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Initial puffing behaviors and subjective responses differ between an electronic nicotine delivery system and traditional cigarettes.

Norton KJ, June KM, O'Connor RJ - Tob Induc Dis (2014)

Bottom Line: Participants used a topography device to record puff volume, duration, flow rate, and inter-puff interval.Analyses revealed significant differences across products in puff count, average volume, total volume and inter-puff interval, with ENDS broadly showing a more intensive smoking pattern.CO boost, after ENDS use, decreased significantly (p < .001), and saliva cotinine significantly dropped between visits 1 and 3 (p < 0.001) after ENDS use relative to after cigarette smoking.

View Article: PubMed Central - HTML - PubMed

Affiliation: Department of Health Behavior, Roswell Park Cancer Institute, Elm and Carlton Streets, 14263 Buffalo, NY, USA.

ABSTRACT

Background: Electronic nicotine delivery systems (ENDS) present an emerging issue for tobacco control and data on product use behaviors are limited.

Methods: Participants (N = 38 enrolled; N = 16 compliant) completed three lab visits over 5 days and were asked to abstain from regular cigarettes for 72 hours in favor of ENDS (Smoke 51 TRIO - 3 piece, First Generation with 11 mg/ml filters). Lab visits included measurement of exhaled carbon monoxide (CO) and salivary cotinine concentration, questionnaire measures of regular cigarette craving after the 72 hour abstinence, and subjective product effects. Participants used a topography device to record puff volume, duration, flow rate, and inter-puff interval.

Results: Analyses revealed significant differences across products in puff count, average volume, total volume and inter-puff interval, with ENDS broadly showing a more intensive smoking pattern. Cigarette craving scores dropped significantly after smoking regular cigarettes, but not ENDS (p = .001), and subjective measures showed ENDS rated less favorably. CO boost, after ENDS use, decreased significantly (p < .001), and saliva cotinine significantly dropped between visits 1 and 3 (p < 0.001) after ENDS use relative to after cigarette smoking. For compliant and non-compliant participants, there was an average 82.0% [V1 - 16.1 cpd; V3 - 2.9 cpd] and average 73.9% [V1 - 20.3 cpd; V3 - 5.3 cpd] reduction in regular cigarette use per day during the ENDS trial period, respectively.

Conclusions: The ENDS were smoked more intensively than own brand cigarettes, but delivered significantly less nicotineand were less satisfying. These findings have implications for the viability of certain ENDS as alternatives to cigarettes.

No MeSH data available.


Related in: MedlinePlus

Mean values for cigarette evaluation scale items after smoking cigarettes and using ENDS.
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Figure 3: Mean values for cigarette evaluation scale items after smoking cigarettes and using ENDS.

Mentions: In the laboratory sessions, the observed drop in both QSU Factor 1 & Factor 2 cigarette craving scores (pre-post smoking, n = 32) was statistically significantly greater when smoking own brand cigarettes (Figure 2), compared to ENDS [product * time F(2,30) = 9.62, p = .001]. Indeed, on neither QSU scale did the initial ENDS trial show a significant reduction after use (p’s > .57). Models including gender and age did not show a substantially different pattern of findingsand interaction terms with product and/or time were not statistically significant.Several measures on the Cigarette Evaluation Scale (CES) showed significant differences between cigarettes and ENDS (Figure 3) (n = 32) including satisfaction [F(1,31) = 20.94, p < .001], taste good [F = 4.54, p = .04], dizziness [F = 28.07, p < .001], feeling more awake [F = 12.40, p = .001], reduced hunger for food [F = 22.51, p < .001], increased nausea [F = 10.92, p = .002], feeling less irritable [F = 13.65, p = .001], and reduced craving to smoke cigarettes [F = 28.79, p < .001]. In each case, cigarettes showed significantly higher scores than ENDS. In a separate model, we examined product by age and product by gender interactions. Only two significant effects emerged – women rated cigarettes and ENDS similarly on enjoyment of airway sensation (3.0 vs. 3.4) while men rated cigarettes more highly (4.1 vs. 2.3) [F (1,29) = 8.33, p = .007]. A similar pattern was seen for women (3.8 vs. 3.7) and men (4.4 vs. 2.6) on the ‘taste good’ measure [F = 5.87, p = .02]. The QSU and CES measures were also taken during Visit 3, but due to the low number of completed and compliant participants, are not reported.


Initial puffing behaviors and subjective responses differ between an electronic nicotine delivery system and traditional cigarettes.

Norton KJ, June KM, O'Connor RJ - Tob Induc Dis (2014)

Mean values for cigarette evaluation scale items after smoking cigarettes and using ENDS.
© Copyright Policy - open-access
Related In: Results  -  Collection

License 1 - License 2
Show All Figures
getmorefigures.php?uid=PMC4199458&req=5

Figure 3: Mean values for cigarette evaluation scale items after smoking cigarettes and using ENDS.
Mentions: In the laboratory sessions, the observed drop in both QSU Factor 1 & Factor 2 cigarette craving scores (pre-post smoking, n = 32) was statistically significantly greater when smoking own brand cigarettes (Figure 2), compared to ENDS [product * time F(2,30) = 9.62, p = .001]. Indeed, on neither QSU scale did the initial ENDS trial show a significant reduction after use (p’s > .57). Models including gender and age did not show a substantially different pattern of findingsand interaction terms with product and/or time were not statistically significant.Several measures on the Cigarette Evaluation Scale (CES) showed significant differences between cigarettes and ENDS (Figure 3) (n = 32) including satisfaction [F(1,31) = 20.94, p < .001], taste good [F = 4.54, p = .04], dizziness [F = 28.07, p < .001], feeling more awake [F = 12.40, p = .001], reduced hunger for food [F = 22.51, p < .001], increased nausea [F = 10.92, p = .002], feeling less irritable [F = 13.65, p = .001], and reduced craving to smoke cigarettes [F = 28.79, p < .001]. In each case, cigarettes showed significantly higher scores than ENDS. In a separate model, we examined product by age and product by gender interactions. Only two significant effects emerged – women rated cigarettes and ENDS similarly on enjoyment of airway sensation (3.0 vs. 3.4) while men rated cigarettes more highly (4.1 vs. 2.3) [F (1,29) = 8.33, p = .007]. A similar pattern was seen for women (3.8 vs. 3.7) and men (4.4 vs. 2.6) on the ‘taste good’ measure [F = 5.87, p = .02]. The QSU and CES measures were also taken during Visit 3, but due to the low number of completed and compliant participants, are not reported.

Bottom Line: Participants used a topography device to record puff volume, duration, flow rate, and inter-puff interval.Analyses revealed significant differences across products in puff count, average volume, total volume and inter-puff interval, with ENDS broadly showing a more intensive smoking pattern.CO boost, after ENDS use, decreased significantly (p < .001), and saliva cotinine significantly dropped between visits 1 and 3 (p < 0.001) after ENDS use relative to after cigarette smoking.

View Article: PubMed Central - HTML - PubMed

Affiliation: Department of Health Behavior, Roswell Park Cancer Institute, Elm and Carlton Streets, 14263 Buffalo, NY, USA.

ABSTRACT

Background: Electronic nicotine delivery systems (ENDS) present an emerging issue for tobacco control and data on product use behaviors are limited.

Methods: Participants (N = 38 enrolled; N = 16 compliant) completed three lab visits over 5 days and were asked to abstain from regular cigarettes for 72 hours in favor of ENDS (Smoke 51 TRIO - 3 piece, First Generation with 11 mg/ml filters). Lab visits included measurement of exhaled carbon monoxide (CO) and salivary cotinine concentration, questionnaire measures of regular cigarette craving after the 72 hour abstinence, and subjective product effects. Participants used a topography device to record puff volume, duration, flow rate, and inter-puff interval.

Results: Analyses revealed significant differences across products in puff count, average volume, total volume and inter-puff interval, with ENDS broadly showing a more intensive smoking pattern. Cigarette craving scores dropped significantly after smoking regular cigarettes, but not ENDS (p = .001), and subjective measures showed ENDS rated less favorably. CO boost, after ENDS use, decreased significantly (p < .001), and saliva cotinine significantly dropped between visits 1 and 3 (p < 0.001) after ENDS use relative to after cigarette smoking. For compliant and non-compliant participants, there was an average 82.0% [V1 - 16.1 cpd; V3 - 2.9 cpd] and average 73.9% [V1 - 20.3 cpd; V3 - 5.3 cpd] reduction in regular cigarette use per day during the ENDS trial period, respectively.

Conclusions: The ENDS were smoked more intensively than own brand cigarettes, but delivered significantly less nicotineand were less satisfying. These findings have implications for the viability of certain ENDS as alternatives to cigarettes.

No MeSH data available.


Related in: MedlinePlus