Limits...
Value of perfusion weighted magnetic resonance imaging in the diagnosis of supratentorial anaplastic astrocytoma.

Lee KM, Kim EJ, Jahng GH, Park BJ - J Korean Neurosurg Soc (2014)

Bottom Line: Brain magnetic resonance imaging showed a nonenhanced brain tumor with mild peritumoral edema on the right medial frontal lobe and right genu of corpus callosum, suggesting a low-grade glioma.However, PWI showed increased relative cerebral blood volume, relative cerebral blood flow, and permeability of nonenhanced brain tumor compared with contralateral normal brain parenchyma, suggesting a high-grade glioma.This case demonstrates the importance of PWI for preoperative evaluation of nonenhanced brain tumors.

View Article: PubMed Central - PubMed

Affiliation: Department of Radiology, Seoul National University Bundang Hospital, Seongnam, Korea.

ABSTRACT
We report perfusion weighted imaging (PWI) findings of nonenhanced anaplastic astrocytoma in a 30-year-old woman. Brain magnetic resonance imaging showed a nonenhanced brain tumor with mild peritumoral edema on the right medial frontal lobe and right genu of corpus callosum, suggesting a low-grade glioma. However, PWI showed increased relative cerebral blood volume, relative cerebral blood flow, and permeability of nonenhanced brain tumor compared with contralateral normal brain parenchyma, suggesting a high-grade glioma. After surgery, final histopathological analysis revealed World Health Organization grade III anaplastic astrocytoma. This case demonstrates the importance of PWI for preoperative evaluation of nonenhanced brain tumors.

No MeSH data available.


Related in: MedlinePlus

Perfusion color maps derived from dynamic susceptibility contrast-enhanced perfusion weighted imaging show that the visual increase in the relative cerebral blood volume of 3.6 (A) and relative cerebral blood flow of 2.0 (B).
© Copyright Policy - open-access
Related In: Results  -  Collection

License
getmorefigures.php?uid=PMC4217066&req=5

Figure 2: Perfusion color maps derived from dynamic susceptibility contrast-enhanced perfusion weighted imaging show that the visual increase in the relative cerebral blood volume of 3.6 (A) and relative cerebral blood flow of 2.0 (B).

Mentions: Results of brain MRI confirmed the presence of a tumor, which had low signal intensity on T1WI, but high signal intensity on T2WI. Gadolinium-enhanced T1WI showed a tumor without enhancement (Fig. 1). There was a local mass effect on the adjacent right lateral ventricle and a small amount of associated edema (Fig. 1). Correspondingly high rCBV, rCBF, AUC and increas-ed permeability color values were detected (Fig. 2, 3). Maximal rCBV and rCBF ratios were also high, at 3.6 and 3.1, respectively. There was a mismatch between the perfusion maps, which suggested high-grade glioma, and enhanced T1WI, which suggested low-grade glioma.


Value of perfusion weighted magnetic resonance imaging in the diagnosis of supratentorial anaplastic astrocytoma.

Lee KM, Kim EJ, Jahng GH, Park BJ - J Korean Neurosurg Soc (2014)

Perfusion color maps derived from dynamic susceptibility contrast-enhanced perfusion weighted imaging show that the visual increase in the relative cerebral blood volume of 3.6 (A) and relative cerebral blood flow of 2.0 (B).
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4217066&req=5

Figure 2: Perfusion color maps derived from dynamic susceptibility contrast-enhanced perfusion weighted imaging show that the visual increase in the relative cerebral blood volume of 3.6 (A) and relative cerebral blood flow of 2.0 (B).
Mentions: Results of brain MRI confirmed the presence of a tumor, which had low signal intensity on T1WI, but high signal intensity on T2WI. Gadolinium-enhanced T1WI showed a tumor without enhancement (Fig. 1). There was a local mass effect on the adjacent right lateral ventricle and a small amount of associated edema (Fig. 1). Correspondingly high rCBV, rCBF, AUC and increas-ed permeability color values were detected (Fig. 2, 3). Maximal rCBV and rCBF ratios were also high, at 3.6 and 3.1, respectively. There was a mismatch between the perfusion maps, which suggested high-grade glioma, and enhanced T1WI, which suggested low-grade glioma.

Bottom Line: Brain magnetic resonance imaging showed a nonenhanced brain tumor with mild peritumoral edema on the right medial frontal lobe and right genu of corpus callosum, suggesting a low-grade glioma.However, PWI showed increased relative cerebral blood volume, relative cerebral blood flow, and permeability of nonenhanced brain tumor compared with contralateral normal brain parenchyma, suggesting a high-grade glioma.This case demonstrates the importance of PWI for preoperative evaluation of nonenhanced brain tumors.

View Article: PubMed Central - PubMed

Affiliation: Department of Radiology, Seoul National University Bundang Hospital, Seongnam, Korea.

ABSTRACT
We report perfusion weighted imaging (PWI) findings of nonenhanced anaplastic astrocytoma in a 30-year-old woman. Brain magnetic resonance imaging showed a nonenhanced brain tumor with mild peritumoral edema on the right medial frontal lobe and right genu of corpus callosum, suggesting a low-grade glioma. However, PWI showed increased relative cerebral blood volume, relative cerebral blood flow, and permeability of nonenhanced brain tumor compared with contralateral normal brain parenchyma, suggesting a high-grade glioma. After surgery, final histopathological analysis revealed World Health Organization grade III anaplastic astrocytoma. This case demonstrates the importance of PWI for preoperative evaluation of nonenhanced brain tumors.

No MeSH data available.


Related in: MedlinePlus