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Outbreaks of Ebola virus disease in Africa: the beginnings of a tragic saga.

Chippaux JP - J Venom Anim Toxins Incl Trop Dis (2014)

Bottom Line: The tremendous outbreak of Ebola virus disease occurring in West Africa since the end of 2013 surprises by its remoteness from previous epidemics and dramatic extent.It provides an update on research on the ecology of Ebola viruses, modes of contamination and human transmission of the disease that are mainly linked to close contact with an infected animal or a patient suffering from the disease.The recommendations to contain the epidemic and challenges to achieve it are reminded.

View Article: PubMed Central - PubMed

Affiliation: UMR 216, Mother and Child Facing Tropical Diseases, Institut de Recherche pour le Développement (IRD), Cotonou, Bénin ; Sorbonne Paris Cité, Faculté de Pharmacie, Université Paris Descartes, Paris, France.

ABSTRACT
The tremendous outbreak of Ebola virus disease occurring in West Africa since the end of 2013 surprises by its remoteness from previous epidemics and dramatic extent. This review aims to describe the 27 manifestations of Ebola virus that arose after its discovery in 1976. It provides an update on research on the ecology of Ebola viruses, modes of contamination and human transmission of the disease that are mainly linked to close contact with an infected animal or a patient suffering from the disease. The recommendations to contain the epidemic and challenges to achieve it are reminded.

No MeSH data available.


Related in: MedlinePlus

Alert delay and duration of the African Ebola outbreaks.
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Fig6: Alert delay and duration of the African Ebola outbreaks.

Mentions: Beyond the diversity of African outbreaks, particularly regarding the incidence and duration of the epidemics (Table 5), we can notice that most of them presented only one source of infection accounting for the spread of the virus. As a result, it can be assumed that either the opportunities for human contact with the virus are rare, or the risk of contamination is limited. The period between the index case and the alert averages about two months. In addition, an equivalent period occurs between the alert and the last confirmed case (Figure 6).Table 5


Outbreaks of Ebola virus disease in Africa: the beginnings of a tragic saga.

Chippaux JP - J Venom Anim Toxins Incl Trop Dis (2014)

Alert delay and duration of the African Ebola outbreaks.
© Copyright Policy - open-access
Related In: Results  -  Collection

License 1 - License 2
Show All Figures
getmorefigures.php?uid=PMC4197285&req=5

Fig6: Alert delay and duration of the African Ebola outbreaks.
Mentions: Beyond the diversity of African outbreaks, particularly regarding the incidence and duration of the epidemics (Table 5), we can notice that most of them presented only one source of infection accounting for the spread of the virus. As a result, it can be assumed that either the opportunities for human contact with the virus are rare, or the risk of contamination is limited. The period between the index case and the alert averages about two months. In addition, an equivalent period occurs between the alert and the last confirmed case (Figure 6).Table 5

Bottom Line: The tremendous outbreak of Ebola virus disease occurring in West Africa since the end of 2013 surprises by its remoteness from previous epidemics and dramatic extent.It provides an update on research on the ecology of Ebola viruses, modes of contamination and human transmission of the disease that are mainly linked to close contact with an infected animal or a patient suffering from the disease.The recommendations to contain the epidemic and challenges to achieve it are reminded.

View Article: PubMed Central - PubMed

Affiliation: UMR 216, Mother and Child Facing Tropical Diseases, Institut de Recherche pour le Développement (IRD), Cotonou, Bénin ; Sorbonne Paris Cité, Faculté de Pharmacie, Université Paris Descartes, Paris, France.

ABSTRACT
The tremendous outbreak of Ebola virus disease occurring in West Africa since the end of 2013 surprises by its remoteness from previous epidemics and dramatic extent. This review aims to describe the 27 manifestations of Ebola virus that arose after its discovery in 1976. It provides an update on research on the ecology of Ebola viruses, modes of contamination and human transmission of the disease that are mainly linked to close contact with an infected animal or a patient suffering from the disease. The recommendations to contain the epidemic and challenges to achieve it are reminded.

No MeSH data available.


Related in: MedlinePlus