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Takotsubo's Cardiomyopathy in a Patient with Kartagener's Syndrome.

Dominguez LW, Doggette RP, Gonzalez-Ibarra F, Shaik IH, Syed AK - Case Rep Med (2014)

Bottom Line: ECG and troponins indicated an acute myocardial infarction.Ventricular contraction and EF were restored in 4 weeks.Chronic lung disease may contribute to the development of Takotsubo's cardiomyopathy, which is a documented yet not fully understood phenomenon.

View Article: PubMed Central - PubMed

Affiliation: Department of Internal Medicine, Jersey City Medical Center, 355 Grand Street, Jersey City, NJ 07302, USA ; St. George's University School of Medicine, St. George's, Grenada.

ABSTRACT
A 46-year-old African-American male with past medical history significant for Kartagener's syndrome, essential hypertension, and HIV presented with acute chest pain. ECG and troponins indicated an acute myocardial infarction. Ventriculography confirmed dyskinesia of the left ventricle, with an EF of 25%. However the coronary catheterization showed nonobstructed coronaries. Ventricular contraction and EF were restored in 4 weeks. To our knowledge, this is the first incidence of Takotsubo's reported in a young patient with Kartagener's syndrome. Chronic lung disease may contribute to the development of Takotsubo's cardiomyopathy, which is a documented yet not fully understood phenomenon.

No MeSH data available.


Related in: MedlinePlus

Ventriculograms showing the heart at end diastolic volume (a) and at end systolic volume (b), revealing apical ballooning seen in Takotsubo's. Outlining used for enhanced visualization of the ventricle wall for comparison.
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fig3: Ventriculograms showing the heart at end diastolic volume (a) and at end systolic volume (b), revealing apical ballooning seen in Takotsubo's. Outlining used for enhanced visualization of the ventricle wall for comparison.

Mentions: The patient was treated with aspirin, clopidogrel, statins, beta-blockers, ACE inhibitors, and heparin for acute coronary syndrome. Nitroglycerine and morphine were also administered. Echocardiography showed dyskinesia of the left ventricular apex. Subsequent coronary angiography revealed nonobstructive coronaries, moderate dyskinesia of the apex, and mild dyskinesia of the anterolateral wall with the ejection fraction estimated at 25% on left ventriculogram (Figures 3(a) and 3(b)). The diagnosis of Takotsubo's cardiomyopathy was made based on Mayo Clinic criteria [12]. The patient was discharged 5 days later on aspirin, ACE inhibitors, beta-blockers, and statins along with a LifeVest and follow-ups scheduled at 2 and 4 weeks.


Takotsubo's Cardiomyopathy in a Patient with Kartagener's Syndrome.

Dominguez LW, Doggette RP, Gonzalez-Ibarra F, Shaik IH, Syed AK - Case Rep Med (2014)

Ventriculograms showing the heart at end diastolic volume (a) and at end systolic volume (b), revealing apical ballooning seen in Takotsubo's. Outlining used for enhanced visualization of the ventricle wall for comparison.
© Copyright Policy - open-access
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC4214047&req=5

fig3: Ventriculograms showing the heart at end diastolic volume (a) and at end systolic volume (b), revealing apical ballooning seen in Takotsubo's. Outlining used for enhanced visualization of the ventricle wall for comparison.
Mentions: The patient was treated with aspirin, clopidogrel, statins, beta-blockers, ACE inhibitors, and heparin for acute coronary syndrome. Nitroglycerine and morphine were also administered. Echocardiography showed dyskinesia of the left ventricular apex. Subsequent coronary angiography revealed nonobstructive coronaries, moderate dyskinesia of the apex, and mild dyskinesia of the anterolateral wall with the ejection fraction estimated at 25% on left ventriculogram (Figures 3(a) and 3(b)). The diagnosis of Takotsubo's cardiomyopathy was made based on Mayo Clinic criteria [12]. The patient was discharged 5 days later on aspirin, ACE inhibitors, beta-blockers, and statins along with a LifeVest and follow-ups scheduled at 2 and 4 weeks.

Bottom Line: ECG and troponins indicated an acute myocardial infarction.Ventricular contraction and EF were restored in 4 weeks.Chronic lung disease may contribute to the development of Takotsubo's cardiomyopathy, which is a documented yet not fully understood phenomenon.

View Article: PubMed Central - PubMed

Affiliation: Department of Internal Medicine, Jersey City Medical Center, 355 Grand Street, Jersey City, NJ 07302, USA ; St. George's University School of Medicine, St. George's, Grenada.

ABSTRACT
A 46-year-old African-American male with past medical history significant for Kartagener's syndrome, essential hypertension, and HIV presented with acute chest pain. ECG and troponins indicated an acute myocardial infarction. Ventriculography confirmed dyskinesia of the left ventricle, with an EF of 25%. However the coronary catheterization showed nonobstructed coronaries. Ventricular contraction and EF were restored in 4 weeks. To our knowledge, this is the first incidence of Takotsubo's reported in a young patient with Kartagener's syndrome. Chronic lung disease may contribute to the development of Takotsubo's cardiomyopathy, which is a documented yet not fully understood phenomenon.

No MeSH data available.


Related in: MedlinePlus