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An unusual ocular emergency in severe dengue.

Nagaraj KB, Jayadev C, Yajmaan S, Prakash S - Middle East Afr J Ophthalmol (2014 Oct-Dec)

Bottom Line: Severe dengue is defined as that associated with severe bleeding, severe organ dysfunction, or severe plasma leakage.Ophthalmic manifestations can involve both the anterior and posterior segment.We report an ocular emergency of proptosis and globe rupture in a patient with severe dengue.

View Article: PubMed Central - PubMed

Affiliation: Department of Vitreoretina, Minto Ophthalmic Hospital, Bangalore Medical College and Research Institute, Bangalore, Karnataka, India.

ABSTRACT
Dengue, one of the most common mosquito-borne flavivirus diseases affecting humans, is spread by the Aedes aegypti mosquito. Most people infected with dengue virus are asymptomatic or only have mild symptoms such as an uncomplicated fever; few have more severe features, while in a small proportion it is life-threatening. Severe dengue is defined as that associated with severe bleeding, severe organ dysfunction, or severe plasma leakage. Ophthalmic manifestations can involve both the anterior and posterior segment. We report an ocular emergency of proptosis and globe rupture in a patient with severe dengue.

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Related in: MedlinePlus

Platelet count
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Figure 1: Platelet count

Mentions: A 20-year-old male presented with complains of pain and swelling in the left eye since two days, which occurred after rubbing his eye vigorously due to an itching sensation. He had been admitted to the medicine department three days before with a history of fever, abdominal pain, and vomiting of five days duration with one episode of gum bleeding. On investigation, the peripheral smear was negative for malarial parasite and all other routine investigations were within normal limits, except for thrombocytopenia with counts of 57,000/microliter (normal 150,000-450,000/microliter). His counts steadily dropped and were 9,000/microliter two days after admission. A diagnosis of dengue fever was made after IgG levels were noted to be >200 RU/ml (normal range 16-22 RU/ml), IgM 0.3 (0.8-1.1), and NSI antigen 0.4 (0.3-1). He was started on supportive therapy and platelet transfusions (15 units of 50 ml over the course of his admission), following which there was an improvement in platelet count [Figure 1].


An unusual ocular emergency in severe dengue.

Nagaraj KB, Jayadev C, Yajmaan S, Prakash S - Middle East Afr J Ophthalmol (2014 Oct-Dec)

Platelet count
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4219229&req=5

Figure 1: Platelet count
Mentions: A 20-year-old male presented with complains of pain and swelling in the left eye since two days, which occurred after rubbing his eye vigorously due to an itching sensation. He had been admitted to the medicine department three days before with a history of fever, abdominal pain, and vomiting of five days duration with one episode of gum bleeding. On investigation, the peripheral smear was negative for malarial parasite and all other routine investigations were within normal limits, except for thrombocytopenia with counts of 57,000/microliter (normal 150,000-450,000/microliter). His counts steadily dropped and were 9,000/microliter two days after admission. A diagnosis of dengue fever was made after IgG levels were noted to be >200 RU/ml (normal range 16-22 RU/ml), IgM 0.3 (0.8-1.1), and NSI antigen 0.4 (0.3-1). He was started on supportive therapy and platelet transfusions (15 units of 50 ml over the course of his admission), following which there was an improvement in platelet count [Figure 1].

Bottom Line: Severe dengue is defined as that associated with severe bleeding, severe organ dysfunction, or severe plasma leakage.Ophthalmic manifestations can involve both the anterior and posterior segment.We report an ocular emergency of proptosis and globe rupture in a patient with severe dengue.

View Article: PubMed Central - PubMed

Affiliation: Department of Vitreoretina, Minto Ophthalmic Hospital, Bangalore Medical College and Research Institute, Bangalore, Karnataka, India.

ABSTRACT
Dengue, one of the most common mosquito-borne flavivirus diseases affecting humans, is spread by the Aedes aegypti mosquito. Most people infected with dengue virus are asymptomatic or only have mild symptoms such as an uncomplicated fever; few have more severe features, while in a small proportion it is life-threatening. Severe dengue is defined as that associated with severe bleeding, severe organ dysfunction, or severe plasma leakage. Ophthalmic manifestations can involve both the anterior and posterior segment. We report an ocular emergency of proptosis and globe rupture in a patient with severe dengue.

Show MeSH
Related in: MedlinePlus