|
Validity of current electrodiagnostic techniques in the diagnosis of carpal tunnel syndrome.
Bottom Line:
Eighty five patients with clinical diagnosis of CTS were compared with the same number of healthy people.Sensitivity of Two-segment method was 98.8% and mixed palmwrist median Nerve Conduction Velocity (NCV) study showed a sensitivity and specificity of 97.6%, 83.5% respectively.Radial-median latency difference study (optimal cut-off point ≥0.5) and study of wrist-segment NCV (optimal cut-off point <50.45) were the most valuable techniques in diagnosis of CTS, respectively.
Affiliation: 1. MD, Physical Medicine and Rehabilitation Research Center, Tabriz University of Medical Sciences, Tabriz, Iran. binasadat@yahoo.com.
ABSTRACT
Background: Determining the validity of current median sensory nerve conduction techniques for diagnosis of carpal tunnel syndrome (CTS). Methods: Eighty five patients with clinical diagnosis of CTS were compared with the same number of healthy people. The validity of electrodiagnostic tests were compared in a case-control manner. These electrodiagnostic techniques included long-segment, short-segment, 2-segment and relative slowing studies; as well as distoproximal ratio. Receiver Operating Characteristic (ROC) curve employed for comparison, determining the optimal cut-off points for each test. Validity was evaluated with likelihood ratio. Results: Likelihood ratio (LHR) for Radial-median sensory latency difference was ∞, while LHR for ulnarmedian sensory latency difference was 16.9. Sensitivity of Two-segment method was 98.8% and mixed palmwrist median Nerve Conduction Velocity (NCV) study showed a sensitivity and specificity of 97.6%, 83.5% respectively. Conclusions: Radial-median latency difference study (optimal cut-off point ≥0.5) and study of wrist-segment NCV (optimal cut-off point <50.45) were the most valuable techniques in diagnosis of CTS, respectively. Median-ulnar latency difference study and disto-proximal ratio study had more diagnostic implication than long and short (mixed) segment technique in this regard. No MeSH data available. Related in: MedlinePlus |
Related In:
Results -
Collection
License getmorefigures.php?uid=PMC4219876&req=5
Mentions: Figure 1 and 2 express the ROC diagrams of different techniques. The higher the AUC, the greater was the accuracy of the measurement. Therefore, two-segment values had the highest accuracy rate for diagnosis of CTS. |
View Article: PubMed Central - HTML - PubMed
Affiliation: 1. MD, Physical Medicine and Rehabilitation Research Center, Tabriz University of Medical Sciences, Tabriz, Iran. binasadat@yahoo.com.
Background: Determining the validity of current median sensory nerve conduction techniques for diagnosis of carpal tunnel syndrome (CTS).
Methods: Eighty five patients with clinical diagnosis of CTS were compared with the same number of healthy people. The validity of electrodiagnostic tests were compared in a case-control manner. These electrodiagnostic techniques included long-segment, short-segment, 2-segment and relative slowing studies; as well as distoproximal ratio. Receiver Operating Characteristic (ROC) curve employed for comparison, determining the optimal cut-off points for each test. Validity was evaluated with likelihood ratio.
Results: Likelihood ratio (LHR) for Radial-median sensory latency difference was ∞, while LHR for ulnarmedian sensory latency difference was 16.9. Sensitivity of Two-segment method was 98.8% and mixed palmwrist median Nerve Conduction Velocity (NCV) study showed a sensitivity and specificity of 97.6%, 83.5% respectively.
Conclusions: Radial-median latency difference study (optimal cut-off point ≥0.5) and study of wrist-segment NCV (optimal cut-off point <50.45) were the most valuable techniques in diagnosis of CTS, respectively. Median-ulnar latency difference study and disto-proximal ratio study had more diagnostic implication than long and short (mixed) segment technique in this regard.
No MeSH data available.
