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Association between smoking status and the parameters of vascular structure and function in adults: results from the EVIDENT study.

Recio-Rodriguez JI, Gomez-Marcos MA, Patino Alonso MC, Martin-Cantera C, Ibañez-Jalon E, Melguizo-Bejar A, Garcia-Ortiz L, EVIDENT Gro - BMC Cardiovasc Disord (2013)

Bottom Line: After controlling for the effect of age, sex and other risk factors, present smokers have higher values of carotid intima-media thickness (p = 0.011).Along the same lines, current smokers have higher values of pulse wave velocity and lower mean values of ankle-brachial index but without statistical significance in both cases.Among the parameters of vascular structure and function analysed, only the IMT shows association with the smoking status, after adjusting for confounders.

View Article: PubMed Central - HTML - PubMed

Affiliation: La Alamedilla Health Centre, Castilla y León Health Service-SACYL, redIAPP, IBSAL, Salamanca, Spain. donrecio@gmail.com.

ABSTRACT

Background: The present study analyses the relation between smoking status and the parameters used to assess vascular structure and function.

Methods: This cross-sectional, multi-centre study involved a random sample of 1553 participants from the EVIDENT study.

Measurements: The smoking status, peripheral augmentation index and ankle-brachial index were measured in all participants. In a small subset of the main population (265 participants), the carotid intima-media thickness and pulse wave velocity were also measured.

Results: After controlling for the effect of age, sex and other risk factors, present smokers have higher values of carotid intima-media thickness (p = 0.011). Along the same lines, current smokers have higher values of pulse wave velocity and lower mean values of ankle-brachial index but without statistical significance in both cases.

Conclusions: Among the parameters of vascular structure and function analysed, only the IMT shows association with the smoking status, after adjusting for confounders.

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Related in: MedlinePlus

Relationship between the smoking status, vascular structure and function parameters adjusted by age, sex, systolic blood pressure, heart rate, body mass index, HDL cholesterol, diabetes and the presence of antihypertensive, antidiabetic and lipid-lowering drugs. Figure represents the adjusted means and 95% CI. Statistical significance: IMT p = 0.011*, PWV p = 0.872, PAIx75 p = 0.150, ABI p = 0.464.
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Figure 2: Relationship between the smoking status, vascular structure and function parameters adjusted by age, sex, systolic blood pressure, heart rate, body mass index, HDL cholesterol, diabetes and the presence of antihypertensive, antidiabetic and lipid-lowering drugs. Figure represents the adjusted means and 95% CI. Statistical significance: IMT p = 0.011*, PWV p = 0.872, PAIx75 p = 0.150, ABI p = 0.464.

Mentions: After controlling for the effects of age, sex, systolic blood pressure, heart rate, body mass index, HDL-cholesterol, diabetes and the presence of antihypertensive, antidiabetic and lipid-lowering drugs, the multivariate analysis shows that present smokers have higher IMT values (p = 0.011). PWV behaves likewise, although it does not reach the level of statistical significance. ABI has no modifications, and PAIx75 has higher values in current smokers than in former smokers (Figure 2). More details of the multivariate analysis are shown in Table 2 of the Additional file 2: (Table S2).


Association between smoking status and the parameters of vascular structure and function in adults: results from the EVIDENT study.

Recio-Rodriguez JI, Gomez-Marcos MA, Patino Alonso MC, Martin-Cantera C, Ibañez-Jalon E, Melguizo-Bejar A, Garcia-Ortiz L, EVIDENT Gro - BMC Cardiovasc Disord (2013)

Relationship between the smoking status, vascular structure and function parameters adjusted by age, sex, systolic blood pressure, heart rate, body mass index, HDL cholesterol, diabetes and the presence of antihypertensive, antidiabetic and lipid-lowering drugs. Figure represents the adjusted means and 95% CI. Statistical significance: IMT p = 0.011*, PWV p = 0.872, PAIx75 p = 0.150, ABI p = 0.464.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4219389&req=5

Figure 2: Relationship between the smoking status, vascular structure and function parameters adjusted by age, sex, systolic blood pressure, heart rate, body mass index, HDL cholesterol, diabetes and the presence of antihypertensive, antidiabetic and lipid-lowering drugs. Figure represents the adjusted means and 95% CI. Statistical significance: IMT p = 0.011*, PWV p = 0.872, PAIx75 p = 0.150, ABI p = 0.464.
Mentions: After controlling for the effects of age, sex, systolic blood pressure, heart rate, body mass index, HDL-cholesterol, diabetes and the presence of antihypertensive, antidiabetic and lipid-lowering drugs, the multivariate analysis shows that present smokers have higher IMT values (p = 0.011). PWV behaves likewise, although it does not reach the level of statistical significance. ABI has no modifications, and PAIx75 has higher values in current smokers than in former smokers (Figure 2). More details of the multivariate analysis are shown in Table 2 of the Additional file 2: (Table S2).

Bottom Line: After controlling for the effect of age, sex and other risk factors, present smokers have higher values of carotid intima-media thickness (p = 0.011).Along the same lines, current smokers have higher values of pulse wave velocity and lower mean values of ankle-brachial index but without statistical significance in both cases.Among the parameters of vascular structure and function analysed, only the IMT shows association with the smoking status, after adjusting for confounders.

View Article: PubMed Central - HTML - PubMed

Affiliation: La Alamedilla Health Centre, Castilla y León Health Service-SACYL, redIAPP, IBSAL, Salamanca, Spain. donrecio@gmail.com.

ABSTRACT

Background: The present study analyses the relation between smoking status and the parameters used to assess vascular structure and function.

Methods: This cross-sectional, multi-centre study involved a random sample of 1553 participants from the EVIDENT study.

Measurements: The smoking status, peripheral augmentation index and ankle-brachial index were measured in all participants. In a small subset of the main population (265 participants), the carotid intima-media thickness and pulse wave velocity were also measured.

Results: After controlling for the effect of age, sex and other risk factors, present smokers have higher values of carotid intima-media thickness (p = 0.011). Along the same lines, current smokers have higher values of pulse wave velocity and lower mean values of ankle-brachial index but without statistical significance in both cases.

Conclusions: Among the parameters of vascular structure and function analysed, only the IMT shows association with the smoking status, after adjusting for confounders.

Show MeSH
Related in: MedlinePlus