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Comparison of clinical outcomes of Chinese men and women after coronary stenting for coronary artery disease: a multi-center retrospective analysis of 4,334 patients.

Shrestha R, Xu J, Xie D, Liu Z, Xu T, Ye F, Din S, Qian X, Yang S, Liu Y, Li F, Zhang A, Chen S - J Biomed Res (2013)

Bottom Line: We compared these groups with respect to the primary outcomes of MI and secondary outcomes including a composite of major adverse cardiac events (MACE) including cardiac death, MI, target lesion revascularization, target vessel revascularization (TVR), stent thrombosis (ST), definite ST and probable ST at one-year follow-up.Chinese male and female patients showed a significant difference on MACEs.However, there was no significant difference with respect to MI between these groups.

View Article: PubMed Central - PubMed

Affiliation: Department of Cardiology, Nanjing Medical University, Nanjing, Jiangsu 210029, China.

ABSTRACT
The outcome differences between Chinese male and female patients within one-year follow-up after percutaneous coronary intervention (PCI) with stent remain unclear. The present study was aimed to compare clinical outcomes in such two populations. From May 1999 to December 2009, 4,334 patients with acute myocardial infarction (MI), unstable angina, stable angina, or silent ischemia, who underwent PCI, were registered at our centers. Among these, 3,089 were men and 1,245 were women. We compared these groups with respect to the primary outcomes of MI and secondary outcomes including a composite of major adverse cardiac events (MACE) including cardiac death, MI, target lesion revascularization, target vessel revascularization (TVR), stent thrombosis (ST), definite ST and probable ST at one-year follow-up. Chinese male patients had a higher MACE rate (13% vs. 10.7%, P  =  0.039), mainly led by TVR (9.09% vs. 6.98%, P = 0.024) at one year, which was significantly different than female patients. Chinese male and female patients showed a significant difference on MACEs. However, there was no significant difference with respect to MI between these groups.

No MeSH data available.


Related in: MedlinePlus

One-year myocardial infarction free survival functions. Kaplan-Meier free survival curves for one-year MI between male and female patients undergoing percutaneous coronary intervention.
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f01: One-year myocardial infarction free survival functions. Kaplan-Meier free survival curves for one-year MI between male and female patients undergoing percutaneous coronary intervention.

Mentions: Kaplan-Meier analysis is shown in Fig. 1 for MI patients at the one-year follow-up after PCI by using Log rank test. It was determined that there was no significant difference between male and female patients (P  =  0.144). However, there was a significant difference between the two groups with respect to one-year MACE during the follow-up period (P  =  0.041).


Comparison of clinical outcomes of Chinese men and women after coronary stenting for coronary artery disease: a multi-center retrospective analysis of 4,334 patients.

Shrestha R, Xu J, Xie D, Liu Z, Xu T, Ye F, Din S, Qian X, Yang S, Liu Y, Li F, Zhang A, Chen S - J Biomed Res (2013)

One-year myocardial infarction free survival functions. Kaplan-Meier free survival curves for one-year MI between male and female patients undergoing percutaneous coronary intervention.
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC4197387&req=5

f01: One-year myocardial infarction free survival functions. Kaplan-Meier free survival curves for one-year MI between male and female patients undergoing percutaneous coronary intervention.
Mentions: Kaplan-Meier analysis is shown in Fig. 1 for MI patients at the one-year follow-up after PCI by using Log rank test. It was determined that there was no significant difference between male and female patients (P  =  0.144). However, there was a significant difference between the two groups with respect to one-year MACE during the follow-up period (P  =  0.041).

Bottom Line: We compared these groups with respect to the primary outcomes of MI and secondary outcomes including a composite of major adverse cardiac events (MACE) including cardiac death, MI, target lesion revascularization, target vessel revascularization (TVR), stent thrombosis (ST), definite ST and probable ST at one-year follow-up.Chinese male and female patients showed a significant difference on MACEs.However, there was no significant difference with respect to MI between these groups.

View Article: PubMed Central - PubMed

Affiliation: Department of Cardiology, Nanjing Medical University, Nanjing, Jiangsu 210029, China.

ABSTRACT
The outcome differences between Chinese male and female patients within one-year follow-up after percutaneous coronary intervention (PCI) with stent remain unclear. The present study was aimed to compare clinical outcomes in such two populations. From May 1999 to December 2009, 4,334 patients with acute myocardial infarction (MI), unstable angina, stable angina, or silent ischemia, who underwent PCI, were registered at our centers. Among these, 3,089 were men and 1,245 were women. We compared these groups with respect to the primary outcomes of MI and secondary outcomes including a composite of major adverse cardiac events (MACE) including cardiac death, MI, target lesion revascularization, target vessel revascularization (TVR), stent thrombosis (ST), definite ST and probable ST at one-year follow-up. Chinese male patients had a higher MACE rate (13% vs. 10.7%, P  =  0.039), mainly led by TVR (9.09% vs. 6.98%, P = 0.024) at one year, which was significantly different than female patients. Chinese male and female patients showed a significant difference on MACEs. However, there was no significant difference with respect to MI between these groups.

No MeSH data available.


Related in: MedlinePlus