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Prevalence of diabetic peripheral neuropathy in Iran: a systematic review and meta-analysis.

Sobhani S, Asayesh H, Sharifi F, Djalalinia S, Baradaran HR, Arzaghi SM, Mansourian M, Rezapoor A, Ansari H, Masoud MP, Qorbani M - J Diabetes Metab Disord (2014)

Bottom Line: Heterogeneity of reported prevalence's between studies was assessed by the Chi-square-based Q test and due to heterogeneity; overall prevalence of DPN was estimated using random-effect meta-analysis model.We found 304 records; from them a total of 21 studies comprising 5540 diabetic patients were included.In overall the prevalence of DPN estimated 53% (95% CI: 41-65) by using random-effect.

View Article: PubMed Central - PubMed

Affiliation: Non-Communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.

ABSTRACT
Diabetic peripheral neuropathy (DPN) is an important microvascular complication of diabetes mellitus (DM). It is a major contributor to foot ulceration and lower limb amputation in persons with DM and have also a significant negative effect on patient's quality of life. This meta-analysis reviews prevalence of DPN among patients with type 1 and 2 DM in Iran. Using PubMed and NLM Gateway (for MEDLINE), Institute of Scientific Information (ISI), and SCOPUS as the main international electronic data sources, and Iranmedex, Irandoc, and Scientific Information Database (SID), as the main domestic databases with systematic search capability, we systematically searched surveys, papers, and reports on the prevalence of DPN (between January 1991 to February 2013). Heterogeneity of reported prevalence's between studies was assessed by the Chi-square-based Q test and due to heterogeneity; overall prevalence of DPN was estimated using random-effect meta-analysis model. We found 304 records; from them a total of 21 studies comprising 5540 diabetic patients were included. The prevalence of diabetic neuropathy (reported) from 16% to 87%. In overall the prevalence of DPN estimated 53% (95% CI: 41-65) by using random-effect. This study show that the prevalence of DPN seems very high among the population with diabetes in Iran and more than half of the patients with DM has any type of diabetic neuropathy.

No MeSH data available.


Related in: MedlinePlus

Forest plot of DPN prevalence in Iran using random-effect model.
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Fig2: Forest plot of DPN prevalence in Iran using random-effect model.

Mentions: The results of heterogeneity test show sever heterogeneity among reported prevalence (I2: 99.8%, p-value < 0.01) and due to heterogeneity, random-effect meta-analysis was performed. Based on extracted article and random-effect meta-analysis; overall DPN estimated prevalence was 53% (95% CI: 41-65). Figure 2 present the forest plot of eligible articles for estimating DPN prevalence in Iran.Figure 2


Prevalence of diabetic peripheral neuropathy in Iran: a systematic review and meta-analysis.

Sobhani S, Asayesh H, Sharifi F, Djalalinia S, Baradaran HR, Arzaghi SM, Mansourian M, Rezapoor A, Ansari H, Masoud MP, Qorbani M - J Diabetes Metab Disord (2014)

Forest plot of DPN prevalence in Iran using random-effect model.
© Copyright Policy - open-access
Related In: Results  -  Collection

License 1 - License 2
Show All Figures
getmorefigures.php?uid=PMC4215018&req=5

Fig2: Forest plot of DPN prevalence in Iran using random-effect model.
Mentions: The results of heterogeneity test show sever heterogeneity among reported prevalence (I2: 99.8%, p-value < 0.01) and due to heterogeneity, random-effect meta-analysis was performed. Based on extracted article and random-effect meta-analysis; overall DPN estimated prevalence was 53% (95% CI: 41-65). Figure 2 present the forest plot of eligible articles for estimating DPN prevalence in Iran.Figure 2

Bottom Line: Heterogeneity of reported prevalence's between studies was assessed by the Chi-square-based Q test and due to heterogeneity; overall prevalence of DPN was estimated using random-effect meta-analysis model.We found 304 records; from them a total of 21 studies comprising 5540 diabetic patients were included.In overall the prevalence of DPN estimated 53% (95% CI: 41-65) by using random-effect.

View Article: PubMed Central - PubMed

Affiliation: Non-Communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.

ABSTRACT
Diabetic peripheral neuropathy (DPN) is an important microvascular complication of diabetes mellitus (DM). It is a major contributor to foot ulceration and lower limb amputation in persons with DM and have also a significant negative effect on patient's quality of life. This meta-analysis reviews prevalence of DPN among patients with type 1 and 2 DM in Iran. Using PubMed and NLM Gateway (for MEDLINE), Institute of Scientific Information (ISI), and SCOPUS as the main international electronic data sources, and Iranmedex, Irandoc, and Scientific Information Database (SID), as the main domestic databases with systematic search capability, we systematically searched surveys, papers, and reports on the prevalence of DPN (between January 1991 to February 2013). Heterogeneity of reported prevalence's between studies was assessed by the Chi-square-based Q test and due to heterogeneity; overall prevalence of DPN was estimated using random-effect meta-analysis model. We found 304 records; from them a total of 21 studies comprising 5540 diabetic patients were included. The prevalence of diabetic neuropathy (reported) from 16% to 87%. In overall the prevalence of DPN estimated 53% (95% CI: 41-65) by using random-effect. This study show that the prevalence of DPN seems very high among the population with diabetes in Iran and more than half of the patients with DM has any type of diabetic neuropathy.

No MeSH data available.


Related in: MedlinePlus