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Years of life lost as a measure of cancer burden on a national level.

Brustugun OT, Møller B, Helland A - Br. J. Cancer (2014)

Bottom Line: Lung cancer caused almost as many YLL alone (22.1% of cancer-caused YLL) as colon, prostate and breast cancer combined (23.1%).From 1997 to 2012, cancer-caused YLL as a fraction of all YLL increased from 32.5% to 35.2%, but with major differences among diagnoses.Public health efforts and research funding should be explicitly directed at preventing premature deaths.

View Article: PubMed Central - PubMed

Affiliation: 1] Department of Oncology, Oslo University Hospital-The Norwegian Radium Hospital, Oslo, Norway [2] Institute of Clinical Medicine, University of Oslo, Oslo, Norway.

ABSTRACT

Background: The severity of cancers is often measured in number of deaths. However, number of years of life lost (YLL) may be a more appropriate indicator of impact on society. Here we have calculated the YLL of adult cancers in Norway for the year 2012, as well as for the previous 15-year period.

Methods: Data on age composition, expected remaining years of life, total numbers of deaths and deaths due to cancer were retrieved from the National Census Agency Statistics Norway. YLL were calculated for both sexes aged 25-99 years based on each individual's age at death, and the expected remaining years of life at that age.

Results: Cancer deaths represented 25.8% of all adult deaths in 2012, with a lower fraction of females (28.7% in men and 23.1% in women), whereas cancer represented 35.2% of all YLL, with a higher fraction of females (32.8% in men and 37.8% in women). Females loose on average more life years to cancer than men (14.9 vs 12.7 years). Average YLL varied from 23.7 (cervical cancer) to 7.9 (prostate cancer). Lung cancer caused almost as many YLL alone (22.1% of cancer-caused YLL) as colon, prostate and breast cancer combined (23.1%). From 1997 to 2012, cancer-caused YLL as a fraction of all YLL increased from 32.5% to 35.2%, but with major differences among diagnoses.

Conclusions: Cancer is a major and increasing cause of premature deaths, and YLL may be a more accurate measure than number of deaths. Public health efforts and research funding should be explicitly directed at preventing premature deaths.

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Related in: MedlinePlus

YLL caused by lung, colon and prostate cancer for men (A), and by lung, breast and colon cancer for women (B), shown for 5-year age groups from 25 to 99 years in Norway in 2012.
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fig4: YLL caused by lung, colon and prostate cancer for men (A), and by lung, breast and colon cancer for women (B), shown for 5-year age groups from 25 to 99 years in Norway in 2012.

Mentions: For the four major cancer diagnoses, distinct differences in age distribution of YLL are seen when plotting YLL against age (Figure 4). Colon cancer claims YLL predominantly in high ages, especially among women, and this is even more evident for prostate cancer which reaches peak YLL in the 80–84-year age group. In women up to the age of 55, breast cancer is representative of the largest loss of life years, but thereafter, lung cancer is the major cancer cause of YLL loss also in women. For lung cancer, the highest YLL is found around 70 years for both sexes, whereafter a steep decrease is seen, in line with a decline in mortality rates in the highest age groups for lung cancer (data not shown).


Years of life lost as a measure of cancer burden on a national level.

Brustugun OT, Møller B, Helland A - Br. J. Cancer (2014)

YLL caused by lung, colon and prostate cancer for men (A), and by lung, breast and colon cancer for women (B), shown for 5-year age groups from 25 to 99 years in Norway in 2012.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4150272&req=5

fig4: YLL caused by lung, colon and prostate cancer for men (A), and by lung, breast and colon cancer for women (B), shown for 5-year age groups from 25 to 99 years in Norway in 2012.
Mentions: For the four major cancer diagnoses, distinct differences in age distribution of YLL are seen when plotting YLL against age (Figure 4). Colon cancer claims YLL predominantly in high ages, especially among women, and this is even more evident for prostate cancer which reaches peak YLL in the 80–84-year age group. In women up to the age of 55, breast cancer is representative of the largest loss of life years, but thereafter, lung cancer is the major cancer cause of YLL loss also in women. For lung cancer, the highest YLL is found around 70 years for both sexes, whereafter a steep decrease is seen, in line with a decline in mortality rates in the highest age groups for lung cancer (data not shown).

Bottom Line: Lung cancer caused almost as many YLL alone (22.1% of cancer-caused YLL) as colon, prostate and breast cancer combined (23.1%).From 1997 to 2012, cancer-caused YLL as a fraction of all YLL increased from 32.5% to 35.2%, but with major differences among diagnoses.Public health efforts and research funding should be explicitly directed at preventing premature deaths.

View Article: PubMed Central - PubMed

Affiliation: 1] Department of Oncology, Oslo University Hospital-The Norwegian Radium Hospital, Oslo, Norway [2] Institute of Clinical Medicine, University of Oslo, Oslo, Norway.

ABSTRACT

Background: The severity of cancers is often measured in number of deaths. However, number of years of life lost (YLL) may be a more appropriate indicator of impact on society. Here we have calculated the YLL of adult cancers in Norway for the year 2012, as well as for the previous 15-year period.

Methods: Data on age composition, expected remaining years of life, total numbers of deaths and deaths due to cancer were retrieved from the National Census Agency Statistics Norway. YLL were calculated for both sexes aged 25-99 years based on each individual's age at death, and the expected remaining years of life at that age.

Results: Cancer deaths represented 25.8% of all adult deaths in 2012, with a lower fraction of females (28.7% in men and 23.1% in women), whereas cancer represented 35.2% of all YLL, with a higher fraction of females (32.8% in men and 37.8% in women). Females loose on average more life years to cancer than men (14.9 vs 12.7 years). Average YLL varied from 23.7 (cervical cancer) to 7.9 (prostate cancer). Lung cancer caused almost as many YLL alone (22.1% of cancer-caused YLL) as colon, prostate and breast cancer combined (23.1%). From 1997 to 2012, cancer-caused YLL as a fraction of all YLL increased from 32.5% to 35.2%, but with major differences among diagnoses.

Conclusions: Cancer is a major and increasing cause of premature deaths, and YLL may be a more accurate measure than number of deaths. Public health efforts and research funding should be explicitly directed at preventing premature deaths.

Show MeSH
Related in: MedlinePlus