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Evaluation of vaginal cytology in female sex-workers: A study in a tertiary hospital of eastern India.

Mondal SK, Basak B, Roy DN, Mandal PK, Sinha S - J Cytol (2014)

Bottom Line: Incidence of HSIL was very high in FSWs.Close follow-up and histologic examinations are necessary to avoid unnecessary spread of the neoplastic disease and untimely death of the patients.Awareness about diseases in FSWs and diagnostic utility of Pap test are also a must.

View Article: PubMed Central - PubMed

Affiliation: Department of Pathology, Medical College, Kolkata, West Bengal, India.

ABSTRACT

Background: Papanicolaou (Pap) test is an important and easy diagnostic tool to detect any abnormalities on vaginal cytology. Pap test is routinely done in women of reproductive age group in many countries.

Aim: The aim of this study was to detect spectrum of abnormalities in female sex workers (FSWs) on vaginal cytology.

Materials and methods: A total of 60 cases were included over a period of 1 year (July, 2011-June, 2012). The age range of the patients was 14-61 years. Pap stained slides were evaluated by two consultant cytopathologists and reported as normal smear, inflammatory smear, specific infection, low grade squamous intraepithelial lesion (LSIL), high grade squamous intraepithelial lesion (HSIL), atypical squamous cell of undetermined significance (ASCUS), squamous cell carcinoma (SCC) and atypical glandular cell of undetermined significance (AGUS).

Results: Most of the smears were abnormal accounting for 86.7% of total cases (52/60). Incidence of HSIL was very high in FSWs. Out of 60 cases, 8 normal smears (13.3%), 12 inflammatory smears (20%), 3 cases of infections (5%), 9 cases of LSIL (15%), 23 cases of HSIL (38.3%), 2 cases (3.3%) each of ASCUS and SCC and 1 case (1.3%) AGUS were encountered.

Conclusions: Close follow-up and histologic examinations are necessary to avoid unnecessary spread of the neoplastic disease and untimely death of the patients. Awareness about diseases in FSWs and diagnostic utility of Pap test are also a must.

No MeSH data available.


Related in: MedlinePlus

(a) Photomicrograph showing inflammatory smear (Pap, ×100). (b) Photomicrograph showing low grade squamous intraepithelial lesion with koilocytic change in some of the cells (Pap, ×400). The cells have mild increase in nucleocytoplasmic ratio and hyperchromatic nuclei
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Figure 1: (a) Photomicrograph showing inflammatory smear (Pap, ×100). (b) Photomicrograph showing low grade squamous intraepithelial lesion with koilocytic change in some of the cells (Pap, ×400). The cells have mild increase in nucleocytoplasmic ratio and hyperchromatic nuclei

Mentions: A total of 60 cases were included in this study during the time period of 1 year. The age range of the patients was 14-61 years. Total 16 (26.67%) out of 60 patients were below the age of 30 years and 44 (73.33%) were above 30 years of age. Out of 60 smears, 52 (86.67%) smears showed pathologic findings [Figures 1 and 2]. Premalignant lesions were found in 37 (61.67%, n = 60) smears of which ASCUS was 2 (3.3%), LSIL-9 (15%), HSIL-23 (38.3%), SCC-2 (3.3%) and AGUS-1 (1.7%) [Table 1]. Among the patients of below 30 years (n = 16), premalignant lesions were found in 8 (50%) patients of which ASCUS was 1 (6.3%), LSIL-5 (31.2%) and HSIL-2 (12.5%) [Table 1]. Total inflammatory smears were 36 (60%, n = 60), of which 12 smears showed nonspecific inflammation, 10 smears were associated with HSIL, 8 smears were associated with LSIL, 2 smears were associated with ASCUS, 1 smear was associated with AGUS and 3 smears were associated with specific infections. One smear showed features of both human papilloma virus (HPV) and herpes simplex virus (HSV) infections, 2 smears were associated with features of both HPV and Trichomonas vaginalis infections.


Evaluation of vaginal cytology in female sex-workers: A study in a tertiary hospital of eastern India.

Mondal SK, Basak B, Roy DN, Mandal PK, Sinha S - J Cytol (2014)

(a) Photomicrograph showing inflammatory smear (Pap, ×100). (b) Photomicrograph showing low grade squamous intraepithelial lesion with koilocytic change in some of the cells (Pap, ×400). The cells have mild increase in nucleocytoplasmic ratio and hyperchromatic nuclei
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4150348&req=5

Figure 1: (a) Photomicrograph showing inflammatory smear (Pap, ×100). (b) Photomicrograph showing low grade squamous intraepithelial lesion with koilocytic change in some of the cells (Pap, ×400). The cells have mild increase in nucleocytoplasmic ratio and hyperchromatic nuclei
Mentions: A total of 60 cases were included in this study during the time period of 1 year. The age range of the patients was 14-61 years. Total 16 (26.67%) out of 60 patients were below the age of 30 years and 44 (73.33%) were above 30 years of age. Out of 60 smears, 52 (86.67%) smears showed pathologic findings [Figures 1 and 2]. Premalignant lesions were found in 37 (61.67%, n = 60) smears of which ASCUS was 2 (3.3%), LSIL-9 (15%), HSIL-23 (38.3%), SCC-2 (3.3%) and AGUS-1 (1.7%) [Table 1]. Among the patients of below 30 years (n = 16), premalignant lesions were found in 8 (50%) patients of which ASCUS was 1 (6.3%), LSIL-5 (31.2%) and HSIL-2 (12.5%) [Table 1]. Total inflammatory smears were 36 (60%, n = 60), of which 12 smears showed nonspecific inflammation, 10 smears were associated with HSIL, 8 smears were associated with LSIL, 2 smears were associated with ASCUS, 1 smear was associated with AGUS and 3 smears were associated with specific infections. One smear showed features of both human papilloma virus (HPV) and herpes simplex virus (HSV) infections, 2 smears were associated with features of both HPV and Trichomonas vaginalis infections.

Bottom Line: Incidence of HSIL was very high in FSWs.Close follow-up and histologic examinations are necessary to avoid unnecessary spread of the neoplastic disease and untimely death of the patients.Awareness about diseases in FSWs and diagnostic utility of Pap test are also a must.

View Article: PubMed Central - PubMed

Affiliation: Department of Pathology, Medical College, Kolkata, West Bengal, India.

ABSTRACT

Background: Papanicolaou (Pap) test is an important and easy diagnostic tool to detect any abnormalities on vaginal cytology. Pap test is routinely done in women of reproductive age group in many countries.

Aim: The aim of this study was to detect spectrum of abnormalities in female sex workers (FSWs) on vaginal cytology.

Materials and methods: A total of 60 cases were included over a period of 1 year (July, 2011-June, 2012). The age range of the patients was 14-61 years. Pap stained slides were evaluated by two consultant cytopathologists and reported as normal smear, inflammatory smear, specific infection, low grade squamous intraepithelial lesion (LSIL), high grade squamous intraepithelial lesion (HSIL), atypical squamous cell of undetermined significance (ASCUS), squamous cell carcinoma (SCC) and atypical glandular cell of undetermined significance (AGUS).

Results: Most of the smears were abnormal accounting for 86.7% of total cases (52/60). Incidence of HSIL was very high in FSWs. Out of 60 cases, 8 normal smears (13.3%), 12 inflammatory smears (20%), 3 cases of infections (5%), 9 cases of LSIL (15%), 23 cases of HSIL (38.3%), 2 cases (3.3%) each of ASCUS and SCC and 1 case (1.3%) AGUS were encountered.

Conclusions: Close follow-up and histologic examinations are necessary to avoid unnecessary spread of the neoplastic disease and untimely death of the patients. Awareness about diseases in FSWs and diagnostic utility of Pap test are also a must.

No MeSH data available.


Related in: MedlinePlus