Limits...
Gastric adenocarcinoma with thymic metastasis after curative resection: a case report.

Matsunaga T, Saito H, Miyatani K, Takaya S, Fukumoto Y, Osaki T, Ikeguchi M - J Gastric Cancer (2014)

Bottom Line: In contrast, metastasis to the thymus is rare.The patient underwent video-assisted thoracic surgery to remove the tumor.Thymic metastasis was considered likely based on the location of the tumor.

View Article: PubMed Central - PubMed

Affiliation: Division of Surgical Oncology, Department of Surgery, Tottori University School of Medicine, Yonago, Japan.

ABSTRACT
The peritoneum is the most frequent site of recurrence for gastric cancer after gastrectomy, followed by the liver and lymph nodes. In contrast, metastasis to the thymus is rare. Annual surveillance with computed tomography was performed on a 67-year-old man who previously underwent a distal gastrectomy and D2 lymph node dissection for gastric cancer at Tottori University. Five years after the initial operation, an anterior mediastinal tumor was detected by computed tomography. The patient underwent video-assisted thoracic surgery to remove the tumor. Histopathology revealed adenocarcinoma cells similar to those of the gastric cancer resected 5 years previously. Thymic metastasis was considered likely based on the location of the tumor. The recognition that gastric cancer can metastasize to unusual anatomic locations, such as the thymus, can facilitate an accurate, prompt diagnosis and appropriate treatment.

No MeSH data available.


Related in: MedlinePlus

Enhanced computed tomography scan revealed an anterior mediastinal tumor.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
getmorefigures.php?uid=PMC4199889&req=5

Figure 2: Enhanced computed tomography scan revealed an anterior mediastinal tumor.

Mentions: Four years and 8 months after the initial operation, a computed tomography scan from the chest to the pelvis demonstrated a tumor in the anterior mediastinum (Fig. 2). With 18F-fluorodeoxyglucose positron emission tomography computed tomography, a focal hypermetabolic lesion with a maximum standardized uptake value of 3.6 was identified in this lesion (Fig. 3). The patient underwent an anterior mediastinal tumor resection by video-assisted thoracic surgery (Fig. 4); the preoperative diagnosis was thymoma, thymic carcinoma, or malignant lymphoma in the thymus. Histopathology of the tumor revealed adenocarcinoma cells that were similar to those of the gastric cancer resected 5 years previously. Furthermore, immunochemistry indicated that tumor cells were positive for cytokeratin 20 and CDX-2 (C and D) and negative for cytokeratin 7.


Gastric adenocarcinoma with thymic metastasis after curative resection: a case report.

Matsunaga T, Saito H, Miyatani K, Takaya S, Fukumoto Y, Osaki T, Ikeguchi M - J Gastric Cancer (2014)

Enhanced computed tomography scan revealed an anterior mediastinal tumor.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4199889&req=5

Figure 2: Enhanced computed tomography scan revealed an anterior mediastinal tumor.
Mentions: Four years and 8 months after the initial operation, a computed tomography scan from the chest to the pelvis demonstrated a tumor in the anterior mediastinum (Fig. 2). With 18F-fluorodeoxyglucose positron emission tomography computed tomography, a focal hypermetabolic lesion with a maximum standardized uptake value of 3.6 was identified in this lesion (Fig. 3). The patient underwent an anterior mediastinal tumor resection by video-assisted thoracic surgery (Fig. 4); the preoperative diagnosis was thymoma, thymic carcinoma, or malignant lymphoma in the thymus. Histopathology of the tumor revealed adenocarcinoma cells that were similar to those of the gastric cancer resected 5 years previously. Furthermore, immunochemistry indicated that tumor cells were positive for cytokeratin 20 and CDX-2 (C and D) and negative for cytokeratin 7.

Bottom Line: In contrast, metastasis to the thymus is rare.The patient underwent video-assisted thoracic surgery to remove the tumor.Thymic metastasis was considered likely based on the location of the tumor.

View Article: PubMed Central - PubMed

Affiliation: Division of Surgical Oncology, Department of Surgery, Tottori University School of Medicine, Yonago, Japan.

ABSTRACT
The peritoneum is the most frequent site of recurrence for gastric cancer after gastrectomy, followed by the liver and lymph nodes. In contrast, metastasis to the thymus is rare. Annual surveillance with computed tomography was performed on a 67-year-old man who previously underwent a distal gastrectomy and D2 lymph node dissection for gastric cancer at Tottori University. Five years after the initial operation, an anterior mediastinal tumor was detected by computed tomography. The patient underwent video-assisted thoracic surgery to remove the tumor. Histopathology revealed adenocarcinoma cells similar to those of the gastric cancer resected 5 years previously. Thymic metastasis was considered likely based on the location of the tumor. The recognition that gastric cancer can metastasize to unusual anatomic locations, such as the thymus, can facilitate an accurate, prompt diagnosis and appropriate treatment.

No MeSH data available.


Related in: MedlinePlus