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Nigerian Population Research on Environment, Gene and Health (NIPREGH) - objectives and protocol.

Odili AN, Ogedengbe JO, Nwegbu M, Anumah FO, Asala S, Staessen JA - J Biomed Res (2014)

Bottom Line: The mean (SD) of office and home blood pressures were 113.0 (15.2) mm Hg systolic, 73.5 (12.5) mm Hg diastolic and 117.3 (15.0) mm Hg systolic, and 76.0 (9.6) mm Hg diastolic, respectively.Forty-three (26.8%) participants were hypertensive and 8 (5.0%) were diabetic.In addition to having the unique potential of recruiting a cohort that is a true representative of the entire Nigerian population, NIPREGH is feasible and the objectives realisable.

View Article: PubMed Central - PubMed

Affiliation: Department of Internal Medicine, Faculty of Clinical Sciences, College of Health Sciences, University of Abuja, Abuja, Nigeria. ; Studies Coordinating Centre, Division of Hypertension and Cardiovascular Rehabilitation, Department of Cardiovascular Diseases, University of Leuven, Leuven, Belgium.

ABSTRACT
Sub-Saharan Africa is currently undergoing an epidemiological transition from a disease burden largely attributable to communicable diseases to that resulting from a combination of both communicable and chronic non-communicable diseases. Data on chronic disease incidence, lifestyle, environmental and genetic risk factors are sparse in this region. This report aimed at providing relevant information in respect to risk factors that increase blood pressure and lead to development of intermediate cardiovascular phenotypes. We presented the rationale, objectives and key methodological features of the Nigerian Population Research on Environment, Gene and Health (NIPREGH) study. The challenges encountered in carrying out population study in this part of the world and the approaches at surmounting them were also presented. The preliminary data as at 20 November 2013 showed that out of the 205 individuals invited starting from early April 2013, 160 (72 women) consented and were enrolled; giving a response rate of 78%. Participants' age ranged from 18 to 80 years, with a mean (SD) of 39.8 (12.4) years and they were of 34 different ethnic groups spread over 24 states out of the 36 states that constitute Nigeria. The mean (SD) of office and home blood pressures were 113.0 (15.2) mm Hg systolic, 73.5 (12.5) mm Hg diastolic and 117.3 (15.0) mm Hg systolic, and 76.0 (9.6) mm Hg diastolic, respectively. Forty-three (26.8%) participants were hypertensive and 8 (5.0%) were diabetic. In addition to having the unique potential of recruiting a cohort that is a true representative of the entire Nigerian population, NIPREGH is feasible and the objectives realisable.

No MeSH data available.


Related in: MedlinePlus

Age distribution of recruited participants (hatched bars) in comparison with the country age distribution (solid bars) as reported in the 2006 census figures.
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Related In: Results  -  Collection


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f02: Age distribution of recruited participants (hatched bars) in comparison with the country age distribution (solid bars) as reported in the 2006 census figures.

Mentions: The state of origin of the 160 participants, 58% of whom are women; spanned across 24 out of 36 states of Nigeria (Fig. 1) The age distribution as shown in Fig. 2 typifies the age structure of Nigeria with age ranging from 18 to 80 years and mean (SD), 39.8 (12.4) years. 66 (41.3%) participants consume significant alcohol while 4 (2.5%, all men) smoked cigarette. 43 (26.8%) and 8 (5.0%) were hypertensive and diabetic respectively. Women were significantly more obese (P < 0.01) than men, mean (SD) BMI; 27.9 (5.3) vs. 25.7 (4.2) kg/m2. Other aspects of the baseline characteristics are shown in Table 3. The office blood pressure averaged 113 mmHg systolic and 73.5 mmHg diastolic, while the corresponding self-measured home values were 117.3 mmHg, and 76.0 mmHg, respectively (Table 4).


Nigerian Population Research on Environment, Gene and Health (NIPREGH) - objectives and protocol.

Odili AN, Ogedengbe JO, Nwegbu M, Anumah FO, Asala S, Staessen JA - J Biomed Res (2014)

Age distribution of recruited participants (hatched bars) in comparison with the country age distribution (solid bars) as reported in the 2006 census figures.
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC4197386&req=5

f02: Age distribution of recruited participants (hatched bars) in comparison with the country age distribution (solid bars) as reported in the 2006 census figures.
Mentions: The state of origin of the 160 participants, 58% of whom are women; spanned across 24 out of 36 states of Nigeria (Fig. 1) The age distribution as shown in Fig. 2 typifies the age structure of Nigeria with age ranging from 18 to 80 years and mean (SD), 39.8 (12.4) years. 66 (41.3%) participants consume significant alcohol while 4 (2.5%, all men) smoked cigarette. 43 (26.8%) and 8 (5.0%) were hypertensive and diabetic respectively. Women were significantly more obese (P < 0.01) than men, mean (SD) BMI; 27.9 (5.3) vs. 25.7 (4.2) kg/m2. Other aspects of the baseline characteristics are shown in Table 3. The office blood pressure averaged 113 mmHg systolic and 73.5 mmHg diastolic, while the corresponding self-measured home values were 117.3 mmHg, and 76.0 mmHg, respectively (Table 4).

Bottom Line: The mean (SD) of office and home blood pressures were 113.0 (15.2) mm Hg systolic, 73.5 (12.5) mm Hg diastolic and 117.3 (15.0) mm Hg systolic, and 76.0 (9.6) mm Hg diastolic, respectively.Forty-three (26.8%) participants were hypertensive and 8 (5.0%) were diabetic.In addition to having the unique potential of recruiting a cohort that is a true representative of the entire Nigerian population, NIPREGH is feasible and the objectives realisable.

View Article: PubMed Central - PubMed

Affiliation: Department of Internal Medicine, Faculty of Clinical Sciences, College of Health Sciences, University of Abuja, Abuja, Nigeria. ; Studies Coordinating Centre, Division of Hypertension and Cardiovascular Rehabilitation, Department of Cardiovascular Diseases, University of Leuven, Leuven, Belgium.

ABSTRACT
Sub-Saharan Africa is currently undergoing an epidemiological transition from a disease burden largely attributable to communicable diseases to that resulting from a combination of both communicable and chronic non-communicable diseases. Data on chronic disease incidence, lifestyle, environmental and genetic risk factors are sparse in this region. This report aimed at providing relevant information in respect to risk factors that increase blood pressure and lead to development of intermediate cardiovascular phenotypes. We presented the rationale, objectives and key methodological features of the Nigerian Population Research on Environment, Gene and Health (NIPREGH) study. The challenges encountered in carrying out population study in this part of the world and the approaches at surmounting them were also presented. The preliminary data as at 20 November 2013 showed that out of the 205 individuals invited starting from early April 2013, 160 (72 women) consented and were enrolled; giving a response rate of 78%. Participants' age ranged from 18 to 80 years, with a mean (SD) of 39.8 (12.4) years and they were of 34 different ethnic groups spread over 24 states out of the 36 states that constitute Nigeria. The mean (SD) of office and home blood pressures were 113.0 (15.2) mm Hg systolic, 73.5 (12.5) mm Hg diastolic and 117.3 (15.0) mm Hg systolic, and 76.0 (9.6) mm Hg diastolic, respectively. Forty-three (26.8%) participants were hypertensive and 8 (5.0%) were diabetic. In addition to having the unique potential of recruiting a cohort that is a true representative of the entire Nigerian population, NIPREGH is feasible and the objectives realisable.

No MeSH data available.


Related in: MedlinePlus