Limits...
Remineralization and repair of enamel surface by biomimetic Zn-carbonate hydroxyapatite containing toothpaste: a comparative in vivo study.

Lelli M, Putignano A, Marchetti M, Foltran I, Mangani F, Procaccini M, Roveri N, Orsini G - Front Physiol (2014)

Bottom Line: Teeth were processed for morphological and chemical-physic superficial characterizations by means of Scanning Electronic Microscopy with Elementary analysis, X-Ray Diffraction analysis and Infrared analysis.On the other hand, the use of both a nitrate potassium/sodium fluoride and non-specified fluoride toothpastes did not appreciably change the enamel surface.In conclusion, this study demonstrates that the toothpaste containing Zn-CHA nanostructured microcrystals, differently from nitrate potassium/sodium fluoride and non-specified fluoride toothpastes, may promote enamel superficial repair by means of the formation of a protective biomimetic CHA coating.

View Article: PubMed Central - PubMed

Affiliation: Department of Chemistry "G. Ciamician," Alma Mater Studiorum, University of Bologna Bologna, Italy.

ABSTRACT
Consumption of acidic foods and drinks and other factors that cause enamel wear are responsible for the daily enamel loss and degradation. Use of some toothpastes that have been showed to possess different properties of remineralisation and/or repair of the enamel surface may help to protect tooth enamel. The aim of this study was to evaluate whether the use of toothpaste containing Zn-carbonate hydroxyapatite (CHA) nanostructured microcrystals may exert remineralization/repair effects of the enamel surface. Two groups of patients, aged between 18 and 75 years, used a Zn-CHA nanocrystals-based toothpaste (experimental group) and a potassium nitrate/sodium fluoride toothpaste (active control group) for 8 weeks. At the end of this period, extractions were performed in five subjects per study group. Negative controls consisted of two subjects treated with non-specified fluoride toothpaste. Teeth were processed for morphological and chemical-physic superficial characterizations by means of Scanning Electronic Microscopy with Elementary analysis, X-Ray Diffraction analysis and Infrared analysis. In this study, the use of a Zn-CHA nanocrystals toothpaste led to a remineralization/repair of the enamel surface, by deposition of a hydroxyapatite-rich coating. On the other hand, the use of both a nitrate potassium/sodium fluoride and non-specified fluoride toothpastes did not appreciably change the enamel surface. In conclusion, this study demonstrates that the toothpaste containing Zn-CHA nanostructured microcrystals, differently from nitrate potassium/sodium fluoride and non-specified fluoride toothpastes, may promote enamel superficial repair by means of the formation of a protective biomimetic CHA coating.

No MeSH data available.


Related in: MedlinePlus

DRX pattern of the enamel after the in vivo treatment using the following. (A) synthetic biomimetic CHA nanostructured microclusters, (B) Zn-CHA toothpaste, (C) KNO3/NaF toothpaste, (D) Fluoride toothpaste.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
getmorefigures.php?uid=PMC4155874&req=5

Figure 7: DRX pattern of the enamel after the in vivo treatment using the following. (A) synthetic biomimetic CHA nanostructured microclusters, (B) Zn-CHA toothpaste, (C) KNO3/NaF toothpaste, (D) Fluoride toothpaste.

Mentions: Figure 7A shows the broadened X-Ray diffraction maxima of the synthetic biomimetic CHA microclusters of the Zn-CHA experimental toothpaste. This XRD pattern can be compared with the ones obtained from enamel slabs of teeth treated using Zn-CHA toothpaste, KNO3/NaF toothpaste and fluoride toothpaste, reported in Figures 7B–D, respectively. The XRD pattern obtained from enamel surfaces treated using Zn-CHA toothpaste (Figure 7B) is similar to the one obtained from Zn-CHA nanostructured microclusters (Figure 7A), thus revealing its deposition on the enamel surface.


Remineralization and repair of enamel surface by biomimetic Zn-carbonate hydroxyapatite containing toothpaste: a comparative in vivo study.

Lelli M, Putignano A, Marchetti M, Foltran I, Mangani F, Procaccini M, Roveri N, Orsini G - Front Physiol (2014)

DRX pattern of the enamel after the in vivo treatment using the following. (A) synthetic biomimetic CHA nanostructured microclusters, (B) Zn-CHA toothpaste, (C) KNO3/NaF toothpaste, (D) Fluoride toothpaste.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4155874&req=5

Figure 7: DRX pattern of the enamel after the in vivo treatment using the following. (A) synthetic biomimetic CHA nanostructured microclusters, (B) Zn-CHA toothpaste, (C) KNO3/NaF toothpaste, (D) Fluoride toothpaste.
Mentions: Figure 7A shows the broadened X-Ray diffraction maxima of the synthetic biomimetic CHA microclusters of the Zn-CHA experimental toothpaste. This XRD pattern can be compared with the ones obtained from enamel slabs of teeth treated using Zn-CHA toothpaste, KNO3/NaF toothpaste and fluoride toothpaste, reported in Figures 7B–D, respectively. The XRD pattern obtained from enamel surfaces treated using Zn-CHA toothpaste (Figure 7B) is similar to the one obtained from Zn-CHA nanostructured microclusters (Figure 7A), thus revealing its deposition on the enamel surface.

Bottom Line: Teeth were processed for morphological and chemical-physic superficial characterizations by means of Scanning Electronic Microscopy with Elementary analysis, X-Ray Diffraction analysis and Infrared analysis.On the other hand, the use of both a nitrate potassium/sodium fluoride and non-specified fluoride toothpastes did not appreciably change the enamel surface.In conclusion, this study demonstrates that the toothpaste containing Zn-CHA nanostructured microcrystals, differently from nitrate potassium/sodium fluoride and non-specified fluoride toothpastes, may promote enamel superficial repair by means of the formation of a protective biomimetic CHA coating.

View Article: PubMed Central - PubMed

Affiliation: Department of Chemistry "G. Ciamician," Alma Mater Studiorum, University of Bologna Bologna, Italy.

ABSTRACT
Consumption of acidic foods and drinks and other factors that cause enamel wear are responsible for the daily enamel loss and degradation. Use of some toothpastes that have been showed to possess different properties of remineralisation and/or repair of the enamel surface may help to protect tooth enamel. The aim of this study was to evaluate whether the use of toothpaste containing Zn-carbonate hydroxyapatite (CHA) nanostructured microcrystals may exert remineralization/repair effects of the enamel surface. Two groups of patients, aged between 18 and 75 years, used a Zn-CHA nanocrystals-based toothpaste (experimental group) and a potassium nitrate/sodium fluoride toothpaste (active control group) for 8 weeks. At the end of this period, extractions were performed in five subjects per study group. Negative controls consisted of two subjects treated with non-specified fluoride toothpaste. Teeth were processed for morphological and chemical-physic superficial characterizations by means of Scanning Electronic Microscopy with Elementary analysis, X-Ray Diffraction analysis and Infrared analysis. In this study, the use of a Zn-CHA nanocrystals toothpaste led to a remineralization/repair of the enamel surface, by deposition of a hydroxyapatite-rich coating. On the other hand, the use of both a nitrate potassium/sodium fluoride and non-specified fluoride toothpastes did not appreciably change the enamel surface. In conclusion, this study demonstrates that the toothpaste containing Zn-CHA nanostructured microcrystals, differently from nitrate potassium/sodium fluoride and non-specified fluoride toothpastes, may promote enamel superficial repair by means of the formation of a protective biomimetic CHA coating.

No MeSH data available.


Related in: MedlinePlus