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Image findings of monomorphic non-hogdkin lymphoproliferative disorder in a post renal transplant patient diagnosed with fluorine-18 fluorodeoxyglucose-positron emission tomography/computed tomography.

Kamaleshwaran KK, Rajasekar T, Shibu D, Radhakrishnan EK, Shinto AS - Indian J Nucl Med (2014)

Bottom Line: Post-transplant lymphoproliferative disorder (PTLD) is a heterogeneous group of lymphoid proliferations caused by immunosuppression after solid organ or bone marrow transplantation.PTLD is categorized by early lesion, polymorphic PTLD and monomorphic PTLD.Whole body FDG- ET/CT demonstrated uptake in right external iliac and inguinal lymph nodes.

View Article: PubMed Central - PubMed

Affiliation: Department of Nuclear Medicine, PET/CT and Radionuclide therapy, Comprehensive Cancer Care Centre, Kovai Medical Centre and Hospital Limited, Coimbatore, Tamil Nadu, India.

ABSTRACT
Post-transplant lymphoproliferative disorder (PTLD) is a heterogeneous group of lymphoid proliferations caused by immunosuppression after solid organ or bone marrow transplantation. PTLD is categorized by early lesion, polymorphic PTLD and monomorphic PTLD. Fluorine-18 fluorodeoxyglucose-positron emission tomography/computed tomography (F-18 FDG-PET/CT) scans have clinical significance in the evaluation of PTLD following renal transplantation. We report imaging findings of a monomorphic non-Hodgkin lymphoma, post renal transplant seen on FDG PET/CT in a 32-year-old lactating woman. Whole body FDG- ET/CT demonstrated uptake in right external iliac and inguinal lymph nodes.

No MeSH data available.


Related in: MedlinePlus

Whole body fluorodeoxyglucose-positron emission tomography/computed tomography (PET/CT) maximum intensity projection image (a), axial fused PET/CT showed an intense uptake in the right external iliac lymphnodes (b), right breast parenchyma uptake due to lactation (c) and transplant kidney in right iliac fossa (d) noted
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Figure 1: Whole body fluorodeoxyglucose-positron emission tomography/computed tomography (PET/CT) maximum intensity projection image (a), axial fused PET/CT showed an intense uptake in the right external iliac lymphnodes (b), right breast parenchyma uptake due to lactation (c) and transplant kidney in right iliac fossa (d) noted

Mentions: This was a case report of a 32-year-old female patient who had immunoglobulin A nephropathy underwent renal transplant 6 years before and was on immunosuppressants. She is postpartum 6 months and breast feeding, presented with swelling in the right inguinal region. She underwent an excision biopsy of the right inguinal node, which showed diffuse large B cell lymphoma. As a part of evaluation, she was subjected to whole body PET/CT, which showed increased uptake in multiple nodes in right external iliac and inguinal region [Figure 1a and b], also right breast parenchyma uptake [Figure 1c] and transplant kidney noted in right iliac fossa [Figure 1d]. As PET/CT scan confirmed involvement of multiple nodes, patient underwent chemotherapy and asked to stop breast feeding.


Image findings of monomorphic non-hogdkin lymphoproliferative disorder in a post renal transplant patient diagnosed with fluorine-18 fluorodeoxyglucose-positron emission tomography/computed tomography.

Kamaleshwaran KK, Rajasekar T, Shibu D, Radhakrishnan EK, Shinto AS - Indian J Nucl Med (2014)

Whole body fluorodeoxyglucose-positron emission tomography/computed tomography (PET/CT) maximum intensity projection image (a), axial fused PET/CT showed an intense uptake in the right external iliac lymphnodes (b), right breast parenchyma uptake due to lactation (c) and transplant kidney in right iliac fossa (d) noted
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4157200&req=5

Figure 1: Whole body fluorodeoxyglucose-positron emission tomography/computed tomography (PET/CT) maximum intensity projection image (a), axial fused PET/CT showed an intense uptake in the right external iliac lymphnodes (b), right breast parenchyma uptake due to lactation (c) and transplant kidney in right iliac fossa (d) noted
Mentions: This was a case report of a 32-year-old female patient who had immunoglobulin A nephropathy underwent renal transplant 6 years before and was on immunosuppressants. She is postpartum 6 months and breast feeding, presented with swelling in the right inguinal region. She underwent an excision biopsy of the right inguinal node, which showed diffuse large B cell lymphoma. As a part of evaluation, she was subjected to whole body PET/CT, which showed increased uptake in multiple nodes in right external iliac and inguinal region [Figure 1a and b], also right breast parenchyma uptake [Figure 1c] and transplant kidney noted in right iliac fossa [Figure 1d]. As PET/CT scan confirmed involvement of multiple nodes, patient underwent chemotherapy and asked to stop breast feeding.

Bottom Line: Post-transplant lymphoproliferative disorder (PTLD) is a heterogeneous group of lymphoid proliferations caused by immunosuppression after solid organ or bone marrow transplantation.PTLD is categorized by early lesion, polymorphic PTLD and monomorphic PTLD.Whole body FDG- ET/CT demonstrated uptake in right external iliac and inguinal lymph nodes.

View Article: PubMed Central - PubMed

Affiliation: Department of Nuclear Medicine, PET/CT and Radionuclide therapy, Comprehensive Cancer Care Centre, Kovai Medical Centre and Hospital Limited, Coimbatore, Tamil Nadu, India.

ABSTRACT
Post-transplant lymphoproliferative disorder (PTLD) is a heterogeneous group of lymphoid proliferations caused by immunosuppression after solid organ or bone marrow transplantation. PTLD is categorized by early lesion, polymorphic PTLD and monomorphic PTLD. Fluorine-18 fluorodeoxyglucose-positron emission tomography/computed tomography (F-18 FDG-PET/CT) scans have clinical significance in the evaluation of PTLD following renal transplantation. We report imaging findings of a monomorphic non-Hodgkin lymphoma, post renal transplant seen on FDG PET/CT in a 32-year-old lactating woman. Whole body FDG- ET/CT demonstrated uptake in right external iliac and inguinal lymph nodes.

No MeSH data available.


Related in: MedlinePlus