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Dynamics of macronutrient self-medication and illness-induced anorexia in virally infected insects.

Povey S, Cotter SC, Simpson SJ, Wilson K - J Anim Ecol (2013)

Bottom Line: This 'self-medication' is typically considered to involve the consumption of toxins, minerals or secondary compounds.Infected individuals might also reduce food intake when infected (i.e. illness-induced anorexia).This was mostly due to a sharp decline in carbohydrate intake, rather than an increased intake of protein, reducing overall food intake, consistent with an illness-induced anorexic response.

View Article: PubMed Central - PubMed

Affiliation: Lancaster Environment Centre, Lancaster University, Lancaster, LA1 4YQ, UK.

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Related in: MedlinePlus

Survival curves for larvae restricted to one of five diets varying in their protein-to-carbohydrate ratios (P: C) and inoculated with either an LD50 dose of nucleopolyhedrovirus (NPV) or with water (controls). Data are taken from Experiment 1, no-choice treatment.
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fig01: Survival curves for larvae restricted to one of five diets varying in their protein-to-carbohydrate ratios (P: C) and inoculated with either an LD50 dose of nucleopolyhedrovirus (NPV) or with water (controls). Data are taken from Experiment 1, no-choice treatment.

Mentions: Larvae started to die from virus 4 days post-inoculation, and all larvae had either died or pupated by 10 days. Larval risk of death was affected by both viral inoculation (AFT model, treatment: = 82·30, P < 0·0001) and the relative protein content of the diet (diet, = 33·35, P < 0·0001). No other interactions were statistically significant. As expected, larvae inoculated with NPV had substantially lower survival than those in the control group (mean survival: control = 98%, NPV-challenged = 54%; estimate ± SE = −0·40 ± 0·09; Fig. 1). Whereas survival in the non-challenged insects was uniformly high (>95%) across diet treatments, in the virus-challenged larvae, survival increased with the ratio of protein to carbohydrates (estimate ± SE = 0·60 ± 0·01; Fig. 1), such that on the most protein-rich diet (35: 7), 79% of the virally challenged larvae survived, compared to just 33% on the most protein-poor diet (7: 35).


Dynamics of macronutrient self-medication and illness-induced anorexia in virally infected insects.

Povey S, Cotter SC, Simpson SJ, Wilson K - J Anim Ecol (2013)

Survival curves for larvae restricted to one of five diets varying in their protein-to-carbohydrate ratios (P: C) and inoculated with either an LD50 dose of nucleopolyhedrovirus (NPV) or with water (controls). Data are taken from Experiment 1, no-choice treatment.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4217384&req=5

fig01: Survival curves for larvae restricted to one of five diets varying in their protein-to-carbohydrate ratios (P: C) and inoculated with either an LD50 dose of nucleopolyhedrovirus (NPV) or with water (controls). Data are taken from Experiment 1, no-choice treatment.
Mentions: Larvae started to die from virus 4 days post-inoculation, and all larvae had either died or pupated by 10 days. Larval risk of death was affected by both viral inoculation (AFT model, treatment: = 82·30, P < 0·0001) and the relative protein content of the diet (diet, = 33·35, P < 0·0001). No other interactions were statistically significant. As expected, larvae inoculated with NPV had substantially lower survival than those in the control group (mean survival: control = 98%, NPV-challenged = 54%; estimate ± SE = −0·40 ± 0·09; Fig. 1). Whereas survival in the non-challenged insects was uniformly high (>95%) across diet treatments, in the virus-challenged larvae, survival increased with the ratio of protein to carbohydrates (estimate ± SE = 0·60 ± 0·01; Fig. 1), such that on the most protein-rich diet (35: 7), 79% of the virally challenged larvae survived, compared to just 33% on the most protein-poor diet (7: 35).

Bottom Line: This 'self-medication' is typically considered to involve the consumption of toxins, minerals or secondary compounds.Infected individuals might also reduce food intake when infected (i.e. illness-induced anorexia).This was mostly due to a sharp decline in carbohydrate intake, rather than an increased intake of protein, reducing overall food intake, consistent with an illness-induced anorexic response.

View Article: PubMed Central - PubMed

Affiliation: Lancaster Environment Centre, Lancaster University, Lancaster, LA1 4YQ, UK.

Show MeSH
Related in: MedlinePlus