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Incidence and outcome of acute lung injury and acute respiratory distress syndrome in the surgical intensive care unit.

Singh G, Gladdy G, Chandy TT, Sen N - Indian J Crit Care Med (2014)

Bottom Line: The ventilatory parameters and chest radiographs were recorded every 24 h.The P/F ratio, PEEP and Lung Injury Score were calculated each day until the day of discharge from the Intensive Care Unit or for the first 7 days of admission, whichever was shorter.Those who develop ARDS had higher APACHE II scores, lower pH and higher PaCO2 at admission compared with those who developed ALI or no lung injury.

View Article: PubMed Central - PubMed

Affiliation: Department of Anaesthesia, Christian Medical College and Hospital, Vellore, Tamil Nadu, India.

ABSTRACT

Introduction: To determine the incidence and mortality of acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) in a cohort of patients with risk factors admitted to the Surgical Intensive Care Unit (SICU).

Materials and methods: A prospective observational inception cohort study with no intervention was conducted over 12 months. All patients with at least one known risk factor for ALI/ARDS admitted to the SICU were included in the study. The APACHE II severity of disease classification system scoring was performed within 1 h of admission. The ventilatory parameters and chest radiographs were recorded every 24 h. The P/F ratio, PEEP and Lung Injury Score were calculated each day until the day of discharge from the Intensive Care Unit or for the first 7 days of admission, whichever was shorter.

Results: The incidence of ARDS among those who were mechanically ventilated was 11.4%. Sepsis was the most common (34.6%) etiology. Among those with risk factors, the incidence of ARDS was 30% and that of ALI was 32.7%. The mortality in those with ARDS was 41.8%. Those who develop ARDS had higher APACHE II scores, lower pH and higher PaCO2 at admission compared with those who developed ALI or no lung injury.

Conclusion: The incidence and mortality of ARDS was similar to other studies. Identifying those with risk factors for ARDS or mortality will enable appropriate interventional measures.

No MeSH data available.


Related in: MedlinePlus

Pattern of radiological injury among survivors and non-survivors of acute respiratory distress syndrome
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Related In: Results  -  Collection

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Figure 2: Pattern of radiological injury among survivors and non-survivors of acute respiratory distress syndrome


Incidence and outcome of acute lung injury and acute respiratory distress syndrome in the surgical intensive care unit.

Singh G, Gladdy G, Chandy TT, Sen N - Indian J Crit Care Med (2014)

Pattern of radiological injury among survivors and non-survivors of acute respiratory distress syndrome
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4195196&req=5

Figure 2: Pattern of radiological injury among survivors and non-survivors of acute respiratory distress syndrome
Bottom Line: The ventilatory parameters and chest radiographs were recorded every 24 h.The P/F ratio, PEEP and Lung Injury Score were calculated each day until the day of discharge from the Intensive Care Unit or for the first 7 days of admission, whichever was shorter.Those who develop ARDS had higher APACHE II scores, lower pH and higher PaCO2 at admission compared with those who developed ALI or no lung injury.

View Article: PubMed Central - PubMed

Affiliation: Department of Anaesthesia, Christian Medical College and Hospital, Vellore, Tamil Nadu, India.

ABSTRACT

Introduction: To determine the incidence and mortality of acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) in a cohort of patients with risk factors admitted to the Surgical Intensive Care Unit (SICU).

Materials and methods: A prospective observational inception cohort study with no intervention was conducted over 12 months. All patients with at least one known risk factor for ALI/ARDS admitted to the SICU were included in the study. The APACHE II severity of disease classification system scoring was performed within 1 h of admission. The ventilatory parameters and chest radiographs were recorded every 24 h. The P/F ratio, PEEP and Lung Injury Score were calculated each day until the day of discharge from the Intensive Care Unit or for the first 7 days of admission, whichever was shorter.

Results: The incidence of ARDS among those who were mechanically ventilated was 11.4%. Sepsis was the most common (34.6%) etiology. Among those with risk factors, the incidence of ARDS was 30% and that of ALI was 32.7%. The mortality in those with ARDS was 41.8%. Those who develop ARDS had higher APACHE II scores, lower pH and higher PaCO2 at admission compared with those who developed ALI or no lung injury.

Conclusion: The incidence and mortality of ARDS was similar to other studies. Identifying those with risk factors for ARDS or mortality will enable appropriate interventional measures.

No MeSH data available.


Related in: MedlinePlus