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Process standardization and characterization of Rajata Sindura.

Gokarn RA, Gokarn SR, Hiremath SG - Ayu (2014)

Bottom Line: Pharmaceutical standardization and characterization of Rajata Sindura.This Kajjali was processed by Kupipakwa method.RS was prepared in 33 h with 20.25% yield.

View Article: PubMed Central - PubMed

Affiliation: Department of Rasa Shastra and Bhaishjya Kalpana, Mahatma Gandhi Ayurved College, Hospital and Research Centre, Wardha, Maharashtra, India.

ABSTRACT

Background: Rajata Sindura (RS) is a mercurial preparation, known for its properties like Rasayana (rejuvinating), Balya (strengthening), Vrushya (aphrodisiac), Medhya (increasing intellect) and can cure various diseases when used with appropriate adjuvant. It is prepared with Hingulottha Parada (purified mercury), Shuddha Gandhaka (purified sulfur) and Shuddha Rajata (purified silver) in a proportion of 1:1:4. Process standardization and characterization of RS are not reported until date.

Aim: Pharmaceutical standardization and characterization of Rajata Sindura.

Materials and methods: Purified mercury and silver were triturated to form amalgam, followed by the addition of purified sulfur to prepare Kajjali and lavigated with Vatankura (leaf buds of Ficus benghalensis Linn.) swarasa (juice). This Kajjali was processed by Kupipakwa method.

Results and conclusion: RS was prepared in 33 h with 20.25% yield. Scanning electron microscope coupled with energy dispersive spectroscopy analysis has shown Mercury 86.21%, sulfur 13.27% as major elements; iron, calcium, potassium, magnesium and silver were other detected minor elements. X-ray diffraction report revealed the chemical nature of RS as HgS compound, having cubic crystal structure.

No MeSH data available.


Related in: MedlinePlus

Temperature graph of Rajata Sindura preparation
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Figure 9: Temperature graph of Rajata Sindura preparation

Mentions: Kajjali was filled in the Kupi and kept in the Valuka Yantra [Figure 7], which was placed in the Bhatti [Figure 8]. Pyrometer was placed at the bottom of Kupi in Valuka Yantra. Fire was set; temperature reading was carried out at regular intervals of 30 min. Kramagni (gradual rise of temperature) was maintained [Graph 1]. Corking was done after complete cessation of flame [Figure 9] and observing the Siddhi Lakshanas, like complete cessation of sulfur fumes, Suryodaya Lakshana (red appearance of the bottom) [Figure 10] and positive copper coin test, etc., [Table 5].


Process standardization and characterization of Rajata Sindura.

Gokarn RA, Gokarn SR, Hiremath SG - Ayu (2014)

Temperature graph of Rajata Sindura preparation
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4213972&req=5

Figure 9: Temperature graph of Rajata Sindura preparation
Mentions: Kajjali was filled in the Kupi and kept in the Valuka Yantra [Figure 7], which was placed in the Bhatti [Figure 8]. Pyrometer was placed at the bottom of Kupi in Valuka Yantra. Fire was set; temperature reading was carried out at regular intervals of 30 min. Kramagni (gradual rise of temperature) was maintained [Graph 1]. Corking was done after complete cessation of flame [Figure 9] and observing the Siddhi Lakshanas, like complete cessation of sulfur fumes, Suryodaya Lakshana (red appearance of the bottom) [Figure 10] and positive copper coin test, etc., [Table 5].

Bottom Line: Pharmaceutical standardization and characterization of Rajata Sindura.This Kajjali was processed by Kupipakwa method.RS was prepared in 33 h with 20.25% yield.

View Article: PubMed Central - PubMed

Affiliation: Department of Rasa Shastra and Bhaishjya Kalpana, Mahatma Gandhi Ayurved College, Hospital and Research Centre, Wardha, Maharashtra, India.

ABSTRACT

Background: Rajata Sindura (RS) is a mercurial preparation, known for its properties like Rasayana (rejuvinating), Balya (strengthening), Vrushya (aphrodisiac), Medhya (increasing intellect) and can cure various diseases when used with appropriate adjuvant. It is prepared with Hingulottha Parada (purified mercury), Shuddha Gandhaka (purified sulfur) and Shuddha Rajata (purified silver) in a proportion of 1:1:4. Process standardization and characterization of RS are not reported until date.

Aim: Pharmaceutical standardization and characterization of Rajata Sindura.

Materials and methods: Purified mercury and silver were triturated to form amalgam, followed by the addition of purified sulfur to prepare Kajjali and lavigated with Vatankura (leaf buds of Ficus benghalensis Linn.) swarasa (juice). This Kajjali was processed by Kupipakwa method.

Results and conclusion: RS was prepared in 33 h with 20.25% yield. Scanning electron microscope coupled with energy dispersive spectroscopy analysis has shown Mercury 86.21%, sulfur 13.27% as major elements; iron, calcium, potassium, magnesium and silver were other detected minor elements. X-ray diffraction report revealed the chemical nature of RS as HgS compound, having cubic crystal structure.

No MeSH data available.


Related in: MedlinePlus