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Cutaneous leiomyosarcoma - Case report.

Ciurea ME, Georgescu CV, Radu CC, Georgescu CC, Stoica LE - J Med Life (2014)

Bottom Line: Primary tumor excision with wide oncological safety margins is considered, when suitable case, the most appropriate method.Other therapeutic methods, such as radio- or chemotherapy are described as without significant benefits.We recommend long-term follow-up of patients to capture a subsequent malignant disease progression.

View Article: PubMed Central - PubMed

Affiliation: Department of Plastic and Reconstructive Surgery, Craiova University of Medicine and Pharmacy.

ABSTRACT
Cutaneous leiomyosarcoma (CLM) is a very rare smooth muscle tumor arising from the dermis or subcutaneous tissue in the skin. Superficial leiomyosarcoma originates in the superficial dermis or subcutaneous tissue and represents about 3% of the soft tissue sarcomas. CLM presents in persons of all ages but with a peak between 60-70 years old. It may also occur anywhere on the body; the existing cases reported it on the face and trunk. The clinic of leiomyosarcoma consists in a firm dermal nodule, which can be painful, pruritic or paresthestic. The tumor is of 1-3 cm in diameter and can often be seen as a solitary formation. We report one case of a cutaneous leiomyosarcoma arising in the chest region of a 79- year-old male. Leiomyosarcoma is a rare entity whose clinical presentation may appear nonspecific, making diagnosis difficult. Primary tumor excision with wide oncological safety margins is considered, when suitable case, the most appropriate method. Other therapeutic methods, such as radio- or chemotherapy are described as without significant benefits. Despite the claims of radical surgical treatment, due to recurrence rates, the prognosis remains poor. We recommend long-term follow-up of patients to capture a subsequent malignant disease progression.

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Clinical aspect: well-demarcated, irregular, firm erythematous nodule on chest region
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Figure 1: Clinical aspect: well-demarcated, irregular, firm erythematous nodule on chest region

Mentions: A 79-year-old male presented to our department with a painless nodule on chest region, which had been progressively increasing in size for 10 years. Physical examination revealed an irregular, firm, tender exophytic swelling, measuring 4 cm diameter at the anterior trunk (Fig. 1). There were no signs of infection and the overlying skin was normal. The remainder of the clinical examination was normal. Lymph nodes were not palpable. His past history was significant of a local trauma.


Cutaneous leiomyosarcoma - Case report.

Ciurea ME, Georgescu CV, Radu CC, Georgescu CC, Stoica LE - J Med Life (2014)

Clinical aspect: well-demarcated, irregular, firm erythematous nodule on chest region
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4197510&req=5

Figure 1: Clinical aspect: well-demarcated, irregular, firm erythematous nodule on chest region
Mentions: A 79-year-old male presented to our department with a painless nodule on chest region, which had been progressively increasing in size for 10 years. Physical examination revealed an irregular, firm, tender exophytic swelling, measuring 4 cm diameter at the anterior trunk (Fig. 1). There were no signs of infection and the overlying skin was normal. The remainder of the clinical examination was normal. Lymph nodes were not palpable. His past history was significant of a local trauma.

Bottom Line: Primary tumor excision with wide oncological safety margins is considered, when suitable case, the most appropriate method.Other therapeutic methods, such as radio- or chemotherapy are described as without significant benefits.We recommend long-term follow-up of patients to capture a subsequent malignant disease progression.

View Article: PubMed Central - PubMed

Affiliation: Department of Plastic and Reconstructive Surgery, Craiova University of Medicine and Pharmacy.

ABSTRACT
Cutaneous leiomyosarcoma (CLM) is a very rare smooth muscle tumor arising from the dermis or subcutaneous tissue in the skin. Superficial leiomyosarcoma originates in the superficial dermis or subcutaneous tissue and represents about 3% of the soft tissue sarcomas. CLM presents in persons of all ages but with a peak between 60-70 years old. It may also occur anywhere on the body; the existing cases reported it on the face and trunk. The clinic of leiomyosarcoma consists in a firm dermal nodule, which can be painful, pruritic or paresthestic. The tumor is of 1-3 cm in diameter and can often be seen as a solitary formation. We report one case of a cutaneous leiomyosarcoma arising in the chest region of a 79- year-old male. Leiomyosarcoma is a rare entity whose clinical presentation may appear nonspecific, making diagnosis difficult. Primary tumor excision with wide oncological safety margins is considered, when suitable case, the most appropriate method. Other therapeutic methods, such as radio- or chemotherapy are described as without significant benefits. Despite the claims of radical surgical treatment, due to recurrence rates, the prognosis remains poor. We recommend long-term follow-up of patients to capture a subsequent malignant disease progression.

Show MeSH
Related in: MedlinePlus