Limits...
Occupational pulmonary aluminosis: a case report.

Smolková P, Nakládalová M, Tichý T, Hampalová M, Kolek V - Ind Health (2014)

Bottom Line: The final diagnosis of pulmonary aluminosis was established after three years of gradual exclusion of other interstitial lung diseases.The diagnosis was supported by the occupational history confirmed by hygiene assessment of the patient's workplace and especially by histological examination with elemental analysis of the lung tissue.The possibility of development of this rare condition should not be underestimated in workers at high-risk jobs.

View Article: PubMed Central - PubMed

Affiliation: Department of Occupational Medicine, Faculty of Medicine and Dentistry, Palacký University Olomouc, Czech Republic.

ABSTRACT
The authors present a case of occupational lung damage from exposure to dust containing aluminium. The first detected objective pathological finding was that of dispersed micronodules in the lungs seen in a chest radiograph. The final diagnosis of pulmonary aluminosis was established after three years of gradual exclusion of other interstitial lung diseases. The diagnosis was supported by the occupational history confirmed by hygiene assessment of the patient's workplace and especially by histological examination with elemental analysis of the lung tissue. The possibility of development of this rare condition should not be underestimated in workers at high-risk jobs.

Show MeSH

Related in: MedlinePlus

Perivascular and peribronchial histiocytic and non-granulomatous infiltrates incollapsed lung tissue in a more detail (haematoxylin and eosin stain, 200 ×magnification).
© Copyright Policy - open-access
Related In: Results  -  Collection

License
getmorefigures.php?uid=PMC4202761&req=5

fig_002: Perivascular and peribronchial histiocytic and non-granulomatous infiltrates incollapsed lung tissue in a more detail (haematoxylin and eosin stain, 200 ×magnification).

Mentions: Therefore, the histological preparation from the original VATS biopsy was reassessed inNovember 2007 at the university hospital. The lung infiltrates were histiocytic andnon-granulomatous, different from well formed granulomas in sarcoidosis. No microcrystallineparticles were found and immunohistochemistry (CD68 positive, S-100 protein and CD1anegative) was not consistent with Langerhans cell histiocytosis. The interstitial fibrosiswas mild (Fig. 2Fig. 2.


Occupational pulmonary aluminosis: a case report.

Smolková P, Nakládalová M, Tichý T, Hampalová M, Kolek V - Ind Health (2014)

Perivascular and peribronchial histiocytic and non-granulomatous infiltrates incollapsed lung tissue in a more detail (haematoxylin and eosin stain, 200 ×magnification).
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4202761&req=5

fig_002: Perivascular and peribronchial histiocytic and non-granulomatous infiltrates incollapsed lung tissue in a more detail (haematoxylin and eosin stain, 200 ×magnification).
Mentions: Therefore, the histological preparation from the original VATS biopsy was reassessed inNovember 2007 at the university hospital. The lung infiltrates were histiocytic andnon-granulomatous, different from well formed granulomas in sarcoidosis. No microcrystallineparticles were found and immunohistochemistry (CD68 positive, S-100 protein and CD1anegative) was not consistent with Langerhans cell histiocytosis. The interstitial fibrosiswas mild (Fig. 2Fig. 2.

Bottom Line: The final diagnosis of pulmonary aluminosis was established after three years of gradual exclusion of other interstitial lung diseases.The diagnosis was supported by the occupational history confirmed by hygiene assessment of the patient's workplace and especially by histological examination with elemental analysis of the lung tissue.The possibility of development of this rare condition should not be underestimated in workers at high-risk jobs.

View Article: PubMed Central - PubMed

Affiliation: Department of Occupational Medicine, Faculty of Medicine and Dentistry, Palacký University Olomouc, Czech Republic.

ABSTRACT
The authors present a case of occupational lung damage from exposure to dust containing aluminium. The first detected objective pathological finding was that of dispersed micronodules in the lungs seen in a chest radiograph. The final diagnosis of pulmonary aluminosis was established after three years of gradual exclusion of other interstitial lung diseases. The diagnosis was supported by the occupational history confirmed by hygiene assessment of the patient's workplace and especially by histological examination with elemental analysis of the lung tissue. The possibility of development of this rare condition should not be underestimated in workers at high-risk jobs.

Show MeSH
Related in: MedlinePlus