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Prevalence and control of hypertension and albuminuria in South Korea: focus on obesity and abdominal obesity in the Korean National Health and Nutrition Examination Survey, 2011-2012.

Yoon SJ, Kim DH, Nam GE, Yoon YJ, Han KD, Jung DW, Park SW, Kim YE, Lee SH, Lee SS, Kim YH - PLoS ONE (2014)

Bottom Line: Subjects were divided into four groups: non-obese/normal waist circumference, non-obese/high waist circumference, obese/normal waist circumference, and obese/high waist circumference.Systolic blood pressure and diastolic blood pressure were positively associated with albumin-creatinine ratio in all groups (all p values <0.005).Non-obese and normal waist circumference subjects have an increased prevalence and decreased control of hypertension in microalbuminuria and macroalbuminuria levels.

View Article: PubMed Central - PubMed

Affiliation: Department of Family Medicine, Korea University College of Medicine, Seoul, South Korea.

ABSTRACT

Background: Albuminuria is associated with cardiovascular disease, and the relationship between albuminuria and hypertension is well established in many studies. So the control of hypertension is critical for decreasing cardiovascular events and albuminuria. Obesity and abdominal obesity are also associated with hypertension and albuminuria. Therefore, we analyzed the relationship between albuminuria and the prevalence and control of hypertension in the general Korean population according to obesity status.

Methods: We analyzed data from the 2011-2012 Korea National Health and Nutrition Examination Survey, and 9,519 subjects were included. Subjects were divided into four groups: non-obese/normal waist circumference, non-obese/high waist circumference, obese/normal waist circumference, and obese/high waist circumference.

Results: Systolic blood pressure and diastolic blood pressure were positively associated with albumin-creatinine ratio in all groups (all p values <0.005). Non-obese/normal waist circumference group were more likely to have hypertension (odds ratios [95% confidential intervals (CIs)] were 3.20 [2.21-4.63] in microalbuminuria level and 3.09 [1.05-9.14] in macroalbuminuria level), and less likely to have controlled hypertension (odds ratios <1 for both albuminuria levels) after adjusting for all covariates. Obese/normal waist circumference group were also more likely to have hypertension (odds ratio [95% CI] were 3.10 [1.56-6.15] in microalbuminuria level and 21.75 [3.66-129.04] in macroalbuminuria level), and less likely to have controlled hypertension in macroalbuminuria level (odds ratio [95% CI], 0.04 [0.01-0.15]).

Conclusions: Non-obese and normal waist circumference subjects have an increased prevalence and decreased control of hypertension in microalbuminuria and macroalbuminuria levels. Screening for albuminuria may provide helpful information about hypertension and blood pressure control, particularly in the non-obese and normal waist circumference subjects.

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Related in: MedlinePlus

Prevalence of HTN in subjects with and without obesity and abdominal obesity by tertile of ACR.All p values for trends were <0.001. All p values were <0.001 between two groups; ACR <30 vs. 30≤ ACR <300, and ACR <30 vs. ACR ≥300 at all groups. HTN, hypertension; ACR, albumin–creatinine ratio; WC, waist circumference.
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pone-0111179-g001: Prevalence of HTN in subjects with and without obesity and abdominal obesity by tertile of ACR.All p values for trends were <0.001. All p values were <0.001 between two groups; ACR <30 vs. 30≤ ACR <300, and ACR <30 vs. ACR ≥300 at all groups. HTN, hypertension; ACR, albumin–creatinine ratio; WC, waist circumference.

Mentions: We compared the prevalence of HTN with the ACR tertiles in subjects with and without obesity and abdominal obesity (Figure 1). In all groups, the prevalence of HTN increased as ACR increased (all p values for trends were <0.001). There were differences in the prevalence of HTN between two groups among the four obese and non-obese groups when ACR was analyzed: ACR <30 vs. 30≤ ACR <300, and ACR <30 vs. ACR ≥300. In Figure 2, we compared the control rate of HTN according to the ACR tertile. In the non-obese/high WC group only, the rate of HTN control decreased significantly as the ACR increased (p value for trend <0.001). The control of HTN was significantly different between two groups: ACR <30 vs. 30≤ ACR <300, and ACR <30 vs. ACR ≥300 in non-obese/normal WC group (both p values <0.05). The p values and p values for trends were not statistically significant in the other three groups.


Prevalence and control of hypertension and albuminuria in South Korea: focus on obesity and abdominal obesity in the Korean National Health and Nutrition Examination Survey, 2011-2012.

Yoon SJ, Kim DH, Nam GE, Yoon YJ, Han KD, Jung DW, Park SW, Kim YE, Lee SH, Lee SS, Kim YH - PLoS ONE (2014)

Prevalence of HTN in subjects with and without obesity and abdominal obesity by tertile of ACR.All p values for trends were <0.001. All p values were <0.001 between two groups; ACR <30 vs. 30≤ ACR <300, and ACR <30 vs. ACR ≥300 at all groups. HTN, hypertension; ACR, albumin–creatinine ratio; WC, waist circumference.
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4215993&req=5

pone-0111179-g001: Prevalence of HTN in subjects with and without obesity and abdominal obesity by tertile of ACR.All p values for trends were <0.001. All p values were <0.001 between two groups; ACR <30 vs. 30≤ ACR <300, and ACR <30 vs. ACR ≥300 at all groups. HTN, hypertension; ACR, albumin–creatinine ratio; WC, waist circumference.
Mentions: We compared the prevalence of HTN with the ACR tertiles in subjects with and without obesity and abdominal obesity (Figure 1). In all groups, the prevalence of HTN increased as ACR increased (all p values for trends were <0.001). There were differences in the prevalence of HTN between two groups among the four obese and non-obese groups when ACR was analyzed: ACR <30 vs. 30≤ ACR <300, and ACR <30 vs. ACR ≥300. In Figure 2, we compared the control rate of HTN according to the ACR tertile. In the non-obese/high WC group only, the rate of HTN control decreased significantly as the ACR increased (p value for trend <0.001). The control of HTN was significantly different between two groups: ACR <30 vs. 30≤ ACR <300, and ACR <30 vs. ACR ≥300 in non-obese/normal WC group (both p values <0.05). The p values and p values for trends were not statistically significant in the other three groups.

Bottom Line: Subjects were divided into four groups: non-obese/normal waist circumference, non-obese/high waist circumference, obese/normal waist circumference, and obese/high waist circumference.Systolic blood pressure and diastolic blood pressure were positively associated with albumin-creatinine ratio in all groups (all p values <0.005).Non-obese and normal waist circumference subjects have an increased prevalence and decreased control of hypertension in microalbuminuria and macroalbuminuria levels.

View Article: PubMed Central - PubMed

Affiliation: Department of Family Medicine, Korea University College of Medicine, Seoul, South Korea.

ABSTRACT

Background: Albuminuria is associated with cardiovascular disease, and the relationship between albuminuria and hypertension is well established in many studies. So the control of hypertension is critical for decreasing cardiovascular events and albuminuria. Obesity and abdominal obesity are also associated with hypertension and albuminuria. Therefore, we analyzed the relationship between albuminuria and the prevalence and control of hypertension in the general Korean population according to obesity status.

Methods: We analyzed data from the 2011-2012 Korea National Health and Nutrition Examination Survey, and 9,519 subjects were included. Subjects were divided into four groups: non-obese/normal waist circumference, non-obese/high waist circumference, obese/normal waist circumference, and obese/high waist circumference.

Results: Systolic blood pressure and diastolic blood pressure were positively associated with albumin-creatinine ratio in all groups (all p values <0.005). Non-obese/normal waist circumference group were more likely to have hypertension (odds ratios [95% confidential intervals (CIs)] were 3.20 [2.21-4.63] in microalbuminuria level and 3.09 [1.05-9.14] in macroalbuminuria level), and less likely to have controlled hypertension (odds ratios <1 for both albuminuria levels) after adjusting for all covariates. Obese/normal waist circumference group were also more likely to have hypertension (odds ratio [95% CI] were 3.10 [1.56-6.15] in microalbuminuria level and 21.75 [3.66-129.04] in macroalbuminuria level), and less likely to have controlled hypertension in macroalbuminuria level (odds ratio [95% CI], 0.04 [0.01-0.15]).

Conclusions: Non-obese and normal waist circumference subjects have an increased prevalence and decreased control of hypertension in microalbuminuria and macroalbuminuria levels. Screening for albuminuria may provide helpful information about hypertension and blood pressure control, particularly in the non-obese and normal waist circumference subjects.

Show MeSH
Related in: MedlinePlus