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Cutaneous metastasis of transitional cell carcinoma of the urinary bladder: Cytological aspect.

Narayana MA, Patnayak R, Rukmangadha N, Chowhan AK, Kottu R, Phaneendra BV - J Cytol (2014)

Bottom Line: This case report describes a 51-year-old male who presented with multiple cutaneous metastases arising from high grade transitional cell carcinoma bladder with lamina propria invasion.The prominent cytological features include medium sized to large pleomorphic cells with irregular nuclear outlines, coarse chromatin pattern, and tumor giant cells.An awareness of this rare clinical entity and high index of suspicion is needed for diagnosis.

View Article: PubMed Central - PubMed

Affiliation: Department of Pathology, Sri Venkateswara Institute of Medical Sciences, Tirupati, Andhra Pradesh, India.

ABSTRACT
Cutaneous metastasis from transitional cell carcinoma urinary bladder is a rare clinical entity associated with poor prognosis. This case report describes a 51-year-old male who presented with multiple cutaneous metastases arising from high grade transitional cell carcinoma bladder with lamina propria invasion. The prominent cytological features include medium sized to large pleomorphic cells with irregular nuclear outlines, coarse chromatin pattern, and tumor giant cells. An awareness of this rare clinical entity and high index of suspicion is needed for diagnosis.

No MeSH data available.


Related in: MedlinePlus

High grade transitional cell carcinoma of bladder with tumor cells arranged in solid nests and islands (H and E, ×100)
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Figure 2: High grade transitional cell carcinoma of bladder with tumor cells arranged in solid nests and islands (H and E, ×100)

Mentions: In the past history, the patient had hematuria 10 months back for which he was evaluated in a different institute. There he underwent transurethral resection of bladder tumor. The histopathological examination revealed a high grade transitional cell carcinoma of bladder with lamina propria invasion [Figure 2]. After this, patient did not avail any therapy and he came to our institute with multiple skin nodules, 10 months later.


Cutaneous metastasis of transitional cell carcinoma of the urinary bladder: Cytological aspect.

Narayana MA, Patnayak R, Rukmangadha N, Chowhan AK, Kottu R, Phaneendra BV - J Cytol (2014)

High grade transitional cell carcinoma of bladder with tumor cells arranged in solid nests and islands (H and E, ×100)
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4150344&req=5

Figure 2: High grade transitional cell carcinoma of bladder with tumor cells arranged in solid nests and islands (H and E, ×100)
Mentions: In the past history, the patient had hematuria 10 months back for which he was evaluated in a different institute. There he underwent transurethral resection of bladder tumor. The histopathological examination revealed a high grade transitional cell carcinoma of bladder with lamina propria invasion [Figure 2]. After this, patient did not avail any therapy and he came to our institute with multiple skin nodules, 10 months later.

Bottom Line: This case report describes a 51-year-old male who presented with multiple cutaneous metastases arising from high grade transitional cell carcinoma bladder with lamina propria invasion.The prominent cytological features include medium sized to large pleomorphic cells with irregular nuclear outlines, coarse chromatin pattern, and tumor giant cells.An awareness of this rare clinical entity and high index of suspicion is needed for diagnosis.

View Article: PubMed Central - PubMed

Affiliation: Department of Pathology, Sri Venkateswara Institute of Medical Sciences, Tirupati, Andhra Pradesh, India.

ABSTRACT
Cutaneous metastasis from transitional cell carcinoma urinary bladder is a rare clinical entity associated with poor prognosis. This case report describes a 51-year-old male who presented with multiple cutaneous metastases arising from high grade transitional cell carcinoma bladder with lamina propria invasion. The prominent cytological features include medium sized to large pleomorphic cells with irregular nuclear outlines, coarse chromatin pattern, and tumor giant cells. An awareness of this rare clinical entity and high index of suspicion is needed for diagnosis.

No MeSH data available.


Related in: MedlinePlus