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Extra-axial medulloblastoma in cerebello-pontine angle: A report of a rare case with literature review.

Bahrami E, Bakhti S, Fereshtehnejad SM, Parvaresh M, Khani MR - Med J Islam Repub Iran (2014)

Bottom Line: In this report, a 23-year-old male patient with a two month history of deafness, nausea, vomiting and ataxia is presented.Clinical and radiological findings demonstrated a heterogeneously enhanced extra-axial lesion in the right CP angle.After surgery, the patient had no neurological deficit and the audiometric findings were improved.

View Article: PubMed Central - HTML - PubMed

Affiliation: 1. Department of Neurosurgery, Rasool-e-Akram Hospital, Iran University of Medical Sciences, Tehran, Iran. bahrami_eses@yahoo.com.

ABSTRACT
Medulloblastoma is quite uncommon in the adult population and even rarer in extra-axial site in cerebello-pontine (CP) angle. In this report, a 23-year-old male patient with a two month history of deafness, nausea, vomiting and ataxia is presented. Clinical and radiological findings demonstrated a heterogeneously enhanced extra-axial lesion in the right CP angle. Total excision was performed and the histopathological features of medulloblastoma were confirmed. After surgery, the patient had no neurological deficit and the audiometric findings were improved. In addition, he underwent adjuant radiotherapy and no sign of metastatic mass was observed in follow-up spinal cord MRI. Although extremely rare, medulloblastoma must be considered in the differential diagnosis of extra-axial CP angle lesions.

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Mentions: A 23 year old man presented with a two month history of deafness of the right ear followed by nausea, vomiting and ataxia. Neurological examination yielded normal findings, except for audiometric examination that showed hearing loss and ataxic gait. In particular, audiometric assessment demonstrated a discrete sensorineural hearing loss of 50 dB at 1 KHz to 8 KHz. Magnetic resonance imaging (MRI) revealed a cystic and necrotic lesion in the right CP angle. The lesion was heterogenously more hypointense on T1 and hyperintense on T2 (Fig. 1). The lesion enhanced on T1 weighted MRI images after injection of gadolinium (Fig. 2). Spinal cord MRI did not reveal any evidence of metastasis.


Extra-axial medulloblastoma in cerebello-pontine angle: A report of a rare case with literature review.

Bahrami E, Bakhti S, Fereshtehnejad SM, Parvaresh M, Khani MR - Med J Islam Repub Iran (2014)

© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4219907&req=5

Mentions: A 23 year old man presented with a two month history of deafness of the right ear followed by nausea, vomiting and ataxia. Neurological examination yielded normal findings, except for audiometric examination that showed hearing loss and ataxic gait. In particular, audiometric assessment demonstrated a discrete sensorineural hearing loss of 50 dB at 1 KHz to 8 KHz. Magnetic resonance imaging (MRI) revealed a cystic and necrotic lesion in the right CP angle. The lesion was heterogenously more hypointense on T1 and hyperintense on T2 (Fig. 1). The lesion enhanced on T1 weighted MRI images after injection of gadolinium (Fig. 2). Spinal cord MRI did not reveal any evidence of metastasis.

Bottom Line: In this report, a 23-year-old male patient with a two month history of deafness, nausea, vomiting and ataxia is presented.Clinical and radiological findings demonstrated a heterogeneously enhanced extra-axial lesion in the right CP angle.After surgery, the patient had no neurological deficit and the audiometric findings were improved.

View Article: PubMed Central - HTML - PubMed

Affiliation: 1. Department of Neurosurgery, Rasool-e-Akram Hospital, Iran University of Medical Sciences, Tehran, Iran. bahrami_eses@yahoo.com.

ABSTRACT
Medulloblastoma is quite uncommon in the adult population and even rarer in extra-axial site in cerebello-pontine (CP) angle. In this report, a 23-year-old male patient with a two month history of deafness, nausea, vomiting and ataxia is presented. Clinical and radiological findings demonstrated a heterogeneously enhanced extra-axial lesion in the right CP angle. Total excision was performed and the histopathological features of medulloblastoma were confirmed. After surgery, the patient had no neurological deficit and the audiometric findings were improved. In addition, he underwent adjuant radiotherapy and no sign of metastatic mass was observed in follow-up spinal cord MRI. Although extremely rare, medulloblastoma must be considered in the differential diagnosis of extra-axial CP angle lesions.

No MeSH data available.


Related in: MedlinePlus