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De qi, a threshold of the stimulus intensity, elicits the specific response of acupoints and intrinsic change of human brain to acupuncture.

Tian DS, Xiong J, Pan Q, Liu F, Wang L, Xu SB, Huang GY, Wang W - Evid Based Complement Alternat Med (2014)

Bottom Line: Results.Furthermore, acupuncture treatment induced fMRI signal increase/decrease in different brain regions although no significant change in electroencephalography.Interpretation.

View Article: PubMed Central - PubMed

Affiliation: Department of Neurology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.

ABSTRACT
Objectives.  De qi is the subjective constellation of sensations perceived by the acupuncturists and patients as described in several literatures, but the absence of quantitative evaluation methods in de qi restricts the use of acupuncture treatment widely in the world. In the present study, we tried to investigate the intrinsic property of de qi is and how evaluate it quantitatively. Methods. 30 healthy adult volunteers were determined to investigate intrinsic changes in the human body after acupuncture with de qi. Results. Acupuncture treatment with de qi apparently increased acupoint blood flow, tissue displacement, and the amplitude of myoelectricity after de qi on acupoints. Furthermore, acupuncture treatment induced fMRI signal increase/decrease in different brain regions although no significant change in electroencephalography. Interpretation. The intrinsic change of the subjects representing the specific response of acupoints and human brain to acupuncture indicated that de qi might be evaluated quantitatively by those above aspects, which facilitated the confirmation in validity and propagation of this treatment modality widely in the world.

No MeSH data available.


Related in: MedlinePlus

Acupuncture manipulation paradigm. Manual acupuncture was administered to LI4 and ST36 on the right. The subject's sensitivity to needling was pretested and adjusted to tolerance prior to scanning. After remaining in place for 30 s (R1), the needle was rotated forward and backward with stimulation for 30 s at the rate of 60 times per minute with an amplitude of approximately 180° in each direction (S1). After a rest period of 30 s (R2), needle manipulation was repeated in the same manner (S2). The needle was withdrawn after completion of 5 cycles of R-S acupuncture.
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fig2: Acupuncture manipulation paradigm. Manual acupuncture was administered to LI4 and ST36 on the right. The subject's sensitivity to needling was pretested and adjusted to tolerance prior to scanning. After remaining in place for 30 s (R1), the needle was rotated forward and backward with stimulation for 30 s at the rate of 60 times per minute with an amplitude of approximately 180° in each direction (S1). After a rest period of 30 s (R2), needle manipulation was repeated in the same manner (S2). The needle was withdrawn after completion of 5 cycles of R-S acupuncture.

Mentions: Disposable sterile stainless steel needles (KINGLI Medical Appliance Co., Ltd., Wuxi, China) of 0.22 mm in diameter and 40 mm in length were used. The needle was inserted vertically to a depth of 2-3 cm. The sensitivity of the subject to needle manipulation was tested and adjusted to tolerance prior to procedure, aiming to elicit de qi sensation without noxious pain. In the event of a sharp painful sensation, the needle position should be readjusted and the pain would disappear within a few seconds. During the acupuncture procedure, the subjects were questioned about the sensations that they had felt and whether the de qi sensations (aching, pressure, soreness, heaviness, fullness, warmth, cooling, numbness, tingling, and dull pain), sharp pain or any other sensations, occurred. The stimulation paradigm is depicted in Figure 2. The needle was kept in place for 2 min prior to needle manipulation and then was rotated approximately 180° in each direction with even motion at the rate of one cycle per second, which is a technique used in clinical practice. The two stimulation blocks, for example, S1 and S2, were separated by an interval of 30 s as a break period with needle remaining in place.


De qi, a threshold of the stimulus intensity, elicits the specific response of acupoints and intrinsic change of human brain to acupuncture.

Tian DS, Xiong J, Pan Q, Liu F, Wang L, Xu SB, Huang GY, Wang W - Evid Based Complement Alternat Med (2014)

Acupuncture manipulation paradigm. Manual acupuncture was administered to LI4 and ST36 on the right. The subject's sensitivity to needling was pretested and adjusted to tolerance prior to scanning. After remaining in place for 30 s (R1), the needle was rotated forward and backward with stimulation for 30 s at the rate of 60 times per minute with an amplitude of approximately 180° in each direction (S1). After a rest period of 30 s (R2), needle manipulation was repeated in the same manner (S2). The needle was withdrawn after completion of 5 cycles of R-S acupuncture.
© Copyright Policy - open-access
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC4151069&req=5

fig2: Acupuncture manipulation paradigm. Manual acupuncture was administered to LI4 and ST36 on the right. The subject's sensitivity to needling was pretested and adjusted to tolerance prior to scanning. After remaining in place for 30 s (R1), the needle was rotated forward and backward with stimulation for 30 s at the rate of 60 times per minute with an amplitude of approximately 180° in each direction (S1). After a rest period of 30 s (R2), needle manipulation was repeated in the same manner (S2). The needle was withdrawn after completion of 5 cycles of R-S acupuncture.
Mentions: Disposable sterile stainless steel needles (KINGLI Medical Appliance Co., Ltd., Wuxi, China) of 0.22 mm in diameter and 40 mm in length were used. The needle was inserted vertically to a depth of 2-3 cm. The sensitivity of the subject to needle manipulation was tested and adjusted to tolerance prior to procedure, aiming to elicit de qi sensation without noxious pain. In the event of a sharp painful sensation, the needle position should be readjusted and the pain would disappear within a few seconds. During the acupuncture procedure, the subjects were questioned about the sensations that they had felt and whether the de qi sensations (aching, pressure, soreness, heaviness, fullness, warmth, cooling, numbness, tingling, and dull pain), sharp pain or any other sensations, occurred. The stimulation paradigm is depicted in Figure 2. The needle was kept in place for 2 min prior to needle manipulation and then was rotated approximately 180° in each direction with even motion at the rate of one cycle per second, which is a technique used in clinical practice. The two stimulation blocks, for example, S1 and S2, were separated by an interval of 30 s as a break period with needle remaining in place.

Bottom Line: Results.Furthermore, acupuncture treatment induced fMRI signal increase/decrease in different brain regions although no significant change in electroencephalography.Interpretation.

View Article: PubMed Central - PubMed

Affiliation: Department of Neurology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.

ABSTRACT
Objectives.  De qi is the subjective constellation of sensations perceived by the acupuncturists and patients as described in several literatures, but the absence of quantitative evaluation methods in de qi restricts the use of acupuncture treatment widely in the world. In the present study, we tried to investigate the intrinsic property of de qi is and how evaluate it quantitatively. Methods. 30 healthy adult volunteers were determined to investigate intrinsic changes in the human body after acupuncture with de qi. Results. Acupuncture treatment with de qi apparently increased acupoint blood flow, tissue displacement, and the amplitude of myoelectricity after de qi on acupoints. Furthermore, acupuncture treatment induced fMRI signal increase/decrease in different brain regions although no significant change in electroencephalography. Interpretation. The intrinsic change of the subjects representing the specific response of acupoints and human brain to acupuncture indicated that de qi might be evaluated quantitatively by those above aspects, which facilitated the confirmation in validity and propagation of this treatment modality widely in the world.

No MeSH data available.


Related in: MedlinePlus