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Disentangling the attention network test: behavioral, event related potentials, and neural source analyses.

Galvao-Carmona A, González-Rosa JJ, Hidalgo-Muñoz AR, Páramo D, Benítez ML, Izquierdo G, Vázquez-Marrufo M - Front Hum Neurosci (2014)

Bottom Line: The study of the attentional system remains a challenge for current neuroscience.In particular, it is highly relevant that several interpretations about attentional impairment have arisen from these calculations in diverse pathologies.The ANT is useful as a paradigm to study specific attentional mechanisms and their interactions.

View Article: PubMed Central - PubMed

Affiliation: Psychophysiology Unit (Lab B508), Department of Experimental Psychology, Faculty of Psychology, University of Seville Seville, Spain.

ABSTRACT

Background: The study of the attentional system remains a challenge for current neuroscience. The "Attention Network Test" (ANT) was designed to study simultaneously three different attentional networks (alerting, orienting, and executive) based in subtraction of different experimental conditions. However, some studies recommend caution with these calculations due to the interactions between the attentional networks. In particular, it is highly relevant that several interpretations about attentional impairment have arisen from these calculations in diverse pathologies. Event related potentials (ERPs) and neural source analysis can be applied to disentangle the relationships between these attentional networks not specifically shown by behavioral measures.

Results: This study shows that there is a basic level of alerting (tonic alerting) in the no cue (NC) condition, represented by a slow negative trend in the ERP trace prior to the onset of the target stimuli. A progressive increase in the CNV amplitude related to the amount of information provided by the cue conditions is also shown. Neural source analysis reveals specific modulations of the CNV related to a task-related expectancy presented in the NC condition; a late modulation triggered by the central cue (CC) condition and probably representing a generic motor preparation; and an early and late modulation for spatial cue (SC) condition suggesting specific motor and sensory preactivation. Finally, the first component in the information processing of the target stimuli modulated by the interaction between orienting network and the executive system can be represented by N1.

Conclusions: The ANT is useful as a paradigm to study specific attentional mechanisms and their interactions. However, calculation of network effects is based in subtractions with non-comparable experimental conditions, as evidenced by the present data, which can induce misinterpretations in the study of the attentional capacity in human subjects.

No MeSH data available.


Related in: MedlinePlus

P1 and N1 modulations in every cue condition at the PO5 and PO6 electrodes and topographical maps. Abbreviations: ms, milliseconds; μV, microvolts.
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Figure 6: P1 and N1 modulations in every cue condition at the PO5 and PO6 electrodes and topographical maps. Abbreviations: ms, milliseconds; μV, microvolts.

Mentions: PO5 and PO6 electrodes gave the maximum amplitude value for the P1 and N1 components for all cue × congruence conditions. Table 4 summarizes latency and amplitude values of the P1 and N1 component analyzed for each condition. RM-ANOVA showed no effect in the P1 latency for any factor. Concerning the amplitude of the P1 component (see Table 4), significant interactions of Cue × Anteroposterior location factors [F(10, 240) = 6.7; p < 0.001] and Cue × Medial-Lateral Position factors [F(12, 288) = 3.296; p < 0.001] were found. Post-hoc t-test indicated that the SC condition has the highest amplitude for the P1 compared to the CC and NC conditions in the parieto-occipital electrodes (p < 0.001 for PO5 and PO6 electrodes) (see Figure 6). NC and CC conditions were not significantly different with these electrodes (p > 0.05).


Disentangling the attention network test: behavioral, event related potentials, and neural source analyses.

Galvao-Carmona A, González-Rosa JJ, Hidalgo-Muñoz AR, Páramo D, Benítez ML, Izquierdo G, Vázquez-Marrufo M - Front Hum Neurosci (2014)

P1 and N1 modulations in every cue condition at the PO5 and PO6 electrodes and topographical maps. Abbreviations: ms, milliseconds; μV, microvolts.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4195286&req=5

Figure 6: P1 and N1 modulations in every cue condition at the PO5 and PO6 electrodes and topographical maps. Abbreviations: ms, milliseconds; μV, microvolts.
Mentions: PO5 and PO6 electrodes gave the maximum amplitude value for the P1 and N1 components for all cue × congruence conditions. Table 4 summarizes latency and amplitude values of the P1 and N1 component analyzed for each condition. RM-ANOVA showed no effect in the P1 latency for any factor. Concerning the amplitude of the P1 component (see Table 4), significant interactions of Cue × Anteroposterior location factors [F(10, 240) = 6.7; p < 0.001] and Cue × Medial-Lateral Position factors [F(12, 288) = 3.296; p < 0.001] were found. Post-hoc t-test indicated that the SC condition has the highest amplitude for the P1 compared to the CC and NC conditions in the parieto-occipital electrodes (p < 0.001 for PO5 and PO6 electrodes) (see Figure 6). NC and CC conditions were not significantly different with these electrodes (p > 0.05).

Bottom Line: The study of the attentional system remains a challenge for current neuroscience.In particular, it is highly relevant that several interpretations about attentional impairment have arisen from these calculations in diverse pathologies.The ANT is useful as a paradigm to study specific attentional mechanisms and their interactions.

View Article: PubMed Central - PubMed

Affiliation: Psychophysiology Unit (Lab B508), Department of Experimental Psychology, Faculty of Psychology, University of Seville Seville, Spain.

ABSTRACT

Background: The study of the attentional system remains a challenge for current neuroscience. The "Attention Network Test" (ANT) was designed to study simultaneously three different attentional networks (alerting, orienting, and executive) based in subtraction of different experimental conditions. However, some studies recommend caution with these calculations due to the interactions between the attentional networks. In particular, it is highly relevant that several interpretations about attentional impairment have arisen from these calculations in diverse pathologies. Event related potentials (ERPs) and neural source analysis can be applied to disentangle the relationships between these attentional networks not specifically shown by behavioral measures.

Results: This study shows that there is a basic level of alerting (tonic alerting) in the no cue (NC) condition, represented by a slow negative trend in the ERP trace prior to the onset of the target stimuli. A progressive increase in the CNV amplitude related to the amount of information provided by the cue conditions is also shown. Neural source analysis reveals specific modulations of the CNV related to a task-related expectancy presented in the NC condition; a late modulation triggered by the central cue (CC) condition and probably representing a generic motor preparation; and an early and late modulation for spatial cue (SC) condition suggesting specific motor and sensory preactivation. Finally, the first component in the information processing of the target stimuli modulated by the interaction between orienting network and the executive system can be represented by N1.

Conclusions: The ANT is useful as a paradigm to study specific attentional mechanisms and their interactions. However, calculation of network effects is based in subtractions with non-comparable experimental conditions, as evidenced by the present data, which can induce misinterpretations in the study of the attentional capacity in human subjects.

No MeSH data available.


Related in: MedlinePlus