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Asymptomatic cauda equina metastasis in a patient with nasopharyngeal carcinoma: Detection by (18)F-FDG PET/CT.

Karunanithi S, Jain S, Sharma P, Bal C, Kumar R - Indian J Nucl Med (2014)

Bottom Line: The central nervous system metastasis from nasopharyngeal carcinoma (NPC) is an extremely rare occurrence, although direct intracranial invasion is not infrequent in patients with NPC.Herein we report a case of a 62-year-old male with NPC, in whom the asymptomatic cauda equina metastasis was detected on staging (18)F-Fluordeoxyglucose positron emission tomography-computed tomography (F-FDG PET/CT).By demonstrating distant metastasis to cauda equina, (18)F-FDG PET/CT detection helped in change of management in this patient.

View Article: PubMed Central - PubMed

Affiliation: Department of Nuclear Medicine, All India Institute of Medical Sciences, New Delhi, India.

ABSTRACT
The central nervous system metastasis from nasopharyngeal carcinoma (NPC) is an extremely rare occurrence, although direct intracranial invasion is not infrequent in patients with NPC. Herein we report a case of a 62-year-old male with NPC, in whom the asymptomatic cauda equina metastasis was detected on staging (18)F-Fluordeoxyglucose positron emission tomography-computed tomography (F-FDG PET/CT). By demonstrating distant metastasis to cauda equina, (18)F-FDG PET/CT detection helped in change of management in this patient.

No MeSH data available.


Related in: MedlinePlus

18F-FDG PET/CT study for staging. PET/CT revealed 18F-FDG avid primary malignant disease involving the roof and posterior wall of nasopharynx and bilateral fossa of rossenmuller (a and b; broken arrow), with metastases to bilateral cervical and left supraclavicular lymph nodes (a and c; arrows). A discrete 18F-FDG avid nodular lesion was noted in the cauda equina region at the level of L4-L5 vertebrae (a,d-g; bold arrow)
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Figure 1: 18F-FDG PET/CT study for staging. PET/CT revealed 18F-FDG avid primary malignant disease involving the roof and posterior wall of nasopharynx and bilateral fossa of rossenmuller (a and b; broken arrow), with metastases to bilateral cervical and left supraclavicular lymph nodes (a and c; arrows). A discrete 18F-FDG avid nodular lesion was noted in the cauda equina region at the level of L4-L5 vertebrae (a,d-g; bold arrow)

Mentions: PET/CT revealed 18F-FDG avid primary malignant disease involving the roof and posterior wall of nasopharynx and bilateral fossa of rossenmuller, with metastases to bilateral cervical and left supraclavicular lymph nodes. Interestingly, a discrete 18F-FDG avid (SUVmax-8.6) nodular lesion was noted in the cauda equina region at the level of L4-L5 vertebrae, which was highly suggestive of metastasis [Figure 1]. This lesion was later confirmed to be metastatic at contrast-enhanced magnetic resonance imaging (MRI) and the patient was referred for regional radiotherapy. The patient then underwent chemotherapy and regional radiotherapy to cauda equina lesion.


Asymptomatic cauda equina metastasis in a patient with nasopharyngeal carcinoma: Detection by (18)F-FDG PET/CT.

Karunanithi S, Jain S, Sharma P, Bal C, Kumar R - Indian J Nucl Med (2014)

18F-FDG PET/CT study for staging. PET/CT revealed 18F-FDG avid primary malignant disease involving the roof and posterior wall of nasopharynx and bilateral fossa of rossenmuller (a and b; broken arrow), with metastases to bilateral cervical and left supraclavicular lymph nodes (a and c; arrows). A discrete 18F-FDG avid nodular lesion was noted in the cauda equina region at the level of L4-L5 vertebrae (a,d-g; bold arrow)
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4157196&req=5

Figure 1: 18F-FDG PET/CT study for staging. PET/CT revealed 18F-FDG avid primary malignant disease involving the roof and posterior wall of nasopharynx and bilateral fossa of rossenmuller (a and b; broken arrow), with metastases to bilateral cervical and left supraclavicular lymph nodes (a and c; arrows). A discrete 18F-FDG avid nodular lesion was noted in the cauda equina region at the level of L4-L5 vertebrae (a,d-g; bold arrow)
Mentions: PET/CT revealed 18F-FDG avid primary malignant disease involving the roof and posterior wall of nasopharynx and bilateral fossa of rossenmuller, with metastases to bilateral cervical and left supraclavicular lymph nodes. Interestingly, a discrete 18F-FDG avid (SUVmax-8.6) nodular lesion was noted in the cauda equina region at the level of L4-L5 vertebrae, which was highly suggestive of metastasis [Figure 1]. This lesion was later confirmed to be metastatic at contrast-enhanced magnetic resonance imaging (MRI) and the patient was referred for regional radiotherapy. The patient then underwent chemotherapy and regional radiotherapy to cauda equina lesion.

Bottom Line: The central nervous system metastasis from nasopharyngeal carcinoma (NPC) is an extremely rare occurrence, although direct intracranial invasion is not infrequent in patients with NPC.Herein we report a case of a 62-year-old male with NPC, in whom the asymptomatic cauda equina metastasis was detected on staging (18)F-Fluordeoxyglucose positron emission tomography-computed tomography (F-FDG PET/CT).By demonstrating distant metastasis to cauda equina, (18)F-FDG PET/CT detection helped in change of management in this patient.

View Article: PubMed Central - PubMed

Affiliation: Department of Nuclear Medicine, All India Institute of Medical Sciences, New Delhi, India.

ABSTRACT
The central nervous system metastasis from nasopharyngeal carcinoma (NPC) is an extremely rare occurrence, although direct intracranial invasion is not infrequent in patients with NPC. Herein we report a case of a 62-year-old male with NPC, in whom the asymptomatic cauda equina metastasis was detected on staging (18)F-Fluordeoxyglucose positron emission tomography-computed tomography (F-FDG PET/CT). By demonstrating distant metastasis to cauda equina, (18)F-FDG PET/CT detection helped in change of management in this patient.

No MeSH data available.


Related in: MedlinePlus