrel and cilostazol, was effective at preventing major adverse clinical outcomes. Drug-eluting stents were effective and safe in AMI patients with no increased risk of stent thrombosis. Statin therapy was effective in Korean AMI patients, including those with very low levels of low density cholesterol. The present review summarizes the 10-year scientific achievements of KAMIR from admission to outpatient care during long-term clinical follow-up.

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Related in: MedlinePlus

Major adverse cardiac events according to statin use in patients with very low low-density lipoprotein cholesterol levels. MACE, major adverse clinical events; PCI, percutaneous coronary intervention.
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Figure 2: Major adverse cardiac events according to statin use in patients with very low low-density lipoprotein cholesterol levels. MACE, major adverse clinical events; PCI, percutaneous coronary intervention.

Mentions: The optimal medical therapy after discharge was prescribed at suboptimal rates, particularly in high-risk AMI patients [58,59]. Early and continuous statin therapy improved the prognosis after AMI [60]. Lifesaving medications, including lipid-lowering drugs, were underused in patients with lower low-density lipoprotein cholesterol (LDL-C) levels. More intensive treatments, including lipid-lowering therapy, for AMI in patients with lower LDL-C level might improve clinical outcomes [61]. Statin therapy in patients with LDL-C levels < 70 mg/dL was also associated with improved clinical outcomes (Fig. 2) [62]. Stent thrombosis could be reduced by statins in AMI patients with levels of high C-reactive protein [63]. Statins were also effective in patients with renal dysfunction [64].


The scientific achievements of the decades in Korean Acute Myocardial Infarction Registry.

Kim HK, Jeong MH, Lee SH, Sim DS, Hong YJ, Ahn Y, Kim CJ, Cho MC, Kim YJ - Korean J. Intern. Med. (2014)

Major adverse cardiac events according to statin use in patients with very low low-density lipoprotein cholesterol levels. MACE, major adverse clinical events; PCI, percutaneous coronary intervention.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4219958&req=5

Figure 2: Major adverse cardiac events according to statin use in patients with very low low-density lipoprotein cholesterol levels. MACE, major adverse clinical events; PCI, percutaneous coronary intervention.
Mentions: The optimal medical therapy after discharge was prescribed at suboptimal rates, particularly in high-risk AMI patients [58,59]. Early and continuous statin therapy improved the prognosis after AMI [60]. Lifesaving medications, including lipid-lowering drugs, were underused in patients with lower low-density lipoprotein cholesterol (LDL-C) levels. More intensive treatments, including lipid-lowering therapy, for AMI in patients with lower LDL-C level might improve clinical outcomes [61]. Statin therapy in patients with LDL-C levels < 70 mg/dL was also associated with improved clinical outcomes (Fig. 2) [62]. Stent thrombosis could be reduced by statins in AMI patients with levels of high C-reactive protein [63]. Statins were also effective in patients with renal dysfunction [64].

Bottom Line: Triple antiplatelet therapy, consisting of aspirin, clopidogrel and cilostazol, was effective at preventing major adverse clinical outcomes.Drug-eluting stents were effective and safe in AMI patients with no increased risk of stent thrombosis.Statin therapy was effective in Korean AMI patients, including those with very low levels of low density cholesterol.

View Article: PubMed Central - PubMed

Affiliation: The Heart Center, Chonnam National University Hospital, Gwangju, Korea.

ABSTRACT
The Korea Acute Myocardial Infarction Registry (KAMIR) was the first nationwide registry data collection designed to track outcomes of patients with acute myocardial infarction (AMI). These studies reflect the current therapeutic approaches and management for AMI in Korea. The results of KAMIR could help clinicians to predict the prognosis of their patients and identify better diagnostic and treatment tools to improve the quality of care. The KAMIR score was proposed to be a predictor of the prognosis of AMI patients. Triple antiplatelet therapy, consisting of aspirin, clopidogrel and cilostazol, was effective at preventing major adverse clinical outcomes. Drug-eluting stents were effective and safe in AMI patients with no increased risk of stent thrombosis. Statin therapy was effective in Korean AMI patients, including those with very low levels of low density cholesterol. The present review summarizes the 10-year scientific achievements of KAMIR from admission to outpatient care during long-term clinical follow-up.

Show MeSH
Related in: MedlinePlus