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Identification of primary thyroid lymphoma with medical imaging: A case report and review of the literature.

Wang JH, Chen L, Ren K - Oncol Lett (2014)

Bottom Line: On color Doppler ultrasound, the PTL was shown as a significantly enlarged thyroid with reduced gland echoes.PTL exhibits specific features on medical imaging that aid in distinguishing it from other thyroid diseases.PTL exhibits specific features on medical imaging that aid in distinguishing PTL from other thyroid diseases, which may aid the support for clinical diagnosis and improve the clinical accuracy.

View Article: PubMed Central - PubMed

Affiliation: Department of Radiology, The First Hospital of Jilin University, Changchun, Jilin 130021, P.R. China ; Department of Radiology, Jilin Central Hospital, Jilin City, Jilin 132000, P.R. China.

ABSTRACT
Primary thyroid lymphoma (PTL) is a rare thyroid malignancy. Clinical diagnosis of PTL may not be easily established based on imaging studies, as the imaging features of PTL are similar to those of lymphocytic thyroiditis and primary thyroid cancer. The present study describes the case of a patient who was confirmed to have PTL by intra-operative pathological diagnosis. On color Doppler ultrasound, the PTL was shown as a significantly enlarged thyroid with reduced gland echoes. Color Doppler flow imaging showed increased blood flow. By computed tomography, the thyroid was revealed to be enlarged with reduced tissue density, particularly in the left lobe and the isthmus. In addition, calcified spots and swollen lymph nodes were evident. The clinical history of the patient was obtained and the imaging results were retrospectively analyzed. The imaging features of PTL were investigated through reviewing the literature. PTL exhibits specific features on medical imaging that aid in distinguishing it from other thyroid diseases. PTL exhibits specific features on medical imaging that aid in distinguishing PTL from other thyroid diseases, which may aid the support for clinical diagnosis and improve the clinical accuracy.

No MeSH data available.


Related in: MedlinePlus

Color Doppler ultrasound demonstrating (A) non-uniform hypoechoic signals and an indication of calcified spots (white arrows). (B) Color Doppler flow imaging indicted increased blood flow signals.
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f1-ol-08-06-2505: Color Doppler ultrasound demonstrating (A) non-uniform hypoechoic signals and an indication of calcified spots (white arrows). (B) Color Doppler flow imaging indicted increased blood flow signals.

Mentions: A neck color Doppler ultrasound showed a significantly enlarged left lobe and isthmus of the thyroid (Fig. 1). The gland was non-uniformly hypoechoic, with an indication of calcified spots. Also, the trachea was pressed to the right. Color Doppler flow imaging showed increased blood flow signals. Computed tomography (CT) in the transverse view (Fig. 2A) revealed a significantly enlarged thyroid, particularly in the left lobe and isthmus, with reduced thyroid tissue density and calcified spots. The coronal and sagittal CT views (Fig. 2B and C) showed that the lesion extended from the upper level of the third cervical vertebra to the arterial arch. The largest lesion section was approximately 8.5×8.7 cm, with a longitudinal dimension of ~9.4 cm. The trachea, esophagus and soft tissues in the left neck were under pressure and displaced toward the right side. Soft tissue density shadows of 0.7–3.0 cm in diameter were observed medial to the sternocleidomastoid muscle. Enlarged abdominal and retroperitoneal lymph nodes were not detected on the abdominal CT image.


Identification of primary thyroid lymphoma with medical imaging: A case report and review of the literature.

Wang JH, Chen L, Ren K - Oncol Lett (2014)

Color Doppler ultrasound demonstrating (A) non-uniform hypoechoic signals and an indication of calcified spots (white arrows). (B) Color Doppler flow imaging indicted increased blood flow signals.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4214466&req=5

f1-ol-08-06-2505: Color Doppler ultrasound demonstrating (A) non-uniform hypoechoic signals and an indication of calcified spots (white arrows). (B) Color Doppler flow imaging indicted increased blood flow signals.
Mentions: A neck color Doppler ultrasound showed a significantly enlarged left lobe and isthmus of the thyroid (Fig. 1). The gland was non-uniformly hypoechoic, with an indication of calcified spots. Also, the trachea was pressed to the right. Color Doppler flow imaging showed increased blood flow signals. Computed tomography (CT) in the transverse view (Fig. 2A) revealed a significantly enlarged thyroid, particularly in the left lobe and isthmus, with reduced thyroid tissue density and calcified spots. The coronal and sagittal CT views (Fig. 2B and C) showed that the lesion extended from the upper level of the third cervical vertebra to the arterial arch. The largest lesion section was approximately 8.5×8.7 cm, with a longitudinal dimension of ~9.4 cm. The trachea, esophagus and soft tissues in the left neck were under pressure and displaced toward the right side. Soft tissue density shadows of 0.7–3.0 cm in diameter were observed medial to the sternocleidomastoid muscle. Enlarged abdominal and retroperitoneal lymph nodes were not detected on the abdominal CT image.

Bottom Line: On color Doppler ultrasound, the PTL was shown as a significantly enlarged thyroid with reduced gland echoes.PTL exhibits specific features on medical imaging that aid in distinguishing it from other thyroid diseases.PTL exhibits specific features on medical imaging that aid in distinguishing PTL from other thyroid diseases, which may aid the support for clinical diagnosis and improve the clinical accuracy.

View Article: PubMed Central - PubMed

Affiliation: Department of Radiology, The First Hospital of Jilin University, Changchun, Jilin 130021, P.R. China ; Department of Radiology, Jilin Central Hospital, Jilin City, Jilin 132000, P.R. China.

ABSTRACT
Primary thyroid lymphoma (PTL) is a rare thyroid malignancy. Clinical diagnosis of PTL may not be easily established based on imaging studies, as the imaging features of PTL are similar to those of lymphocytic thyroiditis and primary thyroid cancer. The present study describes the case of a patient who was confirmed to have PTL by intra-operative pathological diagnosis. On color Doppler ultrasound, the PTL was shown as a significantly enlarged thyroid with reduced gland echoes. Color Doppler flow imaging showed increased blood flow. By computed tomography, the thyroid was revealed to be enlarged with reduced tissue density, particularly in the left lobe and the isthmus. In addition, calcified spots and swollen lymph nodes were evident. The clinical history of the patient was obtained and the imaging results were retrospectively analyzed. The imaging features of PTL were investigated through reviewing the literature. PTL exhibits specific features on medical imaging that aid in distinguishing it from other thyroid diseases. PTL exhibits specific features on medical imaging that aid in distinguishing PTL from other thyroid diseases, which may aid the support for clinical diagnosis and improve the clinical accuracy.

No MeSH data available.


Related in: MedlinePlus