Limits...
Impaired aortic elasticity and diastolic functions are associated with findings of coronary computed tomographic angiography.

Ede H, ErkoƧ MF, Okur A, Erbay AR - Med. Sci. Monit. (2014)

Bottom Line: There was a significant correlation between ASI and EFV, but with a lower statistical value.Diastolic dysfunction was observed more commonly among patients with higher CACS and EFV.Epicardial fat volume was not as strong as CACS in reflecting aortic elasticity.

View Article: PubMed Central - PubMed

Affiliation: Department of Cardiology, Bozok University School of Medicine, Yozgat, Turkey.

ABSTRACT

Background: Coronary artery disease (CAD) is the leading cause of mortality and morbidity worldwide. Aortic elasticity and diastolic functions are helpful parameters in assessment of CAD. In this study we aimed to learn whether diastolic function and aortic elastic properties measured by echocardiography are associated with coronary calcium score (CACS), epicardial fat volume (EFV), and plaque area measured by coronary tomographic angiography.

Material and methods: We enrolled 106 consecutive patients suspected of CAD undergoing coronary CTA and transthoracic echocardiography in this prospective study. Total CACS, plaque area, and EFV were calculated via CTA. Aortic stiffness index (ASI) and aortic distensibility (AD) were measured via echocardiography.

Results: The patients with diastolic dysfunctions of any degree had significantly higher ASI, higher CACS, higher plaque area, and EFV. We found that as the ASI increases, the CACS and total coronary plaque area both increase, showing that there is a strong positive correlation between ASI, CACS, and total coronary plaque area. There was a significant correlation between ASI and EFV, but with a lower statistical value.

Conclusions: Aortic elasticity was correlated with CACS and plaque area. Diastolic dysfunction was observed more commonly among patients with higher CACS and EFV. Epicardial fat volume was not as strong as CACS in reflecting aortic elasticity.

Show MeSH

Related in: MedlinePlus

Evaluation of epicardial fat volume using a multiplanar reformat and volume-rendering techniques (VRTs).
© Copyright Policy
Related In: Results  -  Collection


getmorefigures.php?uid=PMC4214696&req=5

f1-medscimonit-20-2061: Evaluation of epicardial fat volume using a multiplanar reformat and volume-rendering techniques (VRTs).

Mentions: All images were evaluated for volumetric analysis at the work station (Extended Brilliance, Version 3.5.0.2254; Philips Medical System) using multi-planar reformat and volume-rendering techniques (VRTs). Coronary calcium score, epicardial fat volume, and coronary plaque volume were independently determined by 2 radiologists and were averaged. Epicardial fat, defined as the adipose tissue within the visceral layer of the pericardium, was measured at each axial noncontrast CT slice by manually tracing the pericardium; the total epicardial fat volume was then calculated by slice summation of the single-slice data (Figure 1).


Impaired aortic elasticity and diastolic functions are associated with findings of coronary computed tomographic angiography.

Ede H, ErkoƧ MF, Okur A, Erbay AR - Med. Sci. Monit. (2014)

Evaluation of epicardial fat volume using a multiplanar reformat and volume-rendering techniques (VRTs).
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC4214696&req=5

f1-medscimonit-20-2061: Evaluation of epicardial fat volume using a multiplanar reformat and volume-rendering techniques (VRTs).
Mentions: All images were evaluated for volumetric analysis at the work station (Extended Brilliance, Version 3.5.0.2254; Philips Medical System) using multi-planar reformat and volume-rendering techniques (VRTs). Coronary calcium score, epicardial fat volume, and coronary plaque volume were independently determined by 2 radiologists and were averaged. Epicardial fat, defined as the adipose tissue within the visceral layer of the pericardium, was measured at each axial noncontrast CT slice by manually tracing the pericardium; the total epicardial fat volume was then calculated by slice summation of the single-slice data (Figure 1).

Bottom Line: There was a significant correlation between ASI and EFV, but with a lower statistical value.Diastolic dysfunction was observed more commonly among patients with higher CACS and EFV.Epicardial fat volume was not as strong as CACS in reflecting aortic elasticity.

View Article: PubMed Central - PubMed

Affiliation: Department of Cardiology, Bozok University School of Medicine, Yozgat, Turkey.

ABSTRACT

Background: Coronary artery disease (CAD) is the leading cause of mortality and morbidity worldwide. Aortic elasticity and diastolic functions are helpful parameters in assessment of CAD. In this study we aimed to learn whether diastolic function and aortic elastic properties measured by echocardiography are associated with coronary calcium score (CACS), epicardial fat volume (EFV), and plaque area measured by coronary tomographic angiography.

Material and methods: We enrolled 106 consecutive patients suspected of CAD undergoing coronary CTA and transthoracic echocardiography in this prospective study. Total CACS, plaque area, and EFV were calculated via CTA. Aortic stiffness index (ASI) and aortic distensibility (AD) were measured via echocardiography.

Results: The patients with diastolic dysfunctions of any degree had significantly higher ASI, higher CACS, higher plaque area, and EFV. We found that as the ASI increases, the CACS and total coronary plaque area both increase, showing that there is a strong positive correlation between ASI, CACS, and total coronary plaque area. There was a significant correlation between ASI and EFV, but with a lower statistical value.

Conclusions: Aortic elasticity was correlated with CACS and plaque area. Diastolic dysfunction was observed more commonly among patients with higher CACS and EFV. Epicardial fat volume was not as strong as CACS in reflecting aortic elasticity.

Show MeSH
Related in: MedlinePlus