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Protonation equilibria of biologically active ligands in mixed aqueous organic solvents.

El-Sherif AA, Shoukry MM, Abd Elkarim AT, Barakat MH - Bioinorg Chem Appl (2014)

Bottom Line: The review is mainly concerned with the protonation equilibria of biologically active ligands like amino acids, peptides, DNA constituents, and amino acid esters in nonaqueous media.Equilibrium concentrations of proton-ligand formation as a function of pH were investigated.Also, thermodynamics associated with protonation equilibria were also discussed.

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Affiliation: Chemistry Department, Faculty of Science, Cairo University, Giza, Egypt ; Department of Chemistry, Faculty of Arts and Science, Northern Border University, Rafha, Saudi Arabia.

ABSTRACT
The review is mainly concerned with the protonation equilibria of biologically active ligands like amino acids, peptides, DNA constituents, and amino acid esters in nonaqueous media. Equilibrium concentrations of proton-ligand formation as a function of pH were investigated. Also, thermodynamics associated with protonation equilibria were also discussed.

No MeSH data available.


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Mentions: Two protonation equilibria were found for all glycine-dipeptides (Figure 4) mentioned in Table 5.


Protonation equilibria of biologically active ligands in mixed aqueous organic solvents.

El-Sherif AA, Shoukry MM, Abd Elkarim AT, Barakat MH - Bioinorg Chem Appl (2014)

© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4150405&req=5

Mentions: Two protonation equilibria were found for all glycine-dipeptides (Figure 4) mentioned in Table 5.

Bottom Line: The review is mainly concerned with the protonation equilibria of biologically active ligands like amino acids, peptides, DNA constituents, and amino acid esters in nonaqueous media.Equilibrium concentrations of proton-ligand formation as a function of pH were investigated.Also, thermodynamics associated with protonation equilibria were also discussed.

View Article: PubMed Central - PubMed

Affiliation: Chemistry Department, Faculty of Science, Cairo University, Giza, Egypt ; Department of Chemistry, Faculty of Arts and Science, Northern Border University, Rafha, Saudi Arabia.

ABSTRACT
The review is mainly concerned with the protonation equilibria of biologically active ligands like amino acids, peptides, DNA constituents, and amino acid esters in nonaqueous media. Equilibrium concentrations of proton-ligand formation as a function of pH were investigated. Also, thermodynamics associated with protonation equilibria were also discussed.

No MeSH data available.