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Clear-cornea cataract surgery: pupil size and shape changes, along with anterior chamber volume and depth changes. A Scheimpflug imaging study.

Kanellopoulos AJ, Asimellis G - Clin Ophthalmol (2014)

Bottom Line: Pupil size analysis showed that the horizontal pupil diameter was reduced by -0.27±0.22 mm (-9.7%; P=0.001) and the vertical pupil diameter was reduced by -0.32±0.24 mm (-11%; P<0.001).Pupil eccentricity was reduced by -39.56%; P<0.001.These changes appear to be more significant with increasing patient age.

View Article: PubMed Central - PubMed

Affiliation: Laservision.gr Eye Institute, Athens, Greece ; New York University School of Medicine, New York, NY, USA.

ABSTRACT

Purpose: To investigate, by high-precision digital analysis of data provided by Scheimpflug imaging, changes in pupil size and shape and anterior chamber (AC) parameters following cataract surgery.

Patients and methods: The study group (86 eyes, patient age 70.58±10.33 years) was subjected to cataract removal surgery with in-the-bag intraocular lens implantation (pseudophakic). A control group of 75 healthy eyes (patient age 51.14±16.27 years) was employed for comparison. Scheimpflug imaging (preoperatively and 3 months postoperatively) was employed to investigate central corneal thickness, AC depth, and AC volume. In addition, by digitally analyzing the black-and-white dotted line pupil edge marking in the Scheimpflug "large maps," the horizontal and vertical pupil diameters were individually measured and the pupil eccentricity was calculated. The correlations between AC depth and pupil shape parameters versus patient age, as well as the postoperative AC and pupil size and shape changes, were investigated.

Results: Compared to preoperative measurements, AC depth and AC volume of the pseudophakic eyes increased by 0.99±0.46 mm (39%; P<0.001) and 43.57±24.59 mm(3) (36%; P<0.001), respectively. Pupil size analysis showed that the horizontal pupil diameter was reduced by -0.27±0.22 mm (-9.7%; P=0.001) and the vertical pupil diameter was reduced by -0.32±0.24 mm (-11%; P<0.001). Pupil eccentricity was reduced by -39.56%; P<0.001.

Conclusion: Cataract extraction surgery appears to affect pupil size and shape, possibly in correlation to AC depth increase. This novel investigation based on digital analysis of Scheimpflug imaging data suggests that the cataract postoperative photopic pupil is reduced and more circular. These changes appear to be more significant with increasing patient age.

No MeSH data available.


Related in: MedlinePlus

Fitted line plots of pupil diameter change with cataract surgery, as a function of age.Notes: (A) A fitted line plot of horizontal pupil diameter relative change, expressed as a fraction of the preoperative value, as a result of cataract surgery (n=86 eyes) versus patient age. (B) A fitted line plot of vertical pupil diameter relative change, expressed as a fraction of the preoperative value, as a result of cataract surgery (n=86 eyes) versus patient age.Abbreviations: CI, confidence interval; PI, prediction interval; Pup, pupil; R-sq, coefficient of determination; R-sq (adj), adjusted coefficient of determination; S, sum of residuals; X∅, horizontal pupil diameter; Y∅, vertical pupil diameter.
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f3-opth-8-2141: Fitted line plots of pupil diameter change with cataract surgery, as a function of age.Notes: (A) A fitted line plot of horizontal pupil diameter relative change, expressed as a fraction of the preoperative value, as a result of cataract surgery (n=86 eyes) versus patient age. (B) A fitted line plot of vertical pupil diameter relative change, expressed as a fraction of the preoperative value, as a result of cataract surgery (n=86 eyes) versus patient age.Abbreviations: CI, confidence interval; PI, prediction interval; Pup, pupil; R-sq, coefficient of determination; R-sq (adj), adjusted coefficient of determination; S, sum of residuals; X∅, horizontal pupil diameter; Y∅, vertical pupil diameter.

Mentions: Pupil diameter also showed a statistically significant change towards a smaller postoperative average diameter. Specifically, pupil diameter, as reported by the Scheimpflug system, was 2.83±0.53 (1.83–4.13) mm preoperatively and 2.66±0.50 (1.71–4.04) mm postoperatively (P=0.0368). The horizontal pupil diameter (X∅) was 2.77±0.47 (1.92–4.09) mm preoperatively and 2.50±0.41 (1.73–3.76) mm postoperatively (P=0.0001), and the vertical pupil diameter (Y∅) was 2.86±0.49 (1.95–4.20) mm preoperatively and 2.54±0.42 (1.73–3.90) mm postoperatively (P<0.001). Figure 3 illustrates the pupil diameter change (horizontal in Figure 3A and vertical in Figure 3B), expressed as a percentage of the preoperative value, as a result of cataract surgery in the form of a fitted line plot versus patient age.


Clear-cornea cataract surgery: pupil size and shape changes, along with anterior chamber volume and depth changes. A Scheimpflug imaging study.

Kanellopoulos AJ, Asimellis G - Clin Ophthalmol (2014)

Fitted line plots of pupil diameter change with cataract surgery, as a function of age.Notes: (A) A fitted line plot of horizontal pupil diameter relative change, expressed as a fraction of the preoperative value, as a result of cataract surgery (n=86 eyes) versus patient age. (B) A fitted line plot of vertical pupil diameter relative change, expressed as a fraction of the preoperative value, as a result of cataract surgery (n=86 eyes) versus patient age.Abbreviations: CI, confidence interval; PI, prediction interval; Pup, pupil; R-sq, coefficient of determination; R-sq (adj), adjusted coefficient of determination; S, sum of residuals; X∅, horizontal pupil diameter; Y∅, vertical pupil diameter.
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4216028&req=5

f3-opth-8-2141: Fitted line plots of pupil diameter change with cataract surgery, as a function of age.Notes: (A) A fitted line plot of horizontal pupil diameter relative change, expressed as a fraction of the preoperative value, as a result of cataract surgery (n=86 eyes) versus patient age. (B) A fitted line plot of vertical pupil diameter relative change, expressed as a fraction of the preoperative value, as a result of cataract surgery (n=86 eyes) versus patient age.Abbreviations: CI, confidence interval; PI, prediction interval; Pup, pupil; R-sq, coefficient of determination; R-sq (adj), adjusted coefficient of determination; S, sum of residuals; X∅, horizontal pupil diameter; Y∅, vertical pupil diameter.
Mentions: Pupil diameter also showed a statistically significant change towards a smaller postoperative average diameter. Specifically, pupil diameter, as reported by the Scheimpflug system, was 2.83±0.53 (1.83–4.13) mm preoperatively and 2.66±0.50 (1.71–4.04) mm postoperatively (P=0.0368). The horizontal pupil diameter (X∅) was 2.77±0.47 (1.92–4.09) mm preoperatively and 2.50±0.41 (1.73–3.76) mm postoperatively (P=0.0001), and the vertical pupil diameter (Y∅) was 2.86±0.49 (1.95–4.20) mm preoperatively and 2.54±0.42 (1.73–3.90) mm postoperatively (P<0.001). Figure 3 illustrates the pupil diameter change (horizontal in Figure 3A and vertical in Figure 3B), expressed as a percentage of the preoperative value, as a result of cataract surgery in the form of a fitted line plot versus patient age.

Bottom Line: Pupil size analysis showed that the horizontal pupil diameter was reduced by -0.27±0.22 mm (-9.7%; P=0.001) and the vertical pupil diameter was reduced by -0.32±0.24 mm (-11%; P<0.001).Pupil eccentricity was reduced by -39.56%; P<0.001.These changes appear to be more significant with increasing patient age.

View Article: PubMed Central - PubMed

Affiliation: Laservision.gr Eye Institute, Athens, Greece ; New York University School of Medicine, New York, NY, USA.

ABSTRACT

Purpose: To investigate, by high-precision digital analysis of data provided by Scheimpflug imaging, changes in pupil size and shape and anterior chamber (AC) parameters following cataract surgery.

Patients and methods: The study group (86 eyes, patient age 70.58±10.33 years) was subjected to cataract removal surgery with in-the-bag intraocular lens implantation (pseudophakic). A control group of 75 healthy eyes (patient age 51.14±16.27 years) was employed for comparison. Scheimpflug imaging (preoperatively and 3 months postoperatively) was employed to investigate central corneal thickness, AC depth, and AC volume. In addition, by digitally analyzing the black-and-white dotted line pupil edge marking in the Scheimpflug "large maps," the horizontal and vertical pupil diameters were individually measured and the pupil eccentricity was calculated. The correlations between AC depth and pupil shape parameters versus patient age, as well as the postoperative AC and pupil size and shape changes, were investigated.

Results: Compared to preoperative measurements, AC depth and AC volume of the pseudophakic eyes increased by 0.99±0.46 mm (39%; P<0.001) and 43.57±24.59 mm(3) (36%; P<0.001), respectively. Pupil size analysis showed that the horizontal pupil diameter was reduced by -0.27±0.22 mm (-9.7%; P=0.001) and the vertical pupil diameter was reduced by -0.32±0.24 mm (-11%; P<0.001). Pupil eccentricity was reduced by -39.56%; P<0.001.

Conclusion: Cataract extraction surgery appears to affect pupil size and shape, possibly in correlation to AC depth increase. This novel investigation based on digital analysis of Scheimpflug imaging data suggests that the cataract postoperative photopic pupil is reduced and more circular. These changes appear to be more significant with increasing patient age.

No MeSH data available.


Related in: MedlinePlus