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Advances in epilepsy surgery.

Nowell M, Miserocchi A, McEvoy AW, Duncan JS - J. Neurol. Neurosurg. Psychiatr. (2014)

Bottom Line: This review summarises exciting recent and forthcoming advances that will impact on the surgical management of epilepsy in the near future.This does not cover the current accepted diagnostic methodologies or surgical treatments that are routinely practiced today.The content of this review was derived from a PubMed literature search, using the key words 'Epilepsy Surgery', 'Neuromodulation', 'Neuroablation', 'Advances', between 2010 and November 2013.

View Article: PubMed Central - PubMed

Affiliation: Department of Clinical and Experimental Epilepsy, UCL Institute of Neurology, London, UK MRI Unit, Epilepsy Society, Chalfont St Peter, UK Department of Neurosurgery, National Hospital for Neurology and Neurosurgery, London, UK.

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Related in: MedlinePlus

Volume rendering of cortex (grey) displayed in AMIRA with the following associated modalities: focal cortical dysplasia (red), fluorodeoxy glucose positron emission tomography (FDG-PET). hypometabolism (purple), hand motor fMRI (green), corticospinal tractography (blue), veins (cyan).
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JNNP2013307069F1: Volume rendering of cortex (grey) displayed in AMIRA with the following associated modalities: focal cortical dysplasia (red), fluorodeoxy glucose positron emission tomography (FDG-PET). hypometabolism (purple), hand motor fMRI (green), corticospinal tractography (blue), veins (cyan).

Mentions: 3D multimodality imaging is the simultaneous display of different structural and functional datasets, tailored to individual patients. The feasibility of this additional tool in a busy epilepsy surgery practice has been demonstrated,7 and a prospective study is currently underway to validate the usefulness of this in presurgical evaluation and surgical management. Ultimately, improvements in the surgical outcomes in this patient group will depend on better imaging, including visualisation of electrical abnormalities in 3D, reliable imaging integration and robust planning and implementation of intracranial EEG (figure 1).


Advances in epilepsy surgery.

Nowell M, Miserocchi A, McEvoy AW, Duncan JS - J. Neurol. Neurosurg. Psychiatr. (2014)

Volume rendering of cortex (grey) displayed in AMIRA with the following associated modalities: focal cortical dysplasia (red), fluorodeoxy glucose positron emission tomography (FDG-PET). hypometabolism (purple), hand motor fMRI (green), corticospinal tractography (blue), veins (cyan).
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4215277&req=5

JNNP2013307069F1: Volume rendering of cortex (grey) displayed in AMIRA with the following associated modalities: focal cortical dysplasia (red), fluorodeoxy glucose positron emission tomography (FDG-PET). hypometabolism (purple), hand motor fMRI (green), corticospinal tractography (blue), veins (cyan).
Mentions: 3D multimodality imaging is the simultaneous display of different structural and functional datasets, tailored to individual patients. The feasibility of this additional tool in a busy epilepsy surgery practice has been demonstrated,7 and a prospective study is currently underway to validate the usefulness of this in presurgical evaluation and surgical management. Ultimately, improvements in the surgical outcomes in this patient group will depend on better imaging, including visualisation of electrical abnormalities in 3D, reliable imaging integration and robust planning and implementation of intracranial EEG (figure 1).

Bottom Line: This review summarises exciting recent and forthcoming advances that will impact on the surgical management of epilepsy in the near future.This does not cover the current accepted diagnostic methodologies or surgical treatments that are routinely practiced today.The content of this review was derived from a PubMed literature search, using the key words 'Epilepsy Surgery', 'Neuromodulation', 'Neuroablation', 'Advances', between 2010 and November 2013.

View Article: PubMed Central - PubMed

Affiliation: Department of Clinical and Experimental Epilepsy, UCL Institute of Neurology, London, UK MRI Unit, Epilepsy Society, Chalfont St Peter, UK Department of Neurosurgery, National Hospital for Neurology and Neurosurgery, London, UK.

Show MeSH
Related in: MedlinePlus