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A customized bolus produced using a 3-dimensional printer for radiotherapy.

Kim SW, Shin HJ, Kay CS, Son SH - PLoS ONE (2014)

Bottom Line: Boluses are used in high-energy radiotherapy in order to overcome the skin sparing effect.In practice though, commonly used flat boluses fail to make a perfect contact with the irregular surface of the patient's skin, resulting in air gaps.The dosimetric parameters of the resulting 3D printed flat bolus showed that it was a useful dose escalating material, equivalent to a commercially available flat bolus.

View Article: PubMed Central - PubMed

Affiliation: Radiation Oncology, Incheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.

ABSTRACT

Objective: Boluses are used in high-energy radiotherapy in order to overcome the skin sparing effect. In practice though, commonly used flat boluses fail to make a perfect contact with the irregular surface of the patient's skin, resulting in air gaps. Hence, we fabricated a customized bolus using a 3-dimensional (3D) printer and evaluated its feasibility for radiotherapy.

Methods: We designed two kinds of bolus for production on a 3D printer, one of which was the 3D printed flat bolus for the Blue water phantom and the other was a 3D printed customized bolus for the RANDO phantom. The 3D printed flat bolus was fabricated to verify its physical quality. The resulting 3D printed flat bolus was evaluated by assessing dosimetric parameters such as D1.5 cm, D5 cm, and D10 cm. The 3D printed customized bolus was then fabricated, and its quality and clinical feasibility were evaluated by visual inspection and by assessing dosimetric parameters such as Dmax, Dmin, Dmean, D90%, and V90%.

Results: The dosimetric parameters of the resulting 3D printed flat bolus showed that it was a useful dose escalating material, equivalent to a commercially available flat bolus. Analysis of the dosimetric parameters of the 3D printed customized bolus demonstrated that it is provided good dose escalation and good contact with the irregular surface of the RANDO phantom.

Conclusions: A customized bolus produced using a 3D printer could potentially replace commercially available flat boluses.

Show MeSH
Percent depth dose (PDD) at the central axis and the dose volume histogram (DVH) of each plan from the RANDO phantom study.(a) PDD, (b) DVH.
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pone-0110746-g006: Percent depth dose (PDD) at the central axis and the dose volume histogram (DVH) of each plan from the RANDO phantom study.(a) PDD, (b) DVH.

Mentions: For the RANDO phantom study, the dose distributions of the plans without a bolus and with the 3D printed customized bolus on the RANDO phantom are shown in Figure 5, indicating that the 3D printed customized bolus is a good buildup material. For the plan without a bolus, the Dmax, Dmin, Dmean, D90%, and V90% of the target volume were 101.3%, 25.4%, 86.4%, 62.7%, and 53.5%, respectively. This suggests that the plan without a bolus cannot fully deliver the prescribed dose to the target volume. However, when the 3D printed customized bolus was added, the Dmax, Dmin, Dmean, D90%, and V90% of the target volume were 101.3%, 90.0%, 95.5%, 91.6%, and 100.0%, respectively, indicating effective dose coverage. Each dosimetric parameter is shown in Table 2, and the PDD and DVH of both plans are illustrated in Figure 6. Both the PDD and DVH show sufficient dose escalation in the target volume with the 3D printed customized bolus.


A customized bolus produced using a 3-dimensional printer for radiotherapy.

Kim SW, Shin HJ, Kay CS, Son SH - PLoS ONE (2014)

Percent depth dose (PDD) at the central axis and the dose volume histogram (DVH) of each plan from the RANDO phantom study.(a) PDD, (b) DVH.
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4206462&req=5

pone-0110746-g006: Percent depth dose (PDD) at the central axis and the dose volume histogram (DVH) of each plan from the RANDO phantom study.(a) PDD, (b) DVH.
Mentions: For the RANDO phantom study, the dose distributions of the plans without a bolus and with the 3D printed customized bolus on the RANDO phantom are shown in Figure 5, indicating that the 3D printed customized bolus is a good buildup material. For the plan without a bolus, the Dmax, Dmin, Dmean, D90%, and V90% of the target volume were 101.3%, 25.4%, 86.4%, 62.7%, and 53.5%, respectively. This suggests that the plan without a bolus cannot fully deliver the prescribed dose to the target volume. However, when the 3D printed customized bolus was added, the Dmax, Dmin, Dmean, D90%, and V90% of the target volume were 101.3%, 90.0%, 95.5%, 91.6%, and 100.0%, respectively, indicating effective dose coverage. Each dosimetric parameter is shown in Table 2, and the PDD and DVH of both plans are illustrated in Figure 6. Both the PDD and DVH show sufficient dose escalation in the target volume with the 3D printed customized bolus.

Bottom Line: Boluses are used in high-energy radiotherapy in order to overcome the skin sparing effect.In practice though, commonly used flat boluses fail to make a perfect contact with the irregular surface of the patient's skin, resulting in air gaps.The dosimetric parameters of the resulting 3D printed flat bolus showed that it was a useful dose escalating material, equivalent to a commercially available flat bolus.

View Article: PubMed Central - PubMed

Affiliation: Radiation Oncology, Incheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.

ABSTRACT

Objective: Boluses are used in high-energy radiotherapy in order to overcome the skin sparing effect. In practice though, commonly used flat boluses fail to make a perfect contact with the irregular surface of the patient's skin, resulting in air gaps. Hence, we fabricated a customized bolus using a 3-dimensional (3D) printer and evaluated its feasibility for radiotherapy.

Methods: We designed two kinds of bolus for production on a 3D printer, one of which was the 3D printed flat bolus for the Blue water phantom and the other was a 3D printed customized bolus for the RANDO phantom. The 3D printed flat bolus was fabricated to verify its physical quality. The resulting 3D printed flat bolus was evaluated by assessing dosimetric parameters such as D1.5 cm, D5 cm, and D10 cm. The 3D printed customized bolus was then fabricated, and its quality and clinical feasibility were evaluated by visual inspection and by assessing dosimetric parameters such as Dmax, Dmin, Dmean, D90%, and V90%.

Results: The dosimetric parameters of the resulting 3D printed flat bolus showed that it was a useful dose escalating material, equivalent to a commercially available flat bolus. Analysis of the dosimetric parameters of the 3D printed customized bolus demonstrated that it is provided good dose escalation and good contact with the irregular surface of the RANDO phantom.

Conclusions: A customized bolus produced using a 3D printer could potentially replace commercially available flat boluses.

Show MeSH