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Process standardization and characterization of Rajata Sindura.

Gokarn RA, Gokarn SR, Hiremath SG - Ayu (2014)

Bottom Line: Pharmaceutical standardization and characterization of Rajata Sindura.This Kajjali was processed by Kupipakwa method.RS was prepared in 33 h with 20.25% yield.

View Article: PubMed Central - PubMed

Affiliation: Department of Rasa Shastra and Bhaishjya Kalpana, Mahatma Gandhi Ayurved College, Hospital and Research Centre, Wardha, Maharashtra, India.

ABSTRACT

Background: Rajata Sindura (RS) is a mercurial preparation, known for its properties like Rasayana (rejuvinating), Balya (strengthening), Vrushya (aphrodisiac), Medhya (increasing intellect) and can cure various diseases when used with appropriate adjuvant. It is prepared with Hingulottha Parada (purified mercury), Shuddha Gandhaka (purified sulfur) and Shuddha Rajata (purified silver) in a proportion of 1:1:4. Process standardization and characterization of RS are not reported until date.

Aim: Pharmaceutical standardization and characterization of Rajata Sindura.

Materials and methods: Purified mercury and silver were triturated to form amalgam, followed by the addition of purified sulfur to prepare Kajjali and lavigated with Vatankura (leaf buds of Ficus benghalensis Linn.) swarasa (juice). This Kajjali was processed by Kupipakwa method.

Results and conclusion: RS was prepared in 33 h with 20.25% yield. Scanning electron microscope coupled with energy dispersive spectroscopy analysis has shown Mercury 86.21%, sulfur 13.27% as major elements; iron, calcium, potassium, magnesium and silver were other detected minor elements. X-ray diffraction report revealed the chemical nature of RS as HgS compound, having cubic crystal structure.

No MeSH data available.


Related in: MedlinePlus

Purified mercury
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Figure 1: Purified mercury

Mentions: Mercury was extracted from cinnabar by Nadayantra method.[8] Initially, cinnabar was levigated with Nimbu Swarasa (juice of C. limon) and fine powder of triturated cinnabar was spread uniformly over a cotton cloth (equal to the weight of cinnabar), tied with thread and ignited. While igniting an earthen pot was placed inverted to facilitate the collection of mercury. Thus obtained mercury was collected carefully and filtered through four folded cloth [Table 1, Figure 1]. Sulfur was purified by Dhalana method.[9] Impure sulfur was taken in a stainless steel container along with Ghrita (1/4 part) and melted over mild flame. A muslin cloth smeared with Ghrita was tied to the mouth of the container containing milk. As soon as sulfur melted, the mixture was poured through the cloth into the container containing milk. Thus obtained sulfur was washed with hot water and dried. The above process was repeated for two more times [Table 2, Figure 2]. Samanya Shodhana of Rajata[10] was carried out by quenching in different liquids like Tila Taila (sesum oil), Takra (butter milk), Gomutra (cow's urine), Aranala (sour gruel prepared out of rice), and Kulattha Kwatha (decoction of Vigna unquiculata Linn.) as per the classical reference. Vishesha Shodhana[11] was done by Nirvapa (heating and dipping) in Nimbu Swarasa for 7 times [Table 3, Figure 3].


Process standardization and characterization of Rajata Sindura.

Gokarn RA, Gokarn SR, Hiremath SG - Ayu (2014)

Purified mercury
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4213972&req=5

Figure 1: Purified mercury
Mentions: Mercury was extracted from cinnabar by Nadayantra method.[8] Initially, cinnabar was levigated with Nimbu Swarasa (juice of C. limon) and fine powder of triturated cinnabar was spread uniformly over a cotton cloth (equal to the weight of cinnabar), tied with thread and ignited. While igniting an earthen pot was placed inverted to facilitate the collection of mercury. Thus obtained mercury was collected carefully and filtered through four folded cloth [Table 1, Figure 1]. Sulfur was purified by Dhalana method.[9] Impure sulfur was taken in a stainless steel container along with Ghrita (1/4 part) and melted over mild flame. A muslin cloth smeared with Ghrita was tied to the mouth of the container containing milk. As soon as sulfur melted, the mixture was poured through the cloth into the container containing milk. Thus obtained sulfur was washed with hot water and dried. The above process was repeated for two more times [Table 2, Figure 2]. Samanya Shodhana of Rajata[10] was carried out by quenching in different liquids like Tila Taila (sesum oil), Takra (butter milk), Gomutra (cow's urine), Aranala (sour gruel prepared out of rice), and Kulattha Kwatha (decoction of Vigna unquiculata Linn.) as per the classical reference. Vishesha Shodhana[11] was done by Nirvapa (heating and dipping) in Nimbu Swarasa for 7 times [Table 3, Figure 3].

Bottom Line: Pharmaceutical standardization and characterization of Rajata Sindura.This Kajjali was processed by Kupipakwa method.RS was prepared in 33 h with 20.25% yield.

View Article: PubMed Central - PubMed

Affiliation: Department of Rasa Shastra and Bhaishjya Kalpana, Mahatma Gandhi Ayurved College, Hospital and Research Centre, Wardha, Maharashtra, India.

ABSTRACT

Background: Rajata Sindura (RS) is a mercurial preparation, known for its properties like Rasayana (rejuvinating), Balya (strengthening), Vrushya (aphrodisiac), Medhya (increasing intellect) and can cure various diseases when used with appropriate adjuvant. It is prepared with Hingulottha Parada (purified mercury), Shuddha Gandhaka (purified sulfur) and Shuddha Rajata (purified silver) in a proportion of 1:1:4. Process standardization and characterization of RS are not reported until date.

Aim: Pharmaceutical standardization and characterization of Rajata Sindura.

Materials and methods: Purified mercury and silver were triturated to form amalgam, followed by the addition of purified sulfur to prepare Kajjali and lavigated with Vatankura (leaf buds of Ficus benghalensis Linn.) swarasa (juice). This Kajjali was processed by Kupipakwa method.

Results and conclusion: RS was prepared in 33 h with 20.25% yield. Scanning electron microscope coupled with energy dispersive spectroscopy analysis has shown Mercury 86.21%, sulfur 13.27% as major elements; iron, calcium, potassium, magnesium and silver were other detected minor elements. X-ray diffraction report revealed the chemical nature of RS as HgS compound, having cubic crystal structure.

No MeSH data available.


Related in: MedlinePlus