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Plexiform unicystic ameloblastoma: a rare variant of ameloblastoma.

Deore SS, Dandekar RC, Mahajan AM, Patil R, Prakash N - Case Rep Dent (2014)

Bottom Line: Because of unilocular presentation, it is commonly misdiagnosed as an odontogenic cyst.This paper aims to provide an insight into this biologically distinct entity.A literature review on the topic has been added along with a case report highlighting the approach of diagnosis and management of such ameloblastomas.

View Article: PubMed Central - PubMed

Affiliation: Department of Oral Pathology & Microbiology, Jawahar Medical Foundation's Annasaheb Chudaman Patil Memorial Dental College & Hospital, Sakri Road, Morane, Dhule, Maharashtra 424001, India.

ABSTRACT
The term plexiform unicystic ameloblastoma refers to a pattern of epithelial proliferation that has been described in cystic cavity. Because of unilocular presentation, it is commonly misdiagnosed as an odontogenic cyst. However, they may often behave clinically as biologically aggressive tumors. These tumors show high incidence of cortical perforation, tooth resorption and a high rate of recurrence after simple enucleation. This paper aims to provide an insight into this biologically distinct entity. A literature review on the topic has been added along with a case report highlighting the approach of diagnosis and management of such ameloblastomas.

No MeSH data available.


Related in: MedlinePlus

H & E stained section showing ameloblastic cystic epithelium showing intraluminal proliferation in the form of plexiform pattern ((a) H & E stain; 100x and (b) H & E Stain; 40x).
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fig9: H & E stained section showing ameloblastic cystic epithelium showing intraluminal proliferation in the form of plexiform pattern ((a) H & E stain; 100x and (b) H & E Stain; 40x).

Mentions: We received a segmental resected specimen involving condyle, coronoid process, upto ascending ramus, which showed perforation in the anterior border of ascending ramus. Histopathological examination of the excisional biopsy specimen showed lesional tissue that consisted of a cystic cavity lined by odontogenic epithelium and connective tissue capsule. The epithelium showed cuboidal or columnar basal cells with hyperchromatic nuclei, nuclear palisading with polarization, cytoplasmic vacuolization with intercellular spacing, and subepithelial hyalinization and superficial layer showing stellate reticulum-like cells. There was also proliferation of these cells in cystic lumen in a plexiform pattern. The cells are arranged in interconnecting strands and cords with peripheral palisaded layer and central stellate reticulum-like cells (Figure 9). Tissue material resembling an odontogenic keratocyst lining was not observed, even with serial sections of tissue. So possibility of ameloblastic transformation of odontogenic keratocyst was also excluded.


Plexiform unicystic ameloblastoma: a rare variant of ameloblastoma.

Deore SS, Dandekar RC, Mahajan AM, Patil R, Prakash N - Case Rep Dent (2014)

H & E stained section showing ameloblastic cystic epithelium showing intraluminal proliferation in the form of plexiform pattern ((a) H & E stain; 100x and (b) H & E Stain; 40x).
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4150428&req=5

fig9: H & E stained section showing ameloblastic cystic epithelium showing intraluminal proliferation in the form of plexiform pattern ((a) H & E stain; 100x and (b) H & E Stain; 40x).
Mentions: We received a segmental resected specimen involving condyle, coronoid process, upto ascending ramus, which showed perforation in the anterior border of ascending ramus. Histopathological examination of the excisional biopsy specimen showed lesional tissue that consisted of a cystic cavity lined by odontogenic epithelium and connective tissue capsule. The epithelium showed cuboidal or columnar basal cells with hyperchromatic nuclei, nuclear palisading with polarization, cytoplasmic vacuolization with intercellular spacing, and subepithelial hyalinization and superficial layer showing stellate reticulum-like cells. There was also proliferation of these cells in cystic lumen in a plexiform pattern. The cells are arranged in interconnecting strands and cords with peripheral palisaded layer and central stellate reticulum-like cells (Figure 9). Tissue material resembling an odontogenic keratocyst lining was not observed, even with serial sections of tissue. So possibility of ameloblastic transformation of odontogenic keratocyst was also excluded.

Bottom Line: Because of unilocular presentation, it is commonly misdiagnosed as an odontogenic cyst.This paper aims to provide an insight into this biologically distinct entity.A literature review on the topic has been added along with a case report highlighting the approach of diagnosis and management of such ameloblastomas.

View Article: PubMed Central - PubMed

Affiliation: Department of Oral Pathology & Microbiology, Jawahar Medical Foundation's Annasaheb Chudaman Patil Memorial Dental College & Hospital, Sakri Road, Morane, Dhule, Maharashtra 424001, India.

ABSTRACT
The term plexiform unicystic ameloblastoma refers to a pattern of epithelial proliferation that has been described in cystic cavity. Because of unilocular presentation, it is commonly misdiagnosed as an odontogenic cyst. However, they may often behave clinically as biologically aggressive tumors. These tumors show high incidence of cortical perforation, tooth resorption and a high rate of recurrence after simple enucleation. This paper aims to provide an insight into this biologically distinct entity. A literature review on the topic has been added along with a case report highlighting the approach of diagnosis and management of such ameloblastomas.

No MeSH data available.


Related in: MedlinePlus