Limits...
Quality control evaluation of Keshamasi, Keshanjana and Keshamasi eye ointment.

Dhiman KS, Shukla VJ, Bhalodia NR, Sharma VR - Ayu (2014)

Bottom Line: Lead and zinc were present in most of the samples; while all samples are were free from microbial contamination.As no standards are available to compare the results of the current study, the observations cannot be compared.Thus the profile generated in the current study can be considered as standard to refer in future studies.

View Article: PubMed Central - PubMed

Affiliation: Department of Shalakya Tantra, Institute for Post Graduate Teaching and Research in Ayurveda, Gujarat Ayurved University, Jamnagar, India.

ABSTRACT

Background: Keshanjana (collyrium) is a well known Ayurvedic preparation prepared out of Keshamasi (ash prepared by scalp hairs) mixed with Goghrita (cow's ghee). This medicine is indicated for the treatment of Shushkakshipaka (dry eye syndrome) in the classical literature of Ayurveda; hence, it was under taken for standardization and clinical evaluation in an extra-mural research project from Central Council for Research in Ayurvedic Sciences, Department of AYUSH, New Delhi.

Aim: To develop standard quality parameters for the Keshamasi, Keshanjana and Keshamasi ointment.

Materials and methods: Scalp hairs of male and females collected from saloons were converted to classical Masi Kalpana and mixed with cow ghee and petrolatum in the ratio of 1:5 to prepare the Keshanjana and Keshamasi ointment respectively. Standard Operation Procedure (SOP) were adopted and recorded accordingly. The raw material, furnished products and plain Goghrita were subjected for quality control parameters i.e., physico-chemical evaluation, anti-microbial study, particle size analysis, heavy metal analysis through inductive couple plasma spectroscopy with high performance thin layer liquid chromatography fingerprints.

Results: Rancidity was negative in all the samples, indicating that the physico-chemical parameters are in acceptable range. Lead and zinc were present in most of the samples; while all samples are were free from microbial contamination.

Conclusion: As no standards are available to compare the results of the current study, the observations cannot be compared. Thus the profile generated in the current study can be considered as standard to refer in future studies.

No MeSH data available.


Related in: MedlinePlus

3D image of all tracks at 366 nm
© Copyright Policy - open-access
Related In: Results  -  Collection

License
getmorefigures.php?uid=PMC4213971&req=5

Figure 1: 3D image of all tracks at 366 nm

Mentions: In the chromatogram of unsaponifiable matter of cow ghee and formulated finished products; Rf values of spots were noted under different conditions. Then all tracks were scanned under 254 nm and 366 nm and also post chromatographic derivation through spray methanolic sulphuric acid and Rf are mentioned in the table. Different tracks are represented at the wavelength of 254 nm and 366 nm [Table 10 and Figure 1].


Quality control evaluation of Keshamasi, Keshanjana and Keshamasi eye ointment.

Dhiman KS, Shukla VJ, Bhalodia NR, Sharma VR - Ayu (2014)

3D image of all tracks at 366 nm
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4213971&req=5

Figure 1: 3D image of all tracks at 366 nm
Mentions: In the chromatogram of unsaponifiable matter of cow ghee and formulated finished products; Rf values of spots were noted under different conditions. Then all tracks were scanned under 254 nm and 366 nm and also post chromatographic derivation through spray methanolic sulphuric acid and Rf are mentioned in the table. Different tracks are represented at the wavelength of 254 nm and 366 nm [Table 10 and Figure 1].

Bottom Line: Lead and zinc were present in most of the samples; while all samples are were free from microbial contamination.As no standards are available to compare the results of the current study, the observations cannot be compared.Thus the profile generated in the current study can be considered as standard to refer in future studies.

View Article: PubMed Central - PubMed

Affiliation: Department of Shalakya Tantra, Institute for Post Graduate Teaching and Research in Ayurveda, Gujarat Ayurved University, Jamnagar, India.

ABSTRACT

Background: Keshanjana (collyrium) is a well known Ayurvedic preparation prepared out of Keshamasi (ash prepared by scalp hairs) mixed with Goghrita (cow's ghee). This medicine is indicated for the treatment of Shushkakshipaka (dry eye syndrome) in the classical literature of Ayurveda; hence, it was under taken for standardization and clinical evaluation in an extra-mural research project from Central Council for Research in Ayurvedic Sciences, Department of AYUSH, New Delhi.

Aim: To develop standard quality parameters for the Keshamasi, Keshanjana and Keshamasi ointment.

Materials and methods: Scalp hairs of male and females collected from saloons were converted to classical Masi Kalpana and mixed with cow ghee and petrolatum in the ratio of 1:5 to prepare the Keshanjana and Keshamasi ointment respectively. Standard Operation Procedure (SOP) were adopted and recorded accordingly. The raw material, furnished products and plain Goghrita were subjected for quality control parameters i.e., physico-chemical evaluation, anti-microbial study, particle size analysis, heavy metal analysis through inductive couple plasma spectroscopy with high performance thin layer liquid chromatography fingerprints.

Results: Rancidity was negative in all the samples, indicating that the physico-chemical parameters are in acceptable range. Lead and zinc were present in most of the samples; while all samples are were free from microbial contamination.

Conclusion: As no standards are available to compare the results of the current study, the observations cannot be compared. Thus the profile generated in the current study can be considered as standard to refer in future studies.

No MeSH data available.


Related in: MedlinePlus